Mandibular reconstruction in adults: a review

International Journal of Oral and Maxillofacial Surgery

Volumn 37, Issue 7, 2008, Pages 597-605

  Goh, Bee Tin ^a   Lee, Shermin ^a   Tideman, Henk ^a   Stoelinga, Paul J W ^b  

^a National Dental Centre of Singapore   (Singapore)

^b RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

mandible; reconstruction

Indexed keywords

BONE DEVELOPMENT; BONE GRAFT; CANCER RADIOTHERAPY; COMPUTER ASSISTED TOMOGRAPHY; ENDOPROSTHESIS; FREE TISSUE GRAFT; HUMAN; JAW MALFORMATION; MANDIBLE; MANDIBLE RECONSTRUCTION; MOUTH CANCER; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; QUALITY OF LIFE; REVIEW; SURGEON; TISSUE ENGINEERING; TREATMENT OUTCOME;

ADULT; BONE PLATES; BONE TRANSPLANTATION; HUMANS; MANDIBLE; MANDIBULAR DISEASES; RECONSTRUCTIVE SURGICAL PROCEDURES; SURGICAL FLAPS;

EID: 46149103862     PISSN: 09015027     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijom.2008.03.002     Document Type: Review

References (128)

1. Ahlman E, Patzakis M, Roidis N, Sheperd L, Holtom P. Comparison of anterior and posterior iliac crest bone grafts in terms of harvest-site morbidity and functional outcomes. J Bone Joint Surg Am 2002:84:716-20.
2. Axhausen W. The osteogenic phases of regeneration of bone: A historical and experimental study. J Bone Joint Surg 38-A (1956) 593-600
3. Bell M.S., and Barron P.T. A new method of oral reconstruction using a free composite foot flap. Ann Plast Surg 5 (1980) 281-287
4. Boyne P.J. Restoration of osseous defects in maxillofacial casualties. J Am Dent Assoc 78 (1969) 767-776
5. Brown J.S., Magennis P., Rogers S.N., Cawood J.I., Howell R., and Vaughan E.D. Trends in head and neck microvascular reconstructive surgery in Liverpool (1992-2001). Br J Oral Maxillofac Surg. 44 (2006) 364-370
6. Bundgaard T., Tandrup O., and Elbrond O. A functional evaluation of patients treated for oral cancer. A prospective study. Int J Oral Maxillofac Surg. 22 (1993) 28-34
7. Chen Z., and Wu T. Reconstruction of mandibular defects with composite autologous iliac bone and freeze-treated allogeneic rib grafts. J Oral Maxillofac Surg. 40 (1982) 29-33
8. Cheung L.K., Samman N., Tong C.K., and Tideman H. Mandibular reconstruction with dacron urethane tray: A radiologic assessment of bone remodeling. J Oral Maxillofac Surg 52 (1994) 373-380
9. Cheung L.K., Samman N., Chow T.W., Clark R.K.F., and Tideman H. A bone graft condensing syringe system for maxillofacial reconstructive surgery. Br J Oral Maxillofac Surg 35 (1997) 267-270
10. Codivilla A. On the means of lengthening, in lower limbs, the muscles and tissues which are shortened through deformity. Am J Orthop Surg 2 (1904) 353-369
11. Colangelo L.A., Logemann J.A., Pauloski B.R., Pelzer J.R., and Rademaker A.W. T stage and functional outcome in oral and oropharyngeal cancer patients. Head Neck 18 (1996) 259-268
12. Conley J. Use of composite flaps containing bone for major repair in head and neck. Plast Reconstr Surg 49 (1972) 522-526
13. Costantino P.D., Johnson C.S., Friedman C.D., and Sissons Sr. G.A. Bone regeneration within a segmental human mandible defect: a preliminary report. Am J Otolaryngol 16 (1995) 56-65
14. Costantino P.D., Shybut G., Friedman C.D., Pelzer H.L., Masini M., Shindo M.L., and Sisson Sr. G.A. Segmental mandibular regeneration by distraction osteogenesis: an experimental study. Arch Otolaryngol Head Neck Surg 116 (1990) 535-545
15. Cuono B.C., and Ariyan S. Immediate reconstruction of a composite mandibular defect with a regional osteomyocutaneous flap. Plast Reconstr Surg 65 (1980) 477-483
16. Curtis D.A., Plesh O., and Miller A.J. A comparison of masticatory function in patients with or without reconstruction of the mandible. Head Neck Surg 19 (1997) 287-296
17. Daniel R.K. Free rib transfer by microvascular anastomoses. Plast Reconstr Surg 59 (1977) 737-738
18. DeFries Ho, Marble H.B., and Sell K.W. Reconstruction of the mandible: Use of a homograft combined with autogenous bone and marrow. Arch Otolaryngol. 93 (1971) 426-432
19. Dimitroulis G. Mandibular reconstruction following ablative tumour surgery: an overview of treatment planning. Aust N Z J Surg 70 (2000) 120
20. Esser E., and Wagner W. Dental implants following radical oral cancer surgery and adjuvant radiotherapy. Int J Oral Maxillofac Implants 12 (1997) 552-557
21. Ewers R., and Wangerin K. The autoclaved autogenous reimplant, an immediately replaced, mineral frame. J Maxillofac Surg 14 (1986) 138-142
22. Fennis J.P.M., Stoelinga P.J.W., and Jansen J.A. Mandibular reconstruction: a clinical and radiographic animal study on the use of autogenous scaffolds and platelet-rich plasma. Int J Oral Maxillofac Surg 31 (2001) 281-286
23. Fennis J.P.M., Stoelinga P.J.W., and Jansen J.A. Mandibular reconstruction: a histological and histomorphometric study on the use of autogenous scaffolds, particulate cortico-cancellous bone grafts and platelet rich plasma in goats. Int J Oral Maxillofac Surg 33 (2004) 48-55
24. Fiala T.G., Paige K.T., Davis T.L., Campbell T.A., Rosen B.R., and Yaremchuk M.J. Comparison of artifact from craniomaxillofacial internal fixation devices: magnetic resonance imaging. Plast Reconstr Surg 93 (1994) 725
25. Foster R.D., Anthony J.P., Sharma A., and Pogrel M.A. Vascularized bone flaps versus nonvascularized bone grafts for mandibular reconstruction: an outcome analysis of primary bony union and endosseous implant success. Head Neck 21 (1999) 66-71
26. Gellrich N.-C., Suarez-Cunqueiro M.M., Otero-Cepeda X.L., Schön R., Schmelzeisen R., and Gutwald R. Comparative study of locking plates in mandibular reconstruction after ablative tumour surgery: THORP versus UniLOCK system. J Oral Maxillofac Surg 62 (2004) 186-193
27. Gilbert A., and Teot L. The free scapular flap. Plast Reconstr Surg. 69 (1982) 601-604
28. Granick M.S., Newton E.D., and Hanna D.C. Scapular free flap for repair of massive lower facial composite defects. Head Neck Surg. 8 (1986) 436-441
29. Green M.F., Gibson J.R., Bryson J.R., and Thomson E. A one-stage correction of mandibular defects using a split sternum pectoralis major myocutaneous transfer. Br J Plast Surg 34 (1981) 11-16
30. Hamaker R. Irradiated autogenous mandibular grafts in primary reconstructions. Laryngoscope 91 (1981) 1031-1051
31. Hamaker R., and Singer M. Irradiated mandibular autografts update. Arch Otolaryngol Head Neck Surg 112 (1986) 277-279
32. Harding R. Follow-up clinic. Replantation of the mandible in cancer surgery. Plast Reconstr Surg. 48 (1971) 586-587
33. Harding R. Replantation of the mandible in cancer surgery. Plast Reconstr Surg 19 (1957) 373-383
34. Hartman H.M., Spauwen P.H.M., and Jansen J.A. Donor-site complications in vascularized bone flap surgery. J Invest Surg. 15 (2002) 185-197
35. Herford A.S. Use of a plate-guided distraction device for transport distraction osteogenesis of the mandible. J Oral Maxillofac Surg 62 (2004) 412-420
36. Herter N.T., Godoy P.R., and Kroef R.G. Mandibular reconstruction with osteomyocutaneous flaps. In: Soutar D.S., and Tiwari R. (Eds). Excision and Reconstruction in Head and Neck Cancer (1994), Churchill Livingstone, Edinburgh 37-78
37. Hidalgo D. Fibular free flap: A new method of mandible reconstruction. Plast Reconstr Surg. 84 (1989) 71
38. Hidalgo D.A., and Pusic A.L. Free-flap mandibular reconstruction: A 10-year follow-up study. Plast Reconstr Surg. 110 (2002) 438-449
39. Horiuchi K., Hattori A., Inada I., Kamibayashi T., Sugimura M., Yajima H., and Tamai S. Mandibular reconstruction using the double barrel fibular graft. Microsurgery 16 (1995) 450-454
40. Hueston J.T., and McConchie I.H. A compound pectoral flap. Austr N Z J Surg 67 (1968) 143-150
41. Hutchison I. Reconstructive surgery - bone and cartilage harvesting. In: Langdon J.D., and Patel M.F. (Eds). Operative Maxillofacial Surgery (1998), Chapman and Hall Medical, London 93-110
42. Ilizarov G. The tension-stress effect on the genesis and growth of tissues: part I. The influence of stability of fixation and soft-tissue preservation. Clin Orthop Relat Res 238 (1989) 249-281
43. Ilizarov G. The tension-stress effect on the genesis and growth of tissues: part II. The influence of the rate and frequency of distraction. Clin Orthop Relat Res 239 (1989) 263-285
44. Jisander S., Aspenberg P., Salemark L., and Wennerberg J. Mandibular reconstruction by secondary reimplantation of resected segments: a preliminary report. Int J Oral Maxillofac Surg 24 (1995) 288-292
45. Kessler P., Thorwarth M., Bloch-Birkholz A., Nkenke E., and Neukam F.W. Harvesting of bone from the iliac crest - comparison of the anterior and posterior sites. Br J Oral Maxillofac Surg 43 (2005) 51-56
46. Kim M.R., and Donoff R.B. Critical analysis of mandibular reconstruction using AO reconstruction plates. J Oral Maxillofac Surg 50 (1992) 1152-1157
47. Kim Y., Smith J., Sercarz J.A., Head C., Abemayor E., and Blackwell K.E. Fixation of mandibular osteotomies: comparison of locking and nonlocking hardware. Head Neck. 29 (2007) 453-457
48. Kinoshita Y., Kobayashi M., Hidaka T., and Ikada Y. Reconstruction of mandibular continuity defects in dogs using poly (L-lactide) mesh and autogenic particulate cancellous bone and marrow: Preliminary report. J Oral Maxillofac Surg 55 (1997) 718-723
49. Klapp R., and Schröder H. Die Unterkieferschussbrüche und ihre Behandlung (1917), Verlag von Hermann Meusser, Berlin
50. Kline S.N., and Rimer S.R. Reconstruction of osseous defects with freeze-dried allogeneic and autogenous bone: Clinical and histologic assessment. Am J Surg. 146 (1983) 471-473
51. Kruger E., and Krumholz K. Results of bone grafting after rigid fixation. J Oral Maxillofac Surg 42 (1984) 491-496
52. Kuriakose M.A., Shnayder Y., and Delacure M.D. Reconstruction of segmental mandibular defects by distraction osteogenesis for mandibular reconstruction. Head Neck 25 (2003) 816-824
53. Leake D.L., and Rappoport M. Mandibular reconstruction: Bone induction in an alloplastic tray. Surgery 72 (1972) 332-336
54. Louis P., Holmes J., and Fernandes R. Resorbable mesh as a containment system in reconstruction of the atrophic mandible fracture. J Oral Maxillofac Surg 62 (2004) 719-723
55. Lowlicht R.A., Delacure M.D., and Sasaki C.T. Allogeneic (homograft) reconstruction of the mandible. Laryngoscope 100 (1990) 837-843
56. Luhr H.-G. Entwicklung der modernen Osteosynthese. Mund Kiefer GesichtsChir 4 (2000) S84
57. Mainous EG, Boyne PJ, Hart GB, Terry BC. Restoration of resected mandible by grafting with combination of mandible homograft and autogenous iliac marrow and postoperative treatment with hyperbaric oxygenation. Oral Surg 1973; 35:13-20.
58. Martola M., Lindqvist C., Hanninen H., and Al-Sukhun J. Fracture of titanium plates used for mandibular reconstruction following ablative tumor surgery. J Biomed Mater Res B Appl Biomater 80 (2007) 345-352
59. Marx R.E., Carlson E.R., Eichstaedr R.M., Schimmele S.R., Strauss J.E., and Geogeff K.R. Platelet-rich-plasma: growth factor enhancement for bone grafts. Oral Surg 85 (1998) 638-646
60. Marx R.E., Kline S.N., Johnson R.P., Malinin T.I., Matthews II J.G., and Gambill V. The use of freeze-dried allogeneic bone in oral and maxillofacial surgery. J Oral Surg. 39 (1981) 264-274
61. McCarthy J.G., Schreiber J., Karp N., Thorne C.H., and Grayson B.H. Lengthening the human mandible by gradual distraction. Plast Reconstr Surg 89 (1992) 1-8
62. McKee DM. Microvascular bone transplantation. Clin Plast Surg 1978: 5: 283-292.
63. Merkx M.A.W., Fennis J.P.M., Verhagen C.M., and Stoelinga P.J.W. Reconstruction of the mandible using pre-shaped 2.4 mm titanium plates, autogenous particulate cortico-cancellous bone grafts and platelet rich plasma: a report on eight patients. Int J Oral Maxillofac Surg 33 (2004) 733-739
64. Mowlem R. Report of eighty-five cancellous chip grafts. Lancet 2 (1944) 746-748
65. Nerem R.M., and Sambanis A. Tissue engineering: from biology to biological substitutes. Tissue Eng 1 (1995) 3-13
66. Nocini P.F., Wangerin K., Albanese M., Kretschmer W., and Cortelazzi R. Vertical distraction of a free vascularized fibula flap in a reconstructed hemimandible: a case report. J Craniomaxillofac Surg. 28 (2000) 20-24
67. Nunez V.A., Pike J., Avery C., Rosson J.W., and Johnson P. Prophylactic plating of the donor site of osteocutaneous radial forearm flaps. Br J Oral Maxillofac Surg. 37 (1999) 210-212
68. O'Brien B.M., Morrison W.A., MacLeod A.M., and Dooley B.J. Microvascular osteocutaneous transfer using the groin flap and iliac crest and dorsalis pedis flap and second metatarsal. Br J Plast Surg 32 (1979) 188-206
69. Orell S. Surgical bone grafting with "os purum" and "os novum" and "boiled bone". J Bone Joint Surg 19 (1937) 873-885
70. Plotnikov N.A., and Sysoljatin P.G. Mandibular primary osteoplasty using orthotopic allografts. J Craniomaxillofac Surg 21 (1993) 43-49
71. Rappaport I. The particulate graft in tumour surgery. Am J Surg 122 (1971) 748-755
72. Riediger D. Restoration of masticatory function by microsurgically revascularized iliac crest bone grafts using enosseous implants. Plast Reconstr Surg. 81 (1988) 861-877
73. Robertson G.A. The role of sternum in osteomyocutaneous reconstruction of major mandibular defects. Am J Surg 152 (1986) 367-370
74. Rogers S.N., Lakshmiah S.R., Narayan B., Lowe D., Brownson P., Brown J.S., and Vaughan E.D. A comparison of the long term morbidity following deep circumflex iliac and fibula free flaps for reconstruction following head and neck cancer. Plast Reconstr Surg. 112 (2003) 1517-1525
75. Rogers S.N., Lowe D., Fisher S.E., Brown J.S., and Vaughan E.D. Health-related quality of life and clinical function after primary surgery for oral cancer. Br J Oral Maxillofac Surg. 40 (2002) 11-18
76. Rogers S.N., McNally D., Mahmood M., Chan M., and Humphris G.M. The psychological response of the edentulous patient following primary surgery for oral cancer: a cross-sectional study. J Prosthet Dent. 82 (1999) 317-321
77. Rohner D., Jaquiery C., Kunz C., Bucher P., Maas H., and Hammer B. Maxillofacial reconstruction with prefabricated osseous free flaps: a 3-year experience with 24 patients. Plast Reconstr Surg 112 (2003) 748-757
78. Sacco A.G., and Chepeha D.B. Current status of transport-disc-distraction osteogenesis for mandibular reconstruction. Lancet Oncol 8 (2007) 323-330
79. Salibian A.H., Rappaport I., Furnas D.W., and Achauer B.M. Microvascular reconstruction of the mandible. Am J Surg 140 (1980) 499-502
80. Samman N., Luk W.K., Chow T.W., Cheung L.K., Tideman H., and Clark R.K.F. Custom-made titanium mandibular reconstruction tray. Aust Dental J. 44 (1999) 195-199
81. Schepers R.H., Slagter A.P., Kaanders J.H.A.M., van der Hoogen F.J.A., and Merkx M.A.W. Effect of postoperative radiotherapy on the functional result of implants placed during ablative surgery for oral cancer. Int J Oral Maxillofac Surg. 35 (2006) 803-808
82. Schliephake H., and Hausamen J.E. An overview of the principles of reconstructive surgery. In: Ward Booth P., Schendel S.A., and Hausamen J.E. (Eds). Maxillofacial Surgery. 2nd Edn (2007), Churchill Livingstone, St Louis 535-548
83. Schliephake H., and Jamil M. Impact of intraoral soft-tissue reconstruction on the development of quality of life after ablative surgery in patients with oral cancer. Plast Reconstr Surg 109 (2002) 421-430
84. Schliephake H., Neukam F.W., Schmelzeisen R., Varoga B., and Schneller H. Long-term Quality of life after ablative intraoral tumour surgery. J Craniomaxillofac Surg. 23 (1995) 243-249
85. Schliephake H., Neukam F.W., Schmelzeisen R., and Wichmann M. Long-term results of endosteal implants used for restoration of oral function after oncologic surgery. Int J Oral Maxillofac Surg 28 (1999) 260-265
86. Schliephake H., Ruffert K., and Schneller T. Prospective study of the quality of life of cancer patients after intraoral tumor surgery. J Oral Maxillofac Surg. 54 (1996) 664-669
87. Schoen P.J., Raghoebar G.M., Bouma J., Reintsema H., Burlage F.R., Rooddenburg J.L.N., and Vissink A. Prosthodontic rehabilitation of oral function in head-neck cancer patients with dental implants placed simultaneously during ablative tumour surgery: an assessment of treatment outcomes and quality of life. Int J Oral Maxillofac Surg 37 (2008) 8-16
88. Schoen P.J., Reintsema H., Raghoebar G.M., Vissink A., and Roodenburg J.L.N. The use of implant retained mandibular prostheses in the oral rehabilitation of head and neck cancer patients. A review and rationale for treatment planning. Oral Oncol. 40 (2004) 862-871
89. Schwartz H.C., Leake D.L., and Pizzofenato A. Evaluation of autologous cancellous bone grafting of mandibular discontinuity defects in dogs using dacron-urethane prosthesis. J Oral Maxillofac Surg 45 (1987) 143-148
90. Schwartz H.C., Wollin M., Leake D.L., and Kagan A.R. Interface radiation dosimetry in mandibular reconstruction. Arch Otolaryngol 105 (1979) 293-295
91. Sclaroff A., Haughey B., Gay W.D., and Paniello R. Immediate mandibular reconstruction and placement of dental implants at the time of ablative surgery. Oral Surg Oral Med Oral Pathol 78 (1994) 711-717
92. Serafin D., Villarreal-Rios A., and Georgiade N.G. A rib-containing free flap to reconstruct mandibular defects. Br J Plast Surg 30 (1977) 263-266
93. Shaw R.J., Sutton A.F., Cawood J.I., Howell R.A., Lowe D., Brown J.S., Rogers S.N., and Vaughan E.D. Oral rehabilitation after treatment for head and neck malignancy. Head Neck 27 (2005) 459-470
94. Shibahara T., Noma H., Furuya Y., and Takaki R. Fracture of mandibular reconstruction plates used after tumor resection. J Oral Maxillofac Surg 60 (2002) 182-185
95. Simon E.N.M., Merkx M.A.W., Shubi F.M., Kalyanyama B.M., and Stoelinga P.J.W. Reconstrcution of the mandible after ablative surgery for the treatment of aggressive, benign odontogenic tumours in Tanzania: a preliminary study. Int J Oral Maxillofac Surg. 35 (2006) 421-426
96. Snyder C.C., Levine G.A., Swanson H.M., and Browne Jr. E.Z. Mandibular lengthening by gradual distraction: preliminary report. Plast Reconstr Surg 51 (1973) 506-508
97. Song R., Gao Y., Song Y., Yu Y., and Song Y. The forearm flap. Clin Plast Surg. 9 (1982) 21-26
98. Soutar D.S., Scheker L.R., Tanner N.S., and McGregor I.A. The radial forearm flap: a versatile method for intra-oral reconstruction. Br J Plast Surg. 36 (1983) 1-8
99. Swartz W.M., Banis J.C., Newton E.D., Ramasastry S.S., Jones N.F., and Acland R. The osteocutaneous scapular flap for mandibular and maxillary reconstruction. Plast Reconstr Surg. 77 (1986) 530-545
100. Sykoff W, Zur Frage der Knochenplastik am Unterkiefer. Zentralbl Chir1900:35
101. Tayapongsak P., O'Brien D.A., Monteiro C.B., and Arceo-Diaz L.Y. Autologous fibrin adhesive in mandibular reconstruction with particulate cancellous bone and marrow. J Oral Maxillofac Surg 52 (1994) 161-165
102. Taylor G.I., Miller G.D.H., and Ham F.J. The free vascularized bone graft. Plast Reconstr Surg. 55 (1975) 533-544
103. Taylor G.I., Townsend P., and Corlett R. Superiority of the deep circumflex iliac vessels as the supply for free groin flaps. Clinical work. Plast Reconstr Surg. 64 (1979) 745-759
104. Teot L., Bosse J.P., and Mourfarrege R. The scapular crest pedicled bone graft. Int J Microsurg. 3 (1981) 257-262
105. Terheyden H., Knak C., Jepsen S., Palmie S., and Rueger D.R. Mandibular reconstruction with a prefabricated vascularized bone graft using recombinant human osteogenic protein-1: an experimental study in miniature pigs. Part I: Prefabrication. Int J Oral Maxillofac Surg. 30 (2001) 373-379
106. Terheyden H., Menzel C., Wang H., Springer I.N., Rueger D.R., and Acil Y. Prefabrication of vascularized bone grafts using recombinant human osteogenic protein-1--part 3: dosage of rhOP-1, the use of external and internal scaffolds. Int J Oral Maxillofac Surg. 33 (2004) 164-172
107. Thorn J.J., Sorensen H., Weis Fogh U., and Andersen M. Autologous fibrin glue with growth factors in reconstructive maxillofacial surgery. Int J Oral Maxillofac Surg 33 (2004) 95-100
108. Tideman H. Complete rehabilitation of the lower jaw after segmental resection: a new method. J Craniomaxillofac Surg 24 suppl 1 (1996) 176
109. Tideman H., and Lee S. The TL endoprosthesis for mandibular reconstruction - a metallic yet biological approach. Asian J Oral Maxillofac Surg 18 (2006) 5
110. Tideman H., Samman N., and Cheung L.K. Functional reconstruction of the mandible: a modified titanium mesh system. Int J Oral Maxillofac Surg. 27 (1998) 339-345
111. Tiwari R. Mandibular reconstruction with conventional bone graft. In: Soutar D.S., and Tiwari R. (Eds). Excision and Reconstruction in Head and Neck Cancer (1994), Churchill Livingstone, Edinburgh 59-85
112. Tonino A., Davidson C.L., Klopper P.J., and Linelau L.A. Protection from stress in bone and its effects. J Bone Joint Surg Am 58 (1976) 107-113
113. Urken M.L., Buchbinder D., Weinberg H., Vickery C., Sheiner A., and Biller H.F. Primary placement of osseointegrated implants in microvascular mandible reconstruction. Otolaryngol Head Neck Surg. 101 (1989) 56-73
114. Urken M.L., Buchbinder D., Weinberg H., Vickery C., Sheiner A., Parker R., Schaefer J., Som P., Shapiro A., Lawson W., et al. Functional evaluation following microvascular oromandibular reconstruction of the oral cancer patient: A comparative study of reconstructed and nonreconstructed patients. Laryngoscope 101 (1991) 935-950
115. Urken M.L., Vickery C., Weinberg H., Buchbinder D., Lawson W., and Biller H.F. The internal oblique-iliac crest osseomyocutaneous free flap in oromandibular reconstruction. Report of 20 cases. Arch Otolaryngol Head Neck Surg. 115 (1989) 339-349
116. Van Cann E.M., Dom M., Koole R., Merkx M.A.W., and Stoelinga P.J.W. Health related quality of life after mandibular resection for oral and oropharyngeal sqamous cell carcinoma. Oral Oncol 41 (2005) 687-693
117. Vaughan E.D., Bainton R., and Martin I.C. Improvements in morbidity of mouth cancer using microvascular free flap reconstructions. J Craniomaxillofac Surg 20 (1992) 132-134
118. Wangerin K., Ewers R., Wottge H.U., and Randzio G. The autoclaved autogenous bone graft as a reimplant: Results of animal experiments. J Maxillofac Surg 14 (1986) 132-137
119. Warnke P.H., Springer I.N., Wiltfang J., Acil Y., Eufinger H., Wehmoller M., Russo P.A., Bolte H., Sherry E., Behrens E., and Terheyden H. Growth and transplantation of a custom vascularised bone graft in a man. Lancet 364 (2004) 766-770
120. Warnke P.H., Wiltfang J., Springer I., Acil Y., Bolte H., Kosmahl M., Russo P.A., Sherry E., Lutzen U., Wolfart S., and Terheyden H. Man as living bioreactor: fate of an exogenously prepared customized tissue-engineered mandible. Biomaterials 27 (2006) 3163-3167
121. Weinzweig N., Jones N.F., Shestak K.C., Moon H.K., and Davies B.W. Oromandibular reconstruction using a keel-shaped modification of the radial forearm osteocutaneous flap 33 (1994) 359-369
122. Weischer T., and Mohr C. Ten-year experience in oral implant rehabilitation of cancer patients: treatment concept and proposed criteria for success. Int J Oral Maxillofac Implants 12 (1999) 521-528
123. Werkmeister R., Szulczewski D., Walteros-Benz P., and Joos U. Rehabilitation with dental implants of oral cancer patients. J Craniomaxillofac Surg 27 (1999) 38-41
124. Whitman D.H., Berry R.I., and Green D.M. Platelet gel: an autologous alternative to fibrin glue with applications in oral and maxillofacial surgery. J Oral Maxillofac Surg 55 (1997) 1295-1299
125. Wilk R.M. Bony reconstruction of the jaws. In: Miloro M. (Ed). Peterson's Principles of Oral and Maxillofacial Surgery. 2nd edn (2004), BC Decker, Hamilton-London 783-801
126. Wilson K.M., Rizk N.M., Armstrong S.L., and Gluckman J.L. Effects of hemimandibulectomy on quality of life. Laryngoscope 108 (1998) 1574-1577
127. Wodajo F.M., Bickels J., Wittig J., and Malawer M. Complex reconstruction in the management of extremity sarcomas. Curr Opin Oncol 15 (2003) 304-312
128. Yang G., Chen B., and Gao Y. Forearm free skin flap transplantation. Natl Med J China. 61 (1981) 139