Man as living bioreactor: Fate of an exogenously prepared customized tissue-engineered mandible

Biomaterials

Volumn 27, Issue 17, 2006, Pages 3163-3167

  Warnke, Patrick H ^a   Wiltfang, Jörg ^a   Springer, Ingo ^a   Acil, Yahya ^a   Bolte, Hendrik ^a   Kosmahl, Markus ^a   Russo, Paul A J ^a,b   Sherry, Eugene ^c   Lützen, Ulf ^a   Wolfart, Stefan ^a   Terheyden, Hendrik ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b UNIVERSITY OF SYDNEY   (Australia)

^c BOND UNIVERSITY   (Australia)

Author keywords

Bioreactor; BMP; Bone regeneration; In vivo tissue engineering; Mandible reconstruction; Replacement

Indexed keywords

GENETIC ENGINEERING; MUSCLE; PATIENT TREATMENT; TISSUE CULTURE;

BMP; BONE REGENERATION; IN VIVO TISSUE ENGINEERING; MANDIBLE RECONSTRUCTION; REPLACEMENT;

BIOREACTORS;

BONE MORPHOGENETIC PROTEIN; OSTEOGENIC PROTEIN 1; RECOMBINANT PROTEIN; TITANIUM;

BIOREACTOR; BONE BIOPSY; BONE REGENERATION; BONE SCINTISCANNING; COMPUTER ASSISTED TOMOGRAPHY; EXPERIENCE; EXPERIMENTAL MODEL; HUMAN; IN VIVO CULTURE; LATISSIMUS DORSI MUSCLE; MANDIBLE; MANDIBLE RECONSTRUCTION; MOUTH CANCER; PRIORITY JOURNAL; REVIEW; TECHNIQUE; TISSUE ENGINEERING; TRANSPLANTATION;

ANIMALIA;

EID: 33644749291     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2006.01.050     Document Type: Article

References (8)

1. P.H. Warnke, I.N. Springer, J. Wiltfang, Y. Acil, H. Eufinger, and M. Wehmoller Growth and transplantation of a custom vascularised bone graft in a man Lancet 28 364 2004 766 770
2. B.D. MacArthur, and R.O.C. Oreffo Bridging the gap Nature 433 2005 19
3. M. Spector Basic principles of tissue engineering. Chapter 1. Tissue engineering 1999 Quintessence Publishing Co. Inc. Chicago, USA
4. H. Terheyden, C. Knak, S. Jepsen, S. Palmie, and D.R. Rueger Mandibular reconstruction with a prefabricated vascularized bone graft using recombinant human osteogenic protein-1: an experimental study in miniature pigs. Part I: Prefabrication Int J Oral Maxillofac Surg 30 2001 373 379
5. H. Terheyden, P. Warnke, A. Dunsche, S. Jepsen, W. Brenner, and S. Palmie Mandibular reconstruction with prefabricated vascularized bone grafts using recombinant human osteogenic protein-1: an experimental study in miniature pigs. Part 2: transplantation Int J Oral Maxillofacial Surg 30 2001 469 478
6. P.H. Warnke, I.N. Springer, Y. Acil, G. Julga, J. Wiltfang, and K. Ludwig The mechanical integrity of in vivo engineered heterotopic bone Biomaterials 27 7 2006 1081 1087 (Epub 2005 August 24)
7. A. Takushima, K. Harii, H. Asato, T. Nakatsuka, and Y. Kimata Mandibular reconstruction using microvascular free flaps: a statistical analysis of 178 cases Plast Reconstr Surg 108 2001 1555 1563
8. S. Gronthos Reconstruction of human mandible by tissue engineering Lancet 364 9436 2004 735 736