Inhibitory effects of cholesterol derivatives on DNA polymerase and topoisomerase activities, and human cancer cell growth

Lipids

Volumn 43, Issue 4, 2008, Pages 373-382

  Ishimaru, Chisato ^a   Yonezawa, Yuko ^a   Kuriyama, Isoko ^a   Nishida, Masayuki ^a   Yoshida, Hiromi ^a   Mizushina, Yoshiyuki ^a  

^a KOBE GAKUIN UNIVERSITY   (Japan)

Author keywords

Cell cycle arrest; Cell growth inhibition; Cholesterol derivatives; Cholesteryl hemisuccinate; Cholesteryl 5 , 6 epoxide; DNA polymerase; DNA topoisomerase; Enzyme inhibitor; Sodium cholesteryl sulfate

Indexed keywords

APHIDICOLIN; CAMPTOTHECIN; CHOLESTEROL; CHOLESTEROL BROMIDE; CHOLESTEROL CHLORIDE; CHOLESTEROL DERIVATIVE; CHOLESTEROL HYDROGEN SUCCINATE; CHOLESTEROL SULFATE; CHOLESTERYL 5ALPHA,6ALPHA EPOXIDE; DNA POLYMERASE; DNA TOPOISOMERASE; ETOPOSIDE; SODIUM CHOLESTERYL SULFATE;

ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; LD 50;

ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL PROLIFERATION; CHOLESTEROL; DNA TOPOISOMERASES; DNA-DIRECTED DNA POLYMERASE; ENZYME INHIBITORS; HL-60 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; NEOPLASMS;

ANIMALIA;

EID: 46149087086     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/s11745-007-3149-y     Document Type: Article

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