Early findings of small-animal MRI and small-animal computed tomography correlate with histological changes in a rat model of rheumatoid arthritis

NMR in Biomedicine

Volumn 21, Issue 5, 2008, Pages 527-536

  Lee, Sheen Woo ^a,d   Greve, Joan M ^b   Leaffer, David ^c   Lollini, Lance ^c   Bailey, Patricia ^c   Gold, Garry E ^a   Biswal, Sandip ^a,c,d  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Stanford University   (United States)

^c Roche Palo Alto ^*  (United States)

^d STANFORD UNIVERSITY   (United States)

Author keywords

Computed tomography; Histology; MRI; Rheumatoid arthritis small animal imaging

Indexed keywords

COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC RADIOGRAPHY; IMAGING TECHNIQUES; INJECTION (OIL WELLS); MEDICAL IMAGING; RATS; THERMOGRAPHY (TEMPERATURE MEASUREMENT); TOMOGRAPHY;

ANIMAL MODELS; COMPLETE FREUND'S ADJUVANT; COMPUTED TOMOGRAPHY; HISTOLOGICAL CHANGES; HISTOLOGY; MICRO-CT; MRI; RAT MODELS; RHEUMATOID ARTHRITIS; RHEUMATOID ARTHRITIS SMALL-ANIMAL IMAGING; SMALL ANIMALS; SMALL-ANIMAL IMAGING; X-RAY COMPUTED TOMOGRAPHY;

HEALTH;

FREUND ADJUVANT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE EROSION; BONE MARROW; CONTROLLED STUDY; COVARIANCE; FEMALE; HISTOPATHOLOGY; JOINT EFFUSION; LINEAR REGRESSION ANALYSIS; MICRO-COMPUTED TOMOGRAPHY; MOLECULAR IMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; RHEUMATOID ARTHRITIS; SCORING SYSTEM; SWELLING; SYNOVITIS;

ANIMALS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; BIOMEDICAL RESEARCH; BONE DENSITY; BONE RESORPTION; DISEASE MODELS, ANIMAL; EDEMA; FEMALE; FOOT; FREUND'S ADJUVANT; HYDRARTHROSIS; MAGNETIC RESONANCE IMAGING; RATS; RATS, INBRED LEW; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, X-RAY COMPUTED;

ANIMALIA; RATTUS;

EID: 46049084788     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.1225     Document Type: Article

References (18)

1. Silva MD, Savinainen A, Kapadia R, Ruan J, Siebert E, Avitahl N, Mosher R, Anderson K, Jaffee B, Schopf L, Chandra S. Quantitative analysis of micro-CT imaging and histopathological signatures of experimental arthritis in rats. Mol Imaging 2004; 3(4): 312-318.
2. Barck KH, Lee WP, Diehl LJ, Ross J, Gribling P, Zhang Y, Nguyen K, van Bruggen N, Hurst S, Carano RA. Quantification of cortical bone loss and repair for therapeutic evaluation in collagen-induced arthritis, by micro-computed tomography and automated image analysis. Arthritis Rheum 2004; 50(10): 3377-3386.
3. Faure P, Doan BT, Beloeil JC. In-vivo high resolution three-dimensional MRI studies of rat joints at 7 T. NMR Biomed 2003; 16(8): 484--493.
4. Goldbach-Mansky R, Woodbum J, Yao L, Lipsky PE. Magnetic resonance imaging in the evaluation of bone damage in rheumatoid arthritis: a more precise image or just a more expensive one? Arthritis Rheum 2003; 48(3): 585-589.
5. Lutz AM, Gopfert K, Jochum W, Nanz D, Frohlich JM, Weishaupt D. USPIO-enhanced MR imaging for visualization of synovial hyperperfusion and detection of synovial macrophages: preliminary results in an experimental model of antigen-induced arthritis. J Magn Reson Imaging 2006; 24(3): 657-666.
6. Ostergaard M. Magnetic resonance imaging in rheumatoid arthritis. Quantitative methods for assessment of the inflammatory process in peripheral joints. Dan Med Bull 1999; 46(4): 313-344.
7. Loeuille D, Gonord P, Guingamp C, Gillet P, Blum A, Sauzade M, Netter P. In vitro magnetic resonance microimaging of experimental osteoarthritis in the rat knee joint. J Rheumatol 1997; 24(1): 133-139.
8. Yu Y, Xiong Z, Lv Y, Qian Y, Jiang S, Tian Y. In vivo evaluation of early disease progression by X-ray phase-contrast imaging in the adjuvant-induced arthritic rat. Skeletal Radiol 2006; 35(3): 156-164.
9. Zwerina J, Hayer S, Tohidast-Akrad M, Bergmeister H, Redlich K, Feige U, Dunstan C, Kollias G, Steiner G, Smolen J, Schett G. Single and combined inhibition of tumor necrosis factor, interleukin-1, and RANKL pathways in tumor necrosis factor-induced arthritis: effects on synovial inflammation, bone erosion, and cartilage destruction. Arthritis Rheum 2004; 50(1): 277-290.
10. Shu G, Yamamoto K, Nagashima M. Differences in osteoclast formation between proximal and distal tibial osteoporosis in rats with adjuvant arthritis: inhibitory effects of bisphosphonates on osteoclasts. Mod Rheumatol 2006; 16(6): 343-349.
11. Schett G, Redlich K, Smolen JS. The role of osteoprotegerin in arthritis. Arthritis Res Ther 2003; 5(5): 239-245.
12. Roberts MJ, Adams SB Jr, Patel NA, Stamper DL, Westmore MS, Martin SD, Fujimoto JG, Brezinski ME. A new approach for assessing early osteoarthritis in the rat. Anal Bioanal Chem 2003; 377(6): 1003-1006.
13. Bove SE, Calcaterra SL, Brooker RM, Huber CM, Guzman RE, Juneau PL, Schrier DJ, Kilgore KS. Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis. Osteoarthritis Cartilage 2003; 11(11): 821-830.
14. Jaffre B, Watrin A, Loeuille D, Gillet P, Netter P, Laugier P, Saied A. Effects of antiinflammatory drugs on arthritic cartilage: a high-frequency quantitative ultrasound study in rats. Arthritis Rheum 2003; 48(6): 1594-1601.
15. Huysmans MC, Longbottom C. The challenges of validating diagnostic methods and selecting appropriate gold standards. J Dent Res 2004; 83 Spec No C: C48-52.
16. Pearson CM. Experimental models in rheumatoid disease. Arthritis Rheum 1964; 26: 80-86.
17. van den Berg WB. Animal models of arthritis. What have we learned? J Rheumatol Suppl 2005; 72: 7-9.
18. Pearson CM, Wood FD. Studies of arthritis and other lesions induced in rats by the injection of mycobacterial adjuvant. VII. Pathologic details of the arthritis and spondylitis. Am J Pathol 193; 42: 73-95.