LC-MS determination and relative bioavailability of doxazosin mesylate tablets in healthy Chinese male volunteers

Journal of Pharmaceutical and Biomedical Analysis

Volumn 43, Issue 3, 2007, Pages 1049-1056

  Ma, Ning ^a,b   Liu, Wenying ^a   Li, Huande ^b   Chen, Benmei ^c   Zhu, Yungui ^b   Liu, Xiaolei ^b   Wang, Feng ^b   Xiang, Daxiong ^b   Zhang, Bikui ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Bioavailability; Doxazosin mesylate; Quadrupole mass spectrometer

Indexed keywords

ACETONITRILE; AMMONIUM ACETATE; DIMETHYL ETHER; DOXAZO; DOXAZOSIN; DOXAZOSIN MESYLATE; METHANOL; N HEXYLANE TERT BUTYLMETHYL ETHER; TERAZOSIN; UNCLASSIFIED DRUG;

ACCURACY; ADULT; AQUEOUS SOLUTION; AREA UNDER THE CURVE; ARTICLE; DRUG BIOAVAILABILITY; DRUG DETERMINATION; DRUG ISOLATION; DRUG MONITORING; HALF LIFE TIME; HUMAN; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PH; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SEPARATION TECHNIQUE; SINGLE DRUG DOSE; STANDARD; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADRENERGIC ALPHA-ANTAGONISTS; ADULT; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CALIBRATION; CHROMATOGRAPHY, LIQUID; CROSS-OVER STUDIES; DOXAZOSIN; FREEZING; HALF-LIFE; HUMANS; MALE; MASS SPECTROMETRY; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SOLUTIONS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TABLETS; THERAPEUTIC EQUIVALENCY;

EID: 33846640542     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2006.09.013     Document Type: Article

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