Cyclosporin production in various solid substrate media by Tolypocladium inflatum (ATCC 34921)

Biotechnology

Volumn 7, Issue 2, 2008, Pages 357-359

  Nisha, A K ^a,b   Ramasamy, K ^a  

^a SRM INSTITUTE OF SCIENCE AND TECHNOLOGY   (India)

^b Al Margeb University   (Libyan Arab Jamahiriya)

Author keywords

Biomass; Cyclosporin; Solid substrate fermentation (SSF); Solid substrates; Submerged fermentation

Indexed keywords

BIOCHEMICAL ENGINEERING; BIOMASS; FERMENTATION; METABOLITES; RENEWABLE ENERGY RESOURCES; SUBSTRATES;

CYCLOSPORIN; RICE BRANS; RICE HUSK; SECONDARY METABOLITES; SOLID SUBSTRATE; SOLID SUBSTRATE FERMENTATION (SSF); SOLID SUBSTRATES; SOLID-STATE FERMENTATION; SUBMERGED FERMENTATION; WHEAT BRAN;

GRAIN (AGRICULTURAL PRODUCT);

ARACHIS HYPOGAEA; HELIANTHUS; MICROPUS; TOLYPOCLADIUM INFLATUM; TRITICUM AESTIVUM;

EID: 45949104145     PISSN: 1682296X     EISSN: 16822978     Source Type: Journal    
DOI: 10.3923/biotech.2008.357.359     Document Type: Article

References (17)

1. Balaraman K. and N. Mathews, 1997. Process for the preparation of cyclosporin A from Tolypocladium species. U.S. PatentNo. 5: 656, 459.
2. Balaraman, K. and N. Mathews, 2006. Optimization of media composition for the production of cyclosporin A by Tolypocladium species. Ind. J. Med. Res., 123: 525-530.
3. De Souza, D.F. and P.M. Peralta, 2001. Production of amylase by Aspergillus tamari in solid state fermentation at high initial glucose concentrations. Acta Scientiarum, 23 (2): 599-602.
4. Holker, U., M. Hofer and J. Lenz, 2004. Biotechnological advantages of laboratory-scale solid state fermentation with fungi. Applied Microbiol. Biotechnol., 64: 175-186.
5. Holker, U. and J. Lenz, 2005. Solid-state fermentations are there any biotechnical advantages. Curr. Opin. Microbiol., 8 (3): 301-306.
6. Hoppert, M., C. Gentzch and K. Schorgendrofer, 2001. Structure and localization of cyclosporin synthetase. The key enzyme of cyclosporin biosynthesis in Tolypocladium inflation. Arch. Microbiol., 176(1): 285-293.
7. Kang, S.W., S.H. Lee, C.S. Yoon and S.W. Kim, 2005. Conidia production by Beauveria bassiana (for the biocontrol of a diamondback moth) during solid-state fermentation in a packed-bed bioreactor. Biotechnol. Lett., 27: 135-139.
8. Lee, J. and S.N. Agathos, 1989. Effect of amino acids on the production of cyclosporin A by Tolypocladium inflation. Biotechnol. Lett., 11: 77-82.
9. Leung, P.H., Q.X. Zhang and J.Y. Wu, 2006. Mycelium cultivation, chemical composition and antitumour activity of a Tolupocladium sp. Fungus isolated from wild Cordeyceps sinensis. J. Applied Microbiol., 101 (2): 275-283.
10. Nisha, A.K. and N. Kannan, 2005. A comparative study on the production of cyclosporin in submerged and solid-state fermentation process. Ind. J. Applied Microbiol., pp: 95-97.
11. Nisha, A.K., N. Kannan and A. Michael, 2005. Production of cyclosporin in Solid-State fermentation by Tolypocladium inflatum. Ind. I. Applied Microbiol., pp: 57-60.
12. Pandey, A., 1991. Aspects of fermenter design for Solidstate fermentations. Process Biochem., 26: 355-361.
13. Ramana Murthy, M.V., E.V.S. Mohan and A.K. Sadhukhan, 1999. Cyclosporin A production by Tolypocladium inflatum using solid state fermentation. Process Biochem., 34: 269-280.
14. Robinson, T., D. Singh and P. Nigam, 2001. Solid state fermentation: A promising technology for secondary metabolite production. Applied Microbiol. Biotechnol, 55 (3): 284-289.
15. Sekar, C. and K. Balaraman, 1998. Optimization studies on the production of cyclosporin A by solid state fermentation. Bioprocess. Eng., 18: 293-296.
16. Tengerdy, R.P., 1985. Solid-state fermentations. Trends. Biotechnol, 3: 96-99.
17. Wei, M., M. Sasmita, G. Katrina, P.M. Jyoti, N. Devki, E.R. Neil, BA. Jonathan and K. Ashok, 2007. Cyclosporin A and FK506 inhibit IL-12p40 production through the calmdulin/calmodulin-dependent protein kinase-activated phosphoino-sitide 3-kinase in lipopolysaccharide-stimulated human monocytic cells. J. Biol. Chem., 282 (18): 13351-13362.