Leptin affects proliferation-, apoptosis- and protein kinase A-related peptides in human ovarian granulosa cells

Physiological Research

Volumn 57, Issue 3, 2008, Pages 437-442

  Sirotkin, Alexander V ^a   Mlyncek M ^b   Makarevich, A V ^a   Florkovicova I ^a   Hetenyi L ^a  

^a RESEARCH INSTITUTE OF ANIMAL PRODUCTION   (Slovakia)

^b Faculty Hospital Nitra   (Slovakia)

Author keywords

Bax; Cyclin B; Leptin; Ovary; PCNA; Protein kinase A

Indexed keywords

BAX PROTEIN, HUMAN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN B; CYCLIN B1; CYCLINE; LEPTIN; PROTEIN BAX; RECOMBINANT PROTEIN;

ADULT; APOPTOSIS; ARTICLE; CELL CULTURE; CELL CYCLE; CELL PROLIFERATION; ENZYMOLOGY; FEMALE; GRANULOSA CELL; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADULT; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CELL CYCLE; CELL PROLIFERATION; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIN B; FEMALE; GRANULOSA CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; LEPTIN; PROLIFERATING CELL NUCLEAR ANTIGEN; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

EID: 45849151759     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. AGARWAL SK, VOGEL K, WEITSMAN SR, MAGOFFIN DA: Leptin antagonizes the insulin-like growth factor-I augmentation of steroidogenesis in granulosa and theca cells of the human ovary. J Clin Endocr Metab 84: 1072-1076, 1999.
2. ALMOG B, GOLD R, TAJMA K, DANTES A, SELIM K, RUBINSTEIN M, BARKAN D, HOMBURG R, LESSING JB, NEVO N, GERTLER A, AMSTERDAM A: Leptin attenuates follicular apoptosis and accelerates the onset of puberty in immature rats. Mol Cell Endocrinol 183: 179-191, 2001.
3. CHAFFIN CL, SCHWINOF KM, STOUFFER RL: Gonadotropin and steroid control of granulosa cell proliferation during the periovulatory interval in rhesus monkeys. Biol Reprod 65: 755-762, 2001.
4. 2 secretion in cultured rat ovarian follicles. Reproduction 123: 891-898, 2002.
5. HAMM ML, BHAT GK, THOMPSON WE, MANN DR: Folliculogenesis is impaired and granulosa cell apoptosis is increased in leptin-deficient mice. Biol Reprod 71: 66-72, 2004.
6. HUANG H, CHEN D, ZHU Y, YANG X, JIN M, JI M: Study of effects of leptin on cultured human luteinized granulosa cell function (in Chinese) Zhonghua Fu Chan Ke Za Zhi. 37: 152-154, 2002.
7. KADAKIA R., ARRAZTOA JA, BONDY C, ZHOU J: Granulosa cell proliferation is impaired in the IGF-1 null ovary. Growth Horm. IGF Res 11: 220-224, 2001.
8. KIKUCHI N, ANDOH K, ABE Y, YAMADA K, MIZUMA H, IBUKI Y: Inhibitory action of leptin on early follicular growth differs in immature and adult female mice. Biol Reprod 65: 66-71, 2001.
9. KITAWAKI J, KUSUKI I, KOSHIBA H, TSUKAMOTO K, HONJO H: Leptin directly stimulates aromatase activity in human luteinized granulosa cells. Mol Hum Reprod 5: 708-713, 1999.
10. MATSUOKA T, TAHARA M, YOKOI T, MASUMOTO N, TAKEDA T, YAMAGUCHI M, TASAKA K, KURACHI H, MURATA Y: Tyrosine phosphorylation of STAT3 by leptin through leptin receptor in mouse metaphase 2 stage oocyte. Biochem Biophys Res Commun 256: 480-484, 1999.
11. MURPHY BD: Models of luteinization. Biol Reprod 63: 2-11, 2002.
12. NARYZHNY SN, LEE H: Protein profiles of the Chinese hamster ovary cells in the resting and proliferating stages. Electrophoresis 22: 1764-1775, 2001.
13. OSBORN M, ISENBERG S: Immunocytochemistry of frozen and paraffin tissue sections. In: Cell Biology. A Laboratory Handbook Vol. 2, CELIS JE (ed), New York, Academic Press, 1994, pp. 361-367.
14. RICHARDS JC: New signalling pathways for hormones and cyclic 3′, 5′-monophosphate action on endocrine cells. Mol Endocrinol 15: 209-218, 2001.
15. RUIZ-CORTES ZT, MARTEL-KENNES Y, GEVRY NY, DOWNEY BR, PALIN MF, MURPHY BD: Biphasic effects of leptin in porcine granulosa cells. Biol Reprod 68: 789-796, 2003.
16. SMITH GD, JACKSON LM, FOSTER DL: Leptin regulation of reproductive function and fertility. Theriogenology 57: 73-86, 2001.
17. SPICER LJ: Leptin: a possible metabolic signal affecting reproduction. Dom Anim Endocrinol 21: 251-270, 2001.
18. SPICER LJ, CHAMBERLAIN CS, FRANCISCO CC: Ovarian action of leptin: effects on insulin-like growth factor-I-stimulated function of granulosa and thecal cells. Endocrine 12: 53-59, 2000.
19. SIROTKIN AV, MLYNCEK M, KOTWICA J, MAKAREVICH AV, FLORKOVICOVA I, HETENYI L: Leptin directly controls secretory activity of human ovarian granulose cells: possible inter-relationship with IGF/IGFBP system. Hormone Res 64: 198-202, 2005.