Vascular endothelial growth factor attenuates hepatic sinusoidal capillarization in thioacetamide-induced cirrhotic rats

World Journal of Gastroenterology

Volumn 14, Issue 15, 2008, Pages 2349-2357

  Xu, Hao ^a   Shi, Bao Min ^a   Lu, Xiao Fei ^a   Liang, Feng ^a   Jin, Xing ^a   Wu, Tai Huang ^a   Xu, Jian ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Fenestrae; Gene array; Hepatic sinusoid capillarization; Liver cirrhosis; Transmission electrical microscopy; Ultrastructure; Vascular endothelial growth factor

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; PLASMID DNA; THIOACETAMIDE; VASCULOTROPIN;

ANGIOGENESIS; ANGIOGENIC GENE THERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ULTRASTRUCTURE; CYTOPLASM; GENE EXPRESSION; GENETIC TRANSFECTION; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER CIRRHOSIS; LIVER SINUSOID; MALE; MICROARRAY ANALYSIS; NONHUMAN; PORTAL HYPERTENSION; PORTAL VEIN BLOOD PRESSURE; RAT; TRANSMISSION ELECTRON MICROSCOPY;

EID: 45849145397     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.14.2349     Document Type: Article

References (38)

1. Wisse E. An electron microscopic study of the fenestrated endothelial lining of rat liver sinusoids. J Ultrastruct Res 1970; 31: 125-150
2. Braet F. How molecular microscopy revealed new insights into the dynamics of hepatic endothelial fenestrae in the past decade. Liver Int 2004; 24: 532-539
3. Irie S, Tavassoli M. Transendothelial transport of macromolecules: the concept of tissue-blood barriers. Cell Biol Rev 1991; 25: 317-333, 340-341
4. Braet F, Spector I, Shochet N, Crews P, Higa T, Menu E, de Zanger R, Wisse E. The new anti-actin agent dihydrohali-chondramide reveals fenestrae-forming centers in hepatic endothelial cells. BMC Cell Biol 2002, 3:7
5. Fraser R, Dobbs BR, Rogers GW. Lipoproteins and the liver sieve: the role of the fenestrated sinusoidal endothelium in lipoprotein metabolism, atherosclerosis, and cirrhosis. Hepatology 1995; 21: 863-874
6. Braet F, Fraser R, McCuskey RS. Thirty-five years of liver sinusoidal cells: Eddie Wisse in retirement. Hepatology 2003; 38: 1056-1058
7. Braet F, Wisse E. Structural and functional aspects of liver sinusoidal endothelial cell fenestrae: a review. Comp Hepatol 2002; 1: 1
8. Xu GF, Wang XY, Ge GL, Li PT, Jja X, Tian DL, Jiang LD, Yang JX. Dynamic changes of capillarization and peri-sinusoid fibrosis in alcoholic liver diseases. World J Gastroenterol 2004; 10: 238-243
9. Franceschini B, Ceva-Grimaldi G, Russo C, Dioguardi N, Grizzi F. The complex functions of mast cells in chronic human liver diseases. Dig Dis Sci 2006; 51: 2248-2256
10. Yokomori H, Oda M, Yoshimura K, Nagai T, Ogi M, Nomura M, Ishii H. Vascular endothelial growth factor increases fenestral permeability in hepatic sinusoidal endothelial cells. Liver Int 2003; 23: 467-475
11. Esser S, Wolburg K, Wolburg H, Breier G, Kurzchalia T, Risau W. Vascular endothelial growth factor induces endothelial fenestrations in vitro. J Cell Biol 1998; 140: 947-959
12. Chen J, Braet F, Brodsky S, Weinstein T, Romanov V, Noiri E, Goligorsky MS. VEGF-induced mobilization of caveolae and increase in permeability of endothelial cells. Am J Physiol Cell Physiol 2002; 282: C1053-C1063
13. Nagy JA, Feng D, Vasile E, Wong Shih SC, Dvorak AM, Dvorak HF. Permeability properties of tumor surrogate blood vessels induced by VEGF-A. Lab Invest 2006; 86: 767-780
14. Ballermann BJ. Contribution of the endothelium to the glomerular permselectivity barrier in health and disease. Nephron Physiol 2007; 106: p19-p25
15. Shi BM, Wang XY, Mu QL, Wu TH, Liu HJ, Yang Z. Angiogenesis effect on rat liver after administration of expression vector encoding vascular endothelial growth factor D. World J Gastroenterol 2003; 9: 312-315
16. Makhlouf MM, Awad A, Zakhari MM, Fouad M, Saleh WA. Vascular endothelial growth factor level in chronic liver diseases. J Egypt Soc Parasitol 2002; 32: 907-921
17. Giatromanolaki A, Kotsiou S, Koukourakis MI, Sivridis E. Angiogenic factor expression in hepatic cirrhosis. Mediators Inflamm 2007; 2007: 67187
18. Akiyoshi F, Sata M, Suzuki H, Uchimura. Y, Mitsuyama K, Matsuo K, Tanikawa K. Serum vascular endothelial growth factor levels in various liver diseases. Dig Dis Sci 1998; 43: 41-45
19. Genesca J, Gonzalez A, Mujal A, Ceroto F, Segura R. Vascular endothelial growth factor levels in liver cirrhosis. Dig Dis Sci 1999; 44: 1261-1262
20. Oe H, Kaido T, Furuyama H, Mori A, Imamura M. Simultaneous transfer of vascular endothelial growth factor and hepatocyte growth factor gene~ effectively promotes liver regeneration after hepatectpmy in cirrhotic rats. Hepatogastroenterology 2004; 51: 1641-1647
21. Oe H, Kaido T, Mori A, Onodera H, Imamura M. Hepatocyte growth factor as well as vascular endothelial growth factor gene induction effectively promotes liver regeneration after hepatectomy in Solt-Farber rats. Hepatogastroenterology 2005; 52:1393-1397
22. Ueno T, Nakamura T, Torimura T, Sata M. Angiogenic cell therapy for hepatic fibrosis. Med Mol Morphol 2006; 39: 16-21
23. Bueno M, Salgado S, Beas-Zarate C, Armendariz-Borunda J. Urokinase-type plasminogen activator gene therapy in liver cirrhosis is mediated by collagens gene expression down-regulation and up-regulation of MMPs, HGF and VEGF. J Gene Med 2006; 8: 1291-1299
24. Seglen PO. Preparation of isolated rat liver cells. Methods Cell Biol 1976; 13: 29-83
25. Weng HL, Ciuclan L, Liu Y, Hamzavi J, Godoy P, Gaitantzi H, Kanzler S, Heuchel R, Ueberham U, Gebhardt R, Breitkopf K, Dooley S. Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes. Hepatology 2007; 46: 1257-1270
26. Shiota G, Okubo M, Noumi T, Noguchi N, Oyama K, Takano Y, Yashima K, Kishimoto Y, Kawasaki H. Cyclooxygenase-2 expression in hepatocellular carcinoma. Hepatogastroenterology 1999; 46: 407-412
27. Yamada Y, Nezu J, Shimane M, Hirata Y. Molecular cloning of a novel vascular endothelial growth factor, VEGF-D. Genomics 1997; 42:483-488
28. Yan J, Chen W, Ma Y, Sun X. Expression of vascular endothelial growth factor in liver tissues of hepatitis B. Zhonghua Ganzangbing Zazhi 2000; 8: 150-152
29. Vale PR, Isner JM, Rosenfield K. Therapeutic angiogenesis in critical limb and myocardial ischemia. J Interv Cardiol 2001; 14: 511-528
30. Byzova TV, Goldman CK, Jankau J, Chen J, Cabrera G, Achen MG, Stacker SA, Carnevale KA, Siemionow M, Deitcher SR, DiCorleto PE. Adenovirus encoding vascular endothelial growth factor-D induces tissue-specific vascular patterns in vivo. Blood 2002; 99:4434-4442
31. Lee LY , Patel SR, Hackett,NR, Mack CA, Polce DR, El-Sawy T, Hachamovitch R, Zanzonico P, Sanborn TA, Parikh M, Isom OW, Crystal RG, Rosengart TK. Focal angiogen therapy using intramyocardial delivery of an adenovirus vector coding for vascular endothelial growth factor 121. Ann Thorac Surg 2000; 69: 14-23; discussion 23-24
32. Leotta E, Patejunas G, Murphy G, Szokol J, McGregor L, Carbray J, Hamawy A, Winchester D, Hackett N, Crystal R, Rosengart T. Gene therapy with adenovirus-mediated myocardial transfer of vascular endothelial growth factor 121 improves cardiac performance in a pacing model of congestive heart failure. J Thorac Cardiovasc Surg 2002; 123: 1101-1113
33. Deodato B, Arsic N, Zentilin L, Galeano M, Santoro D, Torre V, Altavilla D, Valdembri D, Bussolino F, Squadrito F, Giacca M. Recombinant AAV vector encoding human VEGF165 enhances wound healing. Gene Ther 2002; 9, 777-785
34. Risau W. Development and differentiation of endothelium. Kidney Int Suppl 1998; 67: S3-S6
35. Ballermann BJ. Contribution of the endothelium to the glomerular permselectivity barrier in health and disease. Nephron Physiol 2007; 106: p19-p25
36. Roberts WG, Palade GE. Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor. J Cell Sci 1995; 108 (Pt 6): 2369-2379
37. Roberts WG, Palade GE. Neovasculature induced by vascular endothelial growth factor is fenestrated. Cancer Res 1997; 57: 765-772
38. Corpechot C, Barbu V, Wendum D, Kinnman N, Rey C, Poupon R, Housset C, Rosmorduc O. Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis. Hepatology 2002; 35: 1010-1021