Artificial circulation of the liver: Machine perfusion as a preservation method in liver transplantation

Anatomical Record

Volumn 291, Issue 6, 2008, Pages 735-740

  Vekemans, Katrien ^a   Liu, Qiang ^a   Pirenne, Jacques ^a   Monbaliu, Diethard ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Hypothermic; Liver; Machine perfusion; Normothermic; Transplantation

Indexed keywords

PRESERVATION SOLUTION;

ANIMAL; ANIMAL MODEL; DOG; HUMAN; INSTRUMENTATION; LIVER CIRCULATION; LIVER TRANSPLANTATION; METHODOLOGY; ORGAN PRESERVATION; PERFUSION; RABBIT; RAT; REVIEW; SWINE; TEMPERATURE;

ANIMALS; DOGS; HUMANS; LIVER CIRCULATION; LIVER TRANSPLANTATION; MODELS, ANIMAL; ORGAN PRESERVATION; ORGAN PRESERVATION SOLUTIONS; PERFUSION; RABBITS; RATS; SUS SCROFA; TEMPERATURE;

EID: 45849145079     PISSN: 19328486     EISSN: 19328494     Source Type: Journal    
DOI: 10.1002/ar.20662     Document Type: Review

References (49)

1. Belzer FO. 1973. Evaluation of kidney-preservation methods. Lancet 1:1063-1065.
2. Belzer FO, May R, Berry MN, Lee JC. 1970. Short term preservation of porcine livers. J Surg Res 10:55-61.
3. Belzer FO, Glass NR, Sollinger HW, Hoffmann RM, Southard JH. 1982. A new perfusate for kidney preservation. Transplantation 33:322-323.
4. Bessems M, Doorschodt BM, Dinant S, de Graaf W, van Gulik TM. 2006. Machine perfusion preservation of the pig liver using a new preservation solution, polysol. Transplant Proc 38:1238-1242.
5. Bessems M, Doorschodt BM, van Marle J, Vreeling H, Meijer AJ, van Gulik TM. 2005a. Improved machine perfusion preservation of the non-heart-beating donor rat liver using Polysol: a new machine perfusion preservation solution. Liver Transpl 11:1379-1388.
6. Bessems M, Doorschodt BM, van Vliet AK, van Gulik TM. 2005b. Improved rat liver preservation by hypothermic continuous machine perfusion using polysol, a new, enriched preservation solution. Liver Transpl 11:539-546.
7. Boudjema K, Lindell SL, Belzer FO, Southard JH. 1991. Effects of method of preservation on functions of livers from fed and fasted rabbits. Cryobiology 28:227-236.
8. Brettschneider L, Kolff J, Smith GV, Martin AJ, Taylor P, Starzl TE. 1968. An evaluation of perfusion constituents in liver preservation. Surg Forum 19:354-356.
9. Compagnon P, Clement B, Campion JP, Boudjema K. 2001. Effects of hypothermic machine perfusion on rat liver function depending on the route of perfusion. Transplantation 72:606-614.
10. de Vries B, Snoeijs MG, von Bonsdorff L, Ernest van Heurn LW, Parkkinen J, Buurman WA. 2006. Redox-active iron released during machine perfusion predicts viability of ischemically injured deceased donor kidneys. Am J Transplant 6:2686-2693.
11. Derveaux K, Monbaliu D, Crabbe T, Schein D, Brassil J, Kravitz D, Fevery J, Jacobbi L, Roskams T, Pirenne J. 2005. Does ex vivo vascular resistance re.ect viability of non-heart-beating donor livers? Transplant Proc 37:338-339.
12. Dutkowski P, Krug A, Krysiak M, Dunschede F, Seifert JK, Junginger T. 2003. Detection of mitochondrial electron chain carrier redox status by transhepatic light intensity during rat liver reperfusion. Cryobiology 47:125-142.
13. Dutkowski P, Furrer K, Tian Y, Graf R, Clavien PA. 2006. Novel short-term hypothermic oxygenated perfusion (HOPE) system prevents injury in rat liver graft from non-heart beating donor. Ann Surg 244:968-976.
14. Ehringer WD, Su S, Chiangb B, Stillwell W, Chien S. 2002. Destabilizing effects of fructose-1,6-bisphosphate on membrane bilayers. Lipids 37:885-892.
15. Friend PJ, Imber C, St Peter S, Lopez I, Butler AJ, Rees MA. 2001. Normothermic perfusion of the isolated liver. Transplant Proc 33:3436-3438.
16. Gellert K, David H, Otto G, Uerlings I, Wolff H. 1985. Alteration of the ultrastructure of the pig liver after a continuous perfusion of six hours in vitro. Exp Pathol 28:245-250.
17. Grosse-Siestrup C, Unger V, Pfeffer J, Dinh QT, Nagel S, Springer J, Witt C, Wussow A, Groneberg DA. 2004. Hepatotoxic effects of polidocanol in a model of autologously perfused porcine livers. Arch Toxicol 78:697-705.
18. Guarrera JV, Estevez J, Boykin J, Boyce R, Rashid J, Sun S, Arrington B. 2005. Hypothermic machine perfusion of liver grafts for transplantation: technical development in human discard and miniature swine models. Transplant Proc 37:323-325.
19. Habib MM, Hafez TS, Parkes HG, Seifalian AM, Fuller BJ, Davidson BR. 2004. A comparison of bile composition from heart-beating and non-heart-beating rabbit organ donors during normothermic extracorporeal liver perfusion: experimental evaluation using proton magnetic resonance spectroscopy. Transplant Proc 36: 2914-2916.
20. Imber CJ, St Peter SD, de Cenarruzabeitia IL, Lemonde H, Rees M, Butler A, Clayton PT, Friend PJ. 2002a. Optimisation of bile production during normothermic preservation of porcine livers. Am J Transplant 2:593-599.
21. Imber CJ, St Peter SD, Lopez dC, I, Pigott D, James T, Taylor R, McGuire J, Hughes D, Butler A, Rees M, Friend PJ. 2002b. Advantages of normothermic perfusion over cold storage in liver preservation. Transplantation 73:701-709.
22. Iwamoto H, Matsuno N, Narumi Y, Uchiyama M, Kozaki K, Degawa H, Hama K, Kikuchi K, Takeuchi H, Kozaki M, Nagao T. 2000. Beneficial effect of machine perfusion preservation on liver transplantation from non-heart-beating donors. Transplant Proc 32:1645-1646.
23. Jain S, Lee CY, Baicu S, Duncan H, Xu H, Jones J, Clemens MG, Brassil J, Taylor MJ, Brockbank KGM. 2005. Hepatic function in hypothermically stored porcine livers: comparison of hypothermic machine perfusion vs cold storage. Transplant Proc 37:340-341.
24. Kim JS, Boudjema K, D'Alessandro A, Southard JH. 1997. Machine perfusion of the liver: maintenance of mitochondrial function after 48-hour preservation. Transplant Proc 29:3452-3454.
25. Lauschke H, Kotting M, Akbar S, Minor T. 2003. Use of taurine as antioxidant in resuscitating livers from non-heart-beating donors by gaseous oxygen persuf.ation. J Invest Surg 16:7-11.
26. Lee CY, Jain S, Duncan HM, Zhang JX, Jones JW Jr, Southard JH, Clemens MG. 2003. Survival transplantation of preserved non-heart-beating donor rat livers: preservation by hypothermic machine perfusion. Transplantation 76:1432-1436.
27. Minor T, Manekeller S, Sioutis M, Dombrowski F. 2006. Endoplasmic and vascular surface activation during organ preservation: refining upon the benefits of machine perfusion. Am J Transplant 6:1355-1366.
28. Monbaliu D, de Vries B, Crabbe T, van Heurn E, Verwaest C, Roskams T, Fevery J, Pirenne J, Buurman WA. 2005. Liver fatty acid-binding protein: an early and sensitive plasma marker of hepatocellular damage and a reliable predictor of graft viability after liver transplantation from non-heart-beating donors. Transplant Proc 37:413-416.
29. Monbaliu D, Brassil J, Heedfeld V, Dubbuisson C, Pirenne J, Vekemans K. 2006. Comparison of cold storage versus hypothermic machine perfusion in a preclinical model of liver transplantation (abstract). Am J Transplant Suppl 72.
30. Morariu AM, Vd Plaats A, V Oeveren W, 't Hart NA, Leuvenink HG, Graaff R, Ploeg RJ, Rakhorst G. 2003. Hyperaggregating effect of hydroxyethyl starch components and University of Wisconsin solution on human red blood cells: a risk of impaired graft perfusion in organ procurement? Transplantation 76:37-43.
31. Natori S, Selzner M, Valentino KL, Fritz LC, Srinivasan A, Clavien PA, Gores GJ. 1999. Apoptosis of sinusoidal endothelial cells occurs during liver preservation injury by a caspase-dependent mechanism. Transplantation 68:89-96.
32. Nishida S, Nakamura N, Kadono J, Komokata T, Sakata R, Madariaga JR, Tzakis AG. 2006. Intrahepatic biliary strictures after liver transplantation. J Hepatobiliary Pancreat Surg 13:511-516.
33. Nui A, Katsuramaki T, Kikuchi H, Kukita K, Kimura H, Meguro M, Nagayama M, Isobe M, Hirata K. 2006. The functional integrity of a normothermic perfusion system using artificial blood in pig liver. J Surg Res 131:189-198.
34. Olschewski P, Tolba R, Akbar S, Minor T. 2003. Use of HTK solution for hypothermic machine perfusion: an alternative for the preservation of less than optimal donor livers? - An experimental study in rats. Transplant Proc 35:767.
35. Pienaar BH, Lindell SL, Van Gulik T, Southard JH, Belzer FO. 1990. Seventy-two-hour preservation of the canine liver by machine perfusion. Transplantation 49:258-260.
36. Ploeg RJ, van Bockel JH, Langendijk PT, Groenewegen M, van der Woude FJ, Persijn GG, Thorogood J, Hermans J. 1992. Effect of preservation solution on results of cadaveric kidney transplantation. The European Multicentre Study Group. Lancet 340:129-137.
37. Reddy S, Greenwood J, Maniakin N, Bhattacharjya S, Zilvetti M, Brockmann J, James T, Pigott D, Friend P. 2005. Non-heart-beating donor porcine livers: the adverse effect of cooling. Liver Transpl 11:35-38.
38. Rossaro L, Murase N, Caldwell C, Farghali H, Casavilla A, Starzl TE, Ho C, Van Thiel DH. 1992. Phosphorus 31-nuclear magnetic resonance spectroscopy of rat liver during simple storage or continuous hypothermic perfusion. J Lab Clin Med 120:559-568.
39. Schon MR, Kollmar O, Wolf S, Schrem H, Matthes M, Akkoc N, Schnoy NC, Neuhaus P. 2001. Liver transplantation after organ preservation with normothermic extracorporeal perfusion. Ann Surg 233:114-123.
40. Slapak M, Wigmore RA, Wexler M, Giles G, Latzina A, McDermott WV. 1969. Normobaric and hyperbaric preservation of the liver, kidney, and heart in a manually portable apparatus. Trans Am Soc Artif Intern Organs 15:225-228.
41. Southard JH, Lindell S, Ametani M, Richer J-P, Vos AWF. 2000. Kupffer cell activation in liver preservation: cold storage vs machine perfusion. Transplant Proc 32:27-28.
42. 't Hart NA, der van Plaats A, Leuvenink HG, van Goor H, Wiersema-Buist J, Verkerke GJ, Rakhorst G, Ploeg RJ. 2007. Determination of an adequate perfusion pressure for continuous dual vessel hypothermic machine perfusion of the rat liver. Transpl Int 20:343-352.
43. Uchiyama M, Matsuno N, Hama K, Iwamoto H, Narumi Y, Kikuchi K, Degawa H, Kozaki K, Kubota K, Takeuchi H, Sakurai E, Asuwa N, Masuda Toshihiko HS, Nagao T. 2001. Comparison between nonpulsatile and pulsatile machine perfusion preservation in liver transplantation from non-heart-beating donors. Transplant Proc 33:936-938.
44. van Gulik TM, Reinders ME, Nio R, Frederiks WM, Bosma A, Klopper PJ. 1994. Preservation of canine liver grafts using HTK solution. Transplantation 57:167-171.
45. Vekemans K, Liu Q, Brassil J, Komuta M, Pirenne J, Monbaliu D. 2007. Influence of flow and addition of oxygen during porcine liver hypothermic machine perfusion. Transplant Proc 39:2647-2651.
46. Wight JP, Chilcott JB, Holmes MW, Brewer N. 2003. Pulsatile machine perfusion vs. cold storage of kidneys for transplantation: a rapid and systematic review. Clin Transplant 17:293-307.
47. Xu H, Lee CY, Clemens MG, Zhang JX. 2004. Pronlonged hypothermic machine perfusion preserves hepatocellular function but potentiates endothelial cell dysfunction in rat livers. Transplantation 77:1676-1682.
48. Xu H, Zhang JX, Jones JW, Southard JH, Clemens MG, Lee CY. 2005. Hypothermic machine perfusion of rat livers preserves endothelial cell function. Transplant Proc 37:335-337.
49. Yamamoto N, Konishi Y, Wakashiro S, Takayasu T, Tatsumi Y, Shimahara Y, Tanaka K, Yamaoka Y, Ozawa K. 1991. Seventy-two-hour preservation of porcine liver by continuous hypothermic perfusion with UW solution in comparison with simple cold storage. J Surg Res 51:288-292.