The functional integrity of a normothermic perfusion system using artificial blood in pig liver

Journal of Surgical Research

Volumn 131, Issue 2, 2006, Pages 189-198

  Nui, Akihiro ^a,b   Katsuramaki, Tadashi ^a   Kikuchi, Hitoshi ^a   Kukita, Kazuma ^a   Kimura, Hitoshi ^a   Meguro, Makoto ^a   Nagayama, Minoru ^a   Isobe, Masato ^a   Hirata, Koichi ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Hokkaido Children's Hospital and Medical Center   (Japan)

Author keywords

Amino acids; Artificial blood; Extracorporeal; Function; Liver; Normothermic; Perfusion

Indexed keywords

ALANINE; AMINO ACID; AMMONIA; ARGININE; AROMATIC AMINO ACID; ARTIFICIAL BLOOD; BICARBONATE; BOVINE SERUM ALBUMIN; BRANCHED CHAIN AMINO ACID; CITRULLINE; DEXAMETHASONE; GLUCOSE; GLUTAMINE; GLYCOGEN; HISTIDINE; HUMAN INSULIN; METHIONINE; ORNITHINE; POTASSIUM CHLORIDE; SERINE; SODIUM HYDROXIDE; TAURINE; THREONINE; UREA;

AMINO ACID ANALYSIS; AMINO ACID METABOLISM; AMINO ACID SYNTHESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; FEMALE; FUNCTIONAL ASSESSMENT; GLUCONEOGENESIS; GLYCOGEN SYNTHESIS; LIVER GRAFT; LIVER PERFUSION; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; SWINE; TISSUE LEVEL;

AMMONIA; ANIMALS; BLOOD SUBSTITUTES; FEMALE; LIVER; ORGAN CULTURE TECHNIQUES; OXYGEN CONSUMPTION; REGIONAL BLOOD FLOW; SWINE; TEMPERATURE; UREA;

EID: 33644910411     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2005.11.579     Document Type: Article

References (33)

1. D.P. Foley, F.J. Vittimberga, S.H. Quarfordt Biliary secretion of extracorporeal porcine liver with single and dual vessel perfusion Transplantation 68 1999 362
2. S. Rodriguez-Reynoso, E. Portilla, D. Garcia Blood flow rate and energy charge in the isolated perfused canine liver J Surg Res 99 2001 40 doi:10.1006/jsre.2001.6102.
3. N. Nakamura, Y. Kamiyama, S. Takai Ex vivo liver perfusion with arterial blood from a pig with ischemic liver failure Int J Artif Organs 23 1999 153
4. S.P. Horslen, J.M. Hammel, L.W. Fristoe Extracoporeal liver perfusion using human and pig livers for acute liver failure Transplantation 70 2000 1472
5. D.C. Borie, D. Eyraud, E. Boleslawski Functional metabolic characteristics of intact pig livers during prolonged extracorporeal perfusion potential for a unique biological liver-assist device Transplantation 72 2001 393
6. P. Dutkowski, B. Odermatt, T. Heinrich Hypothermic oscillating liver perfusion stimulate ATP synthesis prior to transplantation J Surg Res 80 1998 365 doi:10.1006/jsre.1998.5491.
7. M.R. Schön, O. Kollmar, S. Wolf Liver transplantation after organ preservation with normothermic extracorporeal perfusion Ann Surg 233 2001 114
8. A. Nui, T. Katsuramaki, H. Kikuchi Successful ex vivo normothermic liver perfusion with purely artificial products using artificial blood Int J Artif Organs 26 2003 46
9. R.F.P. Bertolo, P.B. Pencharz, R.O. Ball Organ and plasma amino acid concentrations are profoundly different in piglets fed identical diets via gastric, central venous or portal venous routes J Nutr 130 2000 1261
10. H.R. Horton, L.A. Moran, R.S. Ochs Amino acid metabolism J. Challice M. Ginsburg N.M. Bush Principles of Biochemistry 3rd ed. 2002 Prentice-Hall, Inc Upper Saddle River, NJ 530 565
11. D.L. Nelson, M.M. Cox Amino acid oxidation and the production of urea M. Ryan L. Strange V. Neal Lehninger Principles of Biochemistry 3rd ed. 2000 Worth Publishers New York 623 656
12. A.L. Bradley, M. Sika, J.K. Wright Hepatic uptake of amino acids immediately after liver transplantation is well preserved despite altered plasma profiles J Surg Res 74 1998 47 doi:10.1006/jsre.1997.5225.
13. P. Muriel Regulation of nitric oxide synthesis in the liver J Appl Toxicol 20 2000 189
14. I. Ioannidis, A. Hellinger, C. Dehmlow Evidence for increased nitric oxide production after liver transplantation in humans Transplantation 59 1995 1293
15. M. Hisanaga, Y. Nakajima, M. Segawa Evaluation of initial hepatic allograft function with changes of free plasma amino acids in canine orthotopic liver transplantation J Surg Res 50 1991 139
16. F. Langle, E. Roth, R. Steininger Arginase release following liver reperfusion. Evidence of hemodynamic action of arginase infusions Transplantation 59 1995 1542
17. E. Roth, R. Steininger, S. Winkler L-arginine deficiency after liver transplantation as an effect of arginase efflux from the graft. Influence on nitric oxide metabolism Transplantation 57 1994 665
18. S.K. Kim, J.M. Seo, Y.S. Jung Alterations in hepatic metabolism of sulfur-containing amino acids induced by ethanol in rats Amino Acids 24 2003 103
19. A.J. Cooper Biochemistry of sulfur-containing amino acids Ann Rev Biochem 52 1983 187
20. J.D. Finkelstein, J.J. Martin Homocysteine Int J Biochem Cell Biol 32 2000 385
21. M.H. Stipanuk Metabolism of sulfur-containing amino acids Ann Rev Nutr 6 1986 179
22. R.J. Huxtable Physiological actions of taurine Physiol Rev 72 1992 101
23. J.A. Timbrell, V. Seabra, C.J. Waterfield The in vivo and in vitro protective properties of taurine Gen Pharmacol 26 1995 453
24. O.I. Aruoma, B. Halliwell, B.M. Honey The antioxidant action of taurine, hypotaurine and their metabolic precursors Biochem J 256 1988 251
25. T.R. Mehta, R. Dawson Jr Taurine is a weak scavenger of peroxynitrite and does not attenuate sodium nitroprusside toxicity to cells in culture Amino Acids 20 2001 419
26. H.R. Horton, L.A. Moran, R.S. Ochs Additional pathways in carbohydrate metabolism J. Challice M. Ginsburg N.M. Bush Principles of Biochemistry 3rd ed. 2002 Prentice-Hall, Inc Upper Saddle River, NJ 399 428
27. D.L. Nelson, M.M. Cox Carbohydrate biosynthesis M. Ryan L. Strange V. Neal Lehninger Principles of Biochemistry 3rd ed. 2000 Worth Publishers New York 722 766
28. K. Arai, K. Lee, F. Berthiaume Intrahepatic amino acid and glucose metabolism in a D-galactosamine-induced rat liver failure model Hepatology 34 2001 360
29. C. Zimmermann, P. Ferenci, C. Pifl Hepatic encephalopathy in thioacetamide-induced acute liver failure in rats; characterization of an improved model and study of amino acid-ergic neurotransmission Hepatology 9 1989 594
30. C.O. Record, B. Buxton, R.A. Chase Plasma and brain amino acids in fulminant hepatic failure and their relationship to hepatic encephalopathy Eur J Clin Invest 6 1976 387
31. H.M. Rosen, N. Yoshimura, J.M. Hodgman Plasma amino acid patterns in hepatic encephalopathy of differing etiology Gastroenterology 72 1977 483
32. J.E. Fischer, J.M. Funovics, A. Aguirre The role of plasma amino acids in hepatic encephalopathy Surgery 78 1975 276
33. M.R. Schön, W. Heil, H.P. Lemmens Xenogenic, extracorporeal liver perfusion in primates improves the ratio of branched-chain amino acids to aromatic amino acids (Fischer's ratio) Eur Surg Res 31 1999 230