The effect of antioxidant treatment and NOS inhibition on the incidence of ischaemia-induced arrhythmias in the diabetic rat heart

Physiological Research

Volumn 57, Issue SUPPL. 2, 2008, Pages

  Matejikova J ^a   Kucharska J ^b   Pancza, D ^a   Ravingerova T ^a,c  

^a Institute for Heart Research   (Slovakia)

^b Faculty of Medicine of Comenius University and University Hospital Bratislava   (Slovakia)

^c INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

Adaptation; Antioxidant treatment; Arrhythmias; Myocardial ischaemia

Indexed keywords

EID: 45849140831     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. ANDELOVÁ E, BARTEKOVÁ M, PANCZA D, STYK J, RAVINGEROVÁ T: The role of NO in ischemia/reperfusion injury in isolated rat heart. Gen Physiol Biophys 24: 411-426, 2005.
2. ANDELOVÁ E, PINTÉROVÁ M, ŠIMONČ ÍKOVÁ P, BARANČÍK M, ONDREJČÁ KOVÁ M, PECHÁŇOVÁ O, STYK J, RAVINGEROVÁ T.: Dual role of NO in susceptibility to ischemia/reperfusion injury in the rat heart. Physiol Res 55: 1P, 2006.
3. BOLLI R: Cardioprotective function of inducible nitric oxide synthase and role of nitric oxide in myocardial ischemia and preconditioning: an overview of a decade of research. J Mol Cell Cardiol 33: 1897-1918, 2001.
4. CHEN H, SHEN WL, WANG XH, CHEN HZ, GU JZ, FU J, NI YF, GAO PJ, ZHU DL, HIGASHINO H: Paradoxically enhanced heart tolerance to ischaemia in type 1 diabetes and role of increased osmolarity. Clin Exp Pharmacol Physiol 33: 910-916, 2006.
5. CHENG X, XIA Z, LEO JM, PANG CC: The effect of N-acetylcysteine on cardiac contractility to dobutamine in rats with streptozotocin-induced diabetes. Eur J Pharmacol 519: 118-126, 2005. (Abstract)
6. EL-OMAR MM, LORD R, DRAPER NJ, SHAH AM: Role of nitric oxide in posthypoxic contractile dysfunction of diabetic cardiomyopathy. Eur J Heart Fail 5: 229-239, 2003 (Abstract)
7. FEUVRAY D, LOPASCHUK GD: Controversies on the sensitivity of the diabetic heart to ischemic injury: The sensitivity of the diabetic heart to ischemic injury is decreased. Cardiovas. Res 34: 113-120, 1997.
8. FORRAT R, SEBBAG L, WIENSPERGER A, GUIDOLLET J, DELAYE J, De LORGERIL M: Acute myocardial infarction in diabetic dogs with experimental diabetes. Cardiovasc Res 27: 1908-1912, 1993.
9. FERDINANDY P, SCHULZ R: Nitric oxide, superoxide, and peroxinitrite in myocardial ischemia-reperfusion injury and preconditioning. Br J Pharmacol 138: 532-543, 2003.
10. GALINANES M, FOWLER AG: Role of clinical pathologies in myocardial injury following ischaemia and reperfusion. Cardiovasc Res 61: 512-521, 2004.
11. HADOUR G, FERRERA R, SEBBAG L, FORRAT R, DELAYE J, De LORGERIL M: Improved myocardial tolerance to ischemia in the diabetic rabbit. J Mol Cell Cardiol 30: 1869-1875, 1998.
12. JAIN SK, LEVINESN. Elevated lipid peroxidation and vitamin E-quinone levels in heart ventricles of streptozotocin-treated diabetic rats. Free Radic Biol Med 18: 337-341, 1995.
13. KANNEL WB, MCGEE DL: Diabetes and cardiovascular risk factor. The Framingham Study. Circulation 59: 813, 1979.
14. KUCHARSKÁ J, GVOZDJAKOVÁ A, ŠTEFEK M, SOTNÍKOVÁ R, SUMBALOVA Z: Adaptive changes of antioxidant status in development of experimental diabetes. Bratisl Lek Listy 102: 515-519, 2001.
15. KUSAMA Y, HEARSE DJ, AVKIRAN M: Diabetes and susceptibility to reperfusion-induced ventricular arrhythmias. J Mol Cell Cardiol 24: 411-421, 1992.
16. LANG JK, GOHIL K, PACKER L: Simultaneous determination of tocopherols, ubuquinols, and ubiquinones in blood, plasma, tissue homogenates, and subcellular fractions. Anal Biochem 157: 106-116, 1986.
17. LECOUR S, MAUPOIL V, ZELLER M, LAUBRIET A, BRIOT T, ROCHETTE L: Levels of nitric oxide in the heart after experimental myocardial ischemia. J Cardiovasc Pharmacol 37: 55-63, 2001.
18. LIU Y, THORNTON JD, COHEN MV, DOWNEY JM, SCHAFFER SW: Streptozotocin - induced non-insulin dependent diabetes protects the heart from infarction. Circulation 88: 1273-1278, 1993.
19. MALMBERG K, RYDEN L: Myocardial infarction in patients with diabetes mellitus. Eur Heart J 9: 259-264, 1988.
20. MATEJÍKOVÁ J, KUCHARSKÁ J, PINTÉROVÁ M, RAVINGEROVÁ T: Involvement of mito K(ATP) channels and reactive oxygen species in antiarrhythmic effect of ischemic and pharmacological preconditioning of the rat heart. Physiol Res 56: 22P, 2007.
21. MELDRUM DR, CLEVELAND JC Jr, SHERIDAN BC, ROWLAND RT, BANERJEE A, HARKEN AH: Cardiac preconditioning with calcium: clinically accessible myocardial protection. J Thorac Cardiovasc Surg 112: 778-786, 1996.
22. PAULSON DJ: The diabetic heart is more sensitive to ischemic injury. Cardiovasc Res 34: 104-112, 1997.
23. PIERCE GN, RAMJIAWAN B, DHALLA NS, FERRARI R: Na(+)-H+ exchange in cardiac sarcolemmal vesicles isolated from diabetic rats. Am J Physiol Heart Circ Physiol 258: H255-H261, 1990.
24. PINTÉROVÁ M, PANCZA D, RAVINGEROVÁ T. The role of free radicals and mitochondrial K(ATP) channel modulations in the mechanisms of short-term cardioprotection in the rat heart. Physiol Res 55: 1P-2P, 2006.
25. SINGAL PK, BELLO-KLEIN A, FARAHMAND F, SANDHAWALIA V: Oxidative stress and functional deficit in diabetic cardiomyopathy. Adv Exp Med Biol 498: 213-220, 2001.
26. TOSAKI A, ENGELMAN DT, ENGELMAN RM, DAS DK: The evolution of diabetic response to ischemia/reperfusion and preconditioning in isolated working rat hearts. Cardiovasc Res 31: 526-536, 1996.
27. VEGH A, SZEKERES L, PARRATT JR: Preconditioning of the ischemic myocardium: involvement of the L-arginine nitric oxide pathway. Br J Pharmacol 107: 648-652, 1992.
28. VOLKOVOVÁ K, ZIEGELHÖFFER A, STARUCHOVÁ M, ONDREIČKA R: Vzt'ah medzi niektorými biochemickými ukazovatel'mi v krvi a v tkanive myokardu a toleranciou srdca k vápniku v rôznych štádiách experimentálneho diabetu. Cardiol 6: 152-157, 1997.
29. WALKER MJ, CURTIS MJ, HEARSE DJ, CAMPBELL RW, JANSE MJ, YELLON DM, COBBE SM, COKER SJ, HARNESS JB, HARRON DW, HIGGINS AJ, JULIAN DG, LAB MJ, MANNING AS, NORTHOVER BJ, PARRATT JR, RIEMERSMA RA, RIVA E, RUSSELL DC, SHERIDAN DJ, WINSLOW E, WOODWARD B: The Lambeth Conventions: guidelines for the study of arrhythmias in ischaemia infarction, and reperfusion. Cardiovasc Res 22: 447-455, 1988.