Irritancy and sensitization potential of glyoxylic acid

Journal of Immunotoxicology

Volumn 5, Issue 2, 2008, Pages 93-98

  Anderson, Stacey E ^a   Ham, Jason E ^a   Munson, Albert E ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

Hypersensitivity; Indoor air chemistry; LLNA; Respiratory sensitizers

Indexed keywords

CD45 ANTIGEN; DOMESTIC CHEMICAL; GLYOXYLIC ACID; IMMUNOGLOBULIN E; IRRITANT AGENT; VOLATILE ORGANIC COMPOUND;

AMBIENT AIR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; CHEMOSENSITIZATION; CONSUMER; CONTROLLED STUDY; FEMALE; IMMUNOGLOBULIN BLOOD LEVEL; INDOOR AIR POLLUTION; LOCAL LYMPH NODE ASSAY; LYMPHATIC DRAINAGE; MOUSE; NONHUMAN; OZONOLYSIS; PRIORITY JOURNAL;

ACUTE TOXICITY TESTS; AIR POLLUTION, INDOOR; ANIMALS; ANTIGENS, CD45; FEMALE; GLYOXYLATES; IMMUNOGLOBULIN E; IRRITANTS; LYMPH NODES; MICE; MICE, INBRED BALB C; T-LYMPHOCYTES;

EID: 45849139004     PISSN: 1547691X     EISSN: 1547691X     Source Type: Journal    
DOI: 10.1080/15476910802085681     Document Type: Article

References (20)

1. Anderson, S. E., Wells, J. R., Fedorowicz, A., Butterworth, L. F., Meade, B. J., and Munson A. E. 2007. Evaluation of the contact and respiratory sensitization potential of volatile organic compounds generated by simulated indoor air chemistry. Toxicol. Sci. 97:355-363.
2. Basketter, D. A., Lea, L. J., Dickens, A., Briggs, D., Pate, I., Dearman, R. J., and Kimber, I. 1999. A comparison of statistical approaches to the derivation of EC3 values from local lymph node assay dose responses. J. Appl. Toxicol. 19:261-266.
3. Doyle, M., Sexton, K. G., Jeffries, H., Bridge, K., and Jaspers, I. 2004. Effects of 1,3-butadiene, isoprene, and their photochemical degradation products on human lung cells. Environ. Health Perspect. 112:1488-1495.
4. Grosjean, E., Williams, E. L., and Grosjean, D. 1994. Atmospheric chemistry of acrolein. Sci. Total Environ. 153:195-202.
5. Jarvis, J., Seed, M. J., Elton, R., Sawyer, L., and Agius, R. 2005. Relationship between chemical structure and the occupational asthma hazard of low molecular weight organic compounds. Occup. Environ. Med. 62:243-250.
6. Kammeyer, A., Eggelte, T. A., Overmars, H., Bootsma, A., Bos, J. D., and Teunissen, M. B. 2001. Oxidative breakdown and conversion of urocanic acid isomers by hydroxyl radical generating systems. Biochim. Biophys. Acta 1526:277-285.
7. Lee, Y. N., and Hallock, K. 1995. Atmospheric carbonyl compounds at a rural southeastern United States site. J. Geophys. Res. Atmos. 100:25933-25944.
8. Manetz, T. S., and Meade, B. J. 1999. Development of a flow cytometry assay for the identification and differentiation of chemicals with the potential to elicit irritation, IgE-mediated, or T-cell-mediated hypersensitivity responses. Toxicol. Sci. 48:206-217.
9. Nair, B. 1997. Final report on the safety assessment of formic acid. Int. J. Toxicol. 16:221-234.
10. NIEHS; National Institute of Environmental Health Sciences. 1999. The Murine Local Lymph Node Assay: A Test Method for Assessing the Allergic Contact Dermatitis Potential of Chemicals/Compounds. Fed. Reg. 64:14006-14007.
11. NIOSH; National Institute for Occupational Safety and Health. 1983. National Occupational Exposure Survey 1981-1983. Washington, DC.
12. Rohr, A. C., Weschler, C. J., Koutrakis, P., and Spengler, J. D. 2003. Generation and quantification of ultrafine particles through terpene/ozone reaction in a chamber setting. Aerosol Sci. Technol. 37:65-78.
13. Rohrl, A., and Lammel, G. 2001. Low-molecular weight dicarboxylic acids and glyoxylic acid: Seasonal and air mass characteristics. Environ. Sci. Technol. 35:95-101.
14. Strøm-Tejsen, P., Weschler, C. J., Wargocki, P., Myków, D., and Zarzycka, J. 2007. The influence of ozone on self-evaluation of symptoms in a simulated aircraft cabin. J. Exposure Sci. Environ. Epidemiol. doi:10.1038/sj.jes.7500586.
15. US EPA; Environmental Protection Agency. 1990. 1990 HPV Challenge Program Chemical List. Environmental Protection Agency; Washington, DC.
16. US EPA; Environmental Protection Agency. 1994. Chemical Summary for Acrylic Acid. Office of Pollution Prevention and Toxics; Washington, DC.
17. Weschler, C. J. 2006. Ozone's impact on public health: Contributions from indoor exposures to ozone and products of ozone-initiated chemistry. Environ. Health Perspect. 114:1489-1496.
18. Weschler, C. J., Wisthaler, A., Cowlin, S., Tamás, G., Strøm-Tejsen, P., Hodgson, A. T., Destaillats, H., Herrington, J., Zhang, J., and Nazaroff, W. W. 2007. Ozone-initiated chemistry in an occupied simulated aircraft cabin. Environ. Sci. Technol. 41:6177-6184.
19. Wilkins, C. K., Clausen, P. A., Wolkoff, P., Larsen, S. T., Hammer, M., Larsen, K., Hansen, V., and Nielsen, G. D. 2001. Formation of strong airway irritants in mixtures of isoprene/ozone and isoprene/ozone/nitrogen dioxide. Environ. Health Perspect. 109:937-941.
20. Woolhiser, M. R., Hayes, B. B., and Meade, B. J. 1998. A combined murine local lymph node and irritancy assay to predict sensitization and irritancy potential of chemicals. Toxicol. Meth. 8:245-256.