Synthesis and in-vitro antifungal activity of 6-substituted-phenyl-2- {[(4′-substituted phenyl-5′-thioxo)-1,2,4-triazol-3-yl]-methyl}-2,3, 4,5-tetrahydropyridazin-3-one derivatives

Acta Poloniae Pharmaceutica - Drug Research

Volumn 65, Issue 2, 2008, Pages 223-228

  Siddiqui, Anees A ^a   Ahamad, Syed Rizwan ^a   Mir, Mohammed Shehroz ^a   Hussain, Syed Akhtar ^b   Raish, Mohammed ^b   Kaur, Ravindra ^c  

^a HAMDARD UNIVERSITY   (India)

^b JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

^c MAULANA AZAD MEDICAL COLLEGE   (India)

Author keywords

1,2,4 triazole; Antifungal activity

Indexed keywords

1,2,4 TRIAZOLE DERIVATIVE; 6 (4' CHLOROBENZENE) 2 [[(4' 4 CHLOROPHENYL 5' THIOXO) 1,2,4 TRIAZOL 3 YL]METHYL] 2,3,4,5 TETRAHYDROPYRIDAZIN 3 ONE; ANTIFUNGAL AGENT; AROMATIC COMPOUND; AROMATIC HYDROCARBON; BENZENE; BENZENE DERIVATIVE; CHLORINE DERIVATIVE; PYRIDAZINE DERIVATIVE; VORICONAZOLE;

ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS FLAVUS; ASPERGILLUS FUMIGATUS; ASPERGILLUS NIGER; CANDIDA ALBICANS; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PENICILLIUM CITRINUM; REACTION ANALYSIS; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION; TRICHOPHYTON RUBRUM;

ANTIFUNGAL AGENTS; MICROBIAL SENSITIVITY TESTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 45849132383     PISSN: 00016837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Holla B. S., Golsalves R., Shenoy, S.: Farmaco 53, 574 (1998).
2. Ersan S., Nacak S., Berkem R.: Farmaco 53, 773 (1998).
3. Yuksek H., Demirbas A., Ikizler A., Johansson C.B., Celik C., Ikizler A.A.: Arzneim.-Forsch. Drug Res. 47, 405 (1997).
4. Ikizler A.A., Ucar F., Demirbas N., Yasa I., Ikizler A., Genzer T.: Indian J. Heterocycl. Chem. 61, 271 (1999).
5. Tazkoparan B., Gokhan N., Aktay G., Yesilada E., Ertan M.: Eur. J. Med. Chem. 34, 743 (2000).
6. Zitouni G.T., Kaplancikli Z.A., Erol K., Kilic F.S.: Farmaco 54, 218 (1999).
7. Demirbas N., Ugurluoglu D.: Bioorg. Med. Chem. 10, 3717 (2002).
8. Emilsson H., Salendar H., Gaarder J.: Eur. J. Med. Chem. 21, 333 (1985).
9. Kritsanida M., Mouroutsou A., Marakos P., et al.: Farmaco 57, 253 (2002).
10. Collin X., Sauleu A., Coulon J.: Bioorg. Med. Chem. 13, 2601 (2003).
11. Al-Soud Y.A., Al-Dweri M.N., Al-Masoudi N. A.: Farmaco 59, 775 (2004).
12. th ed. Approved standard, fourth ed., NCCLS Document M7-A4. National Committee for Clinical and Laboratory Standards, Villanova, PA, USA 1997.
13. National Committee for Clinical Laboratory Standards. Reference methods for broth dilution antifungal susceptibility tests for yeasts. Approved standard. Document M 27-A. National Committee for Clinical and Laboratory Standards. Wayne, PA, USA 1997.
14. National Committee for Clinical Laboratory Standards. Reference methods for broth dilution antifungal susceptibility testing for conidium forming filamentous fungi. Proposed standard. Document M7-A5.National Committee for Clinical and Laboratory Standards. Wayne, PA, USA 2000.