Synthesis and antimicrobial activity of n-[(α-methyl)benzylidene]-(3-substituted-1,2,4-triazol-5-yl-thio) acetohydrazides

Farmaco

Volumn 53, Issue 12, 1998, Pages 773-776

  Ersan, Seyhan ^a   Nacak, Sultan ^a   Berkem, Rukiye ^b  

^a GAZI UNIVERSITY   (Turkey)

^b ANKARA TRAINING AND RESEARCH HOSPITAL   (Turkey)

Author keywords

Antibacterial agents; Antifungal agents; Substituted triazole derivatives

Indexed keywords

ACETOHYDRAZIDE; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT;

ANTIMICROBIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; NONHUMAN;

ANTI-BACTERIAL AGENTS; BACTERIA; BENZYLIDENE COMPOUNDS; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HYDRAZINES; MICROBIAL SENSITIVITY TESTS; TRIAZOLES;

EID: 0032583456     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(98)00095-0     Document Type: Article

References (15)

1. Shah H., Mhasalkar M.Y., Varaya N.A., Bellare R.A Disubstitued-5-carboxymethylthio-4H-1,2,4-triazoles as possible antiviral agents. Indian J. Chem. 5:1967;391-393. Ref. C.A. 68 (1968) 10147.
2. Lehmkuhl F., Witkowsky J.T., Robins R.K. Synthesis of 1,2,3-triazole nucleosides via the acid-catalysed fusion procedure. J. Heterocycl. Chem. 9:1972;1195-1201.
3. Hassan E., Al-Ashmawi M.I., Abdel-Fattah B. Synthesis and antimicrobial testing of certain oxadiazoline and triazole derivatives. Pharmazie. 38:1983;833-835.
4. Eweisa N.F., Bahajaj A.A., Elsherbini E.A. Synthesis of heterocycles. Part VI. Synthesis and antimicrobial activity of some 4-amino-5-aryl-1,2,4-triazole-3-thiones and their derivatives. J. Heterocycl. Chem. 23:1986;1451-1458.
5. Ainsworth C., Easton N.R., Livezey M. et al. The anticonvulsant activity of 1,2,4-triazoles. J. Med. Pharm. Chem. 5:1962;383-389.
6. Invidiata F.P., Simoni D. 3,6-Disubstituted-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles: synthesis, antimicrobial and antiviral activity II. Farmaco. 51:1996;659-664.
7. Hancock H.G., Weete J.D. Effects of triazoles on fungi. Pestic. Biochem. Physiol. 24:1985;395-405.
8. Sancholle M., Weete J.D., Montant C. Effects of triazoles on fungi: I. growth and cellular permeability. Pestic. Biochem. Physiol. 21:1984;31-44.
9. Tanio T., Ichise K., Nakajima T., Okuda T. In vivo efficacy of SM-8668 (Sch 39304) a new oral triazole antifungal agent. Antimicrob. Agents Chemother. 34:1990;980-984.
10. Ersan S., Nacak S., Berkem R., Özden T. Synthesis and antimicrobial activity of 2-[α(-methylbenzylidene)hydrazino]benzoxazoles. Arzneimittel-Forsch. Drug Res. 47:1997;963-965.
11. Freund M., Meinecke C. Über derivate des thiobiazolins. Chem. Ber. 29:1896;2511-2517.
12. Gürsoy A., Demirayak Ş., Cesur Z., Reich G., Ötük G. Synthesis of some new hydrazide-hydrazones, thiosemicarbazides, thiadiazoles, triazoles and their derivatives as possible antimicrobials. Pharmazie. 45:1990;246-250.
13. Isenberg H.D. Clinical Microbiology Procedures Handbook. 1:1992;American Society for Microbiology, Washington, DC.
14. Balows A., Hauser W.J., Herrmann K.L., Isenberg H.D., Shadomy H.J. Manual of Microbiology. 5th ed. 1991;1105-1116 American Society for Microbiology, Washington, DC.
15. Murray P.P., Baron E.J., Pfaller M.A., Tenover F.C., Yolken R.H. Manual of Clinical Microbiology. 6th ed. 1995;1405-1414 American Society for Microbiology, Washington, DC.