A cytosolic iron chaperone that delivers iron to ferritin

Science

Volumn 320, Issue 5880, 2008, Pages 1207-1210

  Shi, Haifeng ^a   Bencze, Krisztina Z ^b   Stemmler, Timothy L ^b   Philpott, Caroline C ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; COMPLEMENTARY DNA; COPPER; FERRIC CHLORIDE; FERRITIN; FRATAXIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; IRON; IRON 55; NICKEL; PCBP1 PROTEIN; RNA BINDING PROTEIN; HYBRID PROTEIN; PCBP1 PROTEIN, HUMAN;

IRON; MAMMAL; PROTEIN; YEAST;

ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BIOSYNTHESIS; CONTROLLED STUDY; CYTOSOL; FRIEDREICH ATAXIA; HUMAN; IRON STORAGE; LIVER; MITOCHONDRION; NEUROLOGIC DISEASE; NONHUMAN; PLASMID; PRIORITY JOURNAL; REPORTER GENE; YEAST; CELL CULTURE; GENETICS; METABOLISM; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE;

ANIMALIA; MAMMALIA;

CYTOSOL; FERRITINS; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS; HUMANS; IRON; MOLECULAR CHAPERONES; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; TUMOR CELLS, CULTURED;

EID: 45849123222     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1157643     Document Type: Article

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20. The authors thank S. Liebhaber for the PCBP1 plasmid, protein samples, and helpful discussions; H. Levin for helpful discussions and ferritin plasmids; P. Ponka for salicylaldehyde isonicotinoyl hydrazone; and T. Rouault for helpful discussions, cell lines, and the IRP2 antibody. These studies were supported by the Intramural Research Program of the National Institute of Diabetes and Digestive and Kidney Diseases (H.S. and C.C.P.) and by NIH R01 DK068139 (K.Z.B. and T.L.S.).