Life-Threatening Dextromethorphan Intoxication Associated with Interaction with Amitriptyline in a Poor CYP2D6 Metabolizer: A Single Case Re-Exposure Study

Journal of Pain and Symptom Management

Volumn 36, Issue 1, 2008, Pages 92-96

  Forget, Patrice ^a   le Polain de Waroux, Bernard ^a   Wallemacq, Pierre ^a   Gala, Jean Luc ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

amitriptyline; CYP2D6; Dextromethorphan; interaction

Indexed keywords

ACATAR; ACETYLSALICYLIC ACID; AMITRIPTYLINE; BISACODYL; CLONAZEPAM; CYTOCHROME P450 2D6; DEXTROMETHORPHAN; DOCUSATE SODIUM; GABAPENTIN; GLUCURONOSYLTRANSFERASE; HYDROMORPHONE; INSULIN; ISOPHANE INSULIN; PARACETAMOL; SEDERGINE;

ADULT; ANALGESIC ACTIVITY; ANAMNESIS; ARTICLE; CASE REPORT; CATTLE DISEASE; CLINICAL FEATURE; CONTROLLED STUDY; DIABETES MELLITUS; DNA POLYMORPHISM; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG INTOXICATION; DRUG METABOLISM; DRUG UPTAKE; DRUG WITHDRAWAL; EMERGENCY CARE; GENE MUTATION; GENETIC VARIABILITY; GENOTYPE; HOSPITAL ADMISSION; HUMAN; MALE; NEUROPATHIC PAIN; PHENOTYPE; POLYMERASE CHAIN REACTION; SOMNOLENCE;

AMITRIPTYLINE; ANTIDEPRESSIVE AGENTS, TRICYCLIC; ANTITUSSIVE AGENTS; COMA; CYTOCHROME P-450 CYP2D6; DEXTROMETHORPHAN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED;

EID: 45849113221     PISSN: 08853924     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpainsymman.2007.09.006     Document Type: Article

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