Quantification of electroporative uptake kinetics and electric field heterogeneity effects in cells

Biophysical Journal

Volumn 94, Issue 12, 2008, Pages 5018-5027

  Kennedy, S M ^a   Ji, Z ^a   Hedstrom, J C ^a   Booske, J H ^a   Hagness, S C ^a  

^a University of Wisconsin Madison   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOPOLYMER;

ARTICLE; BIOLOGICAL MODEL; CELL MEMBRANE; CELL STRAIN HL 60; COMPUTER SIMULATION; ELECTROMAGNETIC FIELD; ELECTROPORATION; FLUORESCENCE MICROSCOPY; HUMAN; KINETICS; METABOLIC CLEARANCE RATE; METABOLISM; METHODOLOGY; RADIATION EXPOSURE;

BIOPOLYMERS; CELL MEMBRANE; COMPUTER SIMULATION; ELECTROMAGNETIC FIELDS; ELECTROPORATION; HL-60 CELLS; HUMANS; KINETICS; METABOLIC CLEARANCE RATE; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL;

EID: 45849105579     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1529/biophysj.106.103218     Document Type: Article

References (41)

1. Weaver, J. C. 2000. Electroporation of cells and tissues. IEEE Trans. Plasma Sci. 28:24-33.
2. Neumann, E., A. E. Sowers, and C. A. Jordan, editors. 1989. Electroporation and Electrofusion in Cell Biology. Plenum Press, New York.
3. Zimmerman, U., and G. A. Neil. 1996. Electromanipulation of Cells. CRC Press, Boca Raton, FL.
4. Chang, C. C., B. M. Chassy, J. A. Saunders, and A. E. Sowers. Eds. 1992. Guide to Electroporation and Electrofusion. Academic Press, San Diego.
5. Rubinsky, B. 2007. Irreversible electroporation in medicine. Technol. Cancer Res. Treat. 6:255-259.
6. Esser, A. T., K. C. Smith, T. R. Gowrishankar, and J. C. Weaver. 2007. Towards sold tumor treatment by irreversible electroporation: intrinsic redistribution of fields and currents in tissue. Technol. Cancer Res. Treat. 6:261-273.
7. Rubinsky, B., G. Onik, and P. Mikus. 2007. Irreversible electroporation: a new ablation modality - clinical implications. Technol. Cancer Res. Treat. 6:37-48.
8. Nuccitelli, R., U. Pliquett, X. Chen, W. Ford, R. J. Swanson, S. J. Beebe, J. F. Kold, and K. H. Schoenbach. 2006. Nanosecond pulsed electric fields cause melanomas to self-destruct. Biochem. Biophys. Res. Commun. 343:351-360.
9. Beebe, S. J., P. M. Fox, L. J. Rec, K. Somers, R. H. Stark, and K. H. Schoenbach. 2002. Nanosecond pulsed electric field (nsPEF) effects on cells and tissues: apoptosis induction and tumor growth inhibition. IEEE Trans. Plasma Sci. 30:286-292.
10. Beebe, S. J., P. M. Fox, L. J. Rec, E. L. Willis, and K. H. Schoenbach. 2003. Nanosecond, high-intensity pulsed electric fields induce apoptosis in human cells. FASEB J. 17:1493-1495.
11. Beebe, S. J., J. White, P. F. Blackmore, Y. Deng, K. Somers, and K. H. Schoenbach. 2003. Nanosecond pulsed electric fields modulate cell function through intracellular signal transduction mechanisms. Physiol. Meas. 25:1077-1093.
12. Andre, F. L., and M. Mir. 2004. DNA electrotransfer: its principles and an updated review of its therapeutic applications. Gene Ther. 11:S33-S42.
13. Nishi, T., K. Yoshizato, S. Yamashiro, H. Takeshima, K. Sato, K. Hamada, I. Kitamura, T. Yoshimura, H. Saya, J. Kuratsu, and Y. Ushio. 1996. High-efficiency in vivo gene transfer using intraarterial plasmid DNA injection following in vivo electroporation. Cancer Res. 56:1050-1055.
14. Hu, Q., V. Sridhara, R. P. Joshi, J. F. Kolb, and K. H. Schoenbach. 2006. Molecular dynamics analysis of high electric pulse effects on bilayer membranes containing DPPC and DPPs. IEEE Trans. Plasma Sci. 34:1405-1411.
15. Wells, D. J. 2004. Gene therapy progress and prospects: electroporation and other physical methods. Gene Ther. 11:1363-1369.
16. Wu, C.-M., M. W. Lin, J. T. Cheng, Y. M. Wang, Y. W. Huang, W. Z. Sun, and C. R. Lin. 2004. Regulated, electroporation-mediated delivery of pro-opiomelanocortin gene suppresses chronic constriction injury-induced neuropathic pain in rats. Gene Ther. 11:933-940.
17. Heller, R. 2002. The development of electroporation. Science. 295:277.
18. Gowrishankar, T. R., and J. C. Weaver. 2006. Electrical behavior and pore accumulation in a multicellular model for conventional and supra- electroporation. Biochem. Biophys. Res. Commun. 349:643-653.
19. Vasilkoski, J., A. T. Esser, T. R. Gowrishankar, and J. C. Weaver. 2006. Membrane electroporation: the absolute rate equation and nanosecond time scale pore creation. Phys. Rev. E. 74:021904.
20. Tieleman, D. P. 2006. Computer simulations of transport through membranes: passable diffusion, pores, channels and transporters. Clin. Exp. Pharmacol. Physiol. 33:893-903.
21. Pavlin, M., V. Leben, and D. Miklavcic. 2007. Electroporation in dense cell suspension - Theoretical and experimental analysis of ion diffusion and cell permeabilization. Biochim. Biophys. Acta. 1770:12-23.
22. Joshi, R. P., V. Sridhara, and K. H. Schoenbach. 2006. Microscopic calculations of local lipid membrane permitivities and diffusion coefficients for application to electroporation analyses. Biochem. Biophys. Res. Commun. 348:643-648.
23. Ji, Z., S. M. Kennedy, J. H. Booske, and S. C. Hagness. 2006. Experimental studies of persistent poration dynamics of cell membranes induced by electric pulses. IEEE Trans. Plasma Sci. 34:1416-1424.
24. Fletcher, G. G., F. E. Rossetto, J. D. Turnbeull, and E. Nielboer. 1994. Toxicity, uptake and mutagenicity of particulate and soluble nickel compounds. Environ. Health Perspect. 102:69-79.
25. Orlowski, S., J. Belehradek, Jr., C. Paoletti, and L. M. Mir. 1988. Transient electropermeabilization of cells in culture. Increase of the cytotoxicity of anticancer drugs. Biochem. Pharmacol. 37:4727-4733.
26. Müller, K. J., V. L. Sukhorukov, and U. Zimmermann. 2001. Reversible electropermeabilization of mammalian cells by high-intensity, ultra-short pulses of submicrosecond duration. J. Membr. Biol. 184:161-170.
27. Joshi, R. P., and K. H. Schoenbach. 2000. Electroporation dynamics in biological cells subjected to ultrafast electrical pulses: A numerical simulation study. Phys. Rev. E. 62:1025-1033.
28. Joshi, R. P., Q. Hu, and K. H. Schoenbach. 2003. Dynamic modeling of cellular response to short-duration, high-intensity electric fields. IEEE Trans. Dielectrics Electr. Insul. 10:778-787.
29. Deng, J., K. H. Schoenbach, E. S. Buescher, P. S. Hair, P. M. Fox, and S. J. Beebe. 2003. The effects of intense submicrosecond electrical pulses on cells. Biophys. J. 84:2709-2714.
30. Demaurex, N., and C. Distelhorst. 2003. Apoptosis - the calcium connection. Science. 300:135-139.
31. Rols, M.-P., and J. Teissié. 1990. Electropermeabilization of mammalian cells. Biophys. J. 58:1089-1098.
32. Tekle, E., R. D. Astumian, and P. B. Chock. 1994. Selective and asymmetric molecular transport across electroporated cell membranes. Proc. Natl. Acad. Sci. USA. 91:11512-11516.
33. Gabriel, B., and J. Teissié. 1997. Direct observation in the millisecond time range of fluorescent molecule asymmetrical interaction with the electropermeabilized cell membrane. Biophys. J. 73:2630-2637.
34. Gabriel, B., and J. Teissié. 1999. Time course of mammalian cell electropermeabilization observed by millisecond imaging of membrane property changes during the pulse. Biophys. J. 76:2158-2165.
35. Tekle, E., R. D. Astumian, W. A. Friauf, and P. B. Chock. 2001. Asymmetric pore distribution and loss of membrane lipid in electroporated DOPC vesicles. Biophys. J. 81:960-968.
36. Golzio, M., M. P. Rols, and J. Teissié. 2004. In vitro electric field-mediated permeabilization, gene transfer, and expression. Methods. 33:126-135.
37. Phez, E., C. Faurie, M. Golzio, J. Teissié, and M.-P. Rols. 2005. New insights in the visualization of membrane permeabilization and DNA/membrane interaction of cells submitted to electric pulses. Biochim. Biophys. Acta. 1724:248-254.
38. Vernier, P. T., Y. Sun, and M. A. Gundersen. 2006. Nanoelectropulse- driven membrane perturbation and small molecule permeabilization. BMC Cell Biol. 7:37.
39. Agarwal, A. K., S. S. Sridharamurthy, D. J. Beebe, and H. Jiang. 2005. Programmable autonomous micromixers and micropumps. J. Microelectromech. Syst. 14:1409-1421.
40. Microfab NI 100 sulfamate nickel for semiconductor processing technical data sheet. 2002. Enthone Incorporated, West Haven, CT.
41. Etchant/Metal compatibility chart. 2005. Transene Company, Danvers, MA.