Phase I trial of docetaxel and thalidomide: A regimen based on metronomic therapeutic principles

Investigational New Drugs

Volumn 26, Issue 4, 2008, Pages 355-362

  Sanborn, Sharon L ^a   Cooney, Matthew M ^a   Dowlati, Afshin ^a   Brell, Joanna M ^a   Krishnamurthi, Smitha ^a   Gibbons, Joseph ^a   Bokar, Joseph A ^a   Nock, Charles ^a   Ness, Anne ^a   Remick, Scot C ^b  

^a UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^b WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

Angiogenesis; Docetaxel; Metronomic; Phase I; Thalidomide

Indexed keywords

BISACODYL; DOCETAXEL; THALIDOMIDE; WARFARIN;

ADULT; ADVANCED CANCER; AGED; ALOPECIA; ANEMIA; ANOREXIA; ANTINEOPLASTIC ACTIVITY; ARTICLE; BILE DUCT CARCINOMA; BRADYCARDIA; BREAST CARCINOMA; CARCINOID; CARDIOVASCULAR DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; COLON CANCER; COMBINATION CHEMOTHERAPY; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE COURSE; DIZZINESS; DRUG DOSE ESCALATION; DRUG DOSE REDUCTION; DRUG DOSE REGIMEN; DRUG SAFETY; DYSPNEA; EDEMA; ESOPHAGUS CANCER; EYE DISEASE; FATIGUE; FEMALE; FEVER; GASTROINTESTINAL STROMAL TUMOR; HEAD AND NECK CANCER; HEART INFARCTION; HOT FLUSH; HUMAN; HYPERBILIRUBINEMIA; HYPERGLYCEMIA; HYPOALBUMINEMIA; HYPOCALCEMIA; HYPOGLYCEMIA; HYPOMAGNESEMIA; HYPONATREMIA; HYPOPHOSPHATEMIA; INSOMNIA; KIDNEY CARCINOMA; LEUKOPENIA; LUNG CANCER; LYMPHOCYTOPENIA; MALE; MAXIMUM TOLERATED DOSE; MELANOMA; MOOD CHANGE; MUCOSA INFLAMMATION; NAUSEA; NEUROPATHY; NEUTROPENIA; NIGHT SWEAT; PAIN; PANCREAS CANCER; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; PROPHYLAXIS; PROSTATE CANCER; RASH; SARCOMA; SIDE EFFECT; SOLID TUMOR; STOMACH CANCER; SYNCOPE; TASTE DISORDER; THROMBOCYTOPENIA; THROMBOEMBOLISM; THYMOMA; THYROID CANCER; TRANSITIONAL CELL CARCINOMA; TREATMENT DURATION; TREATMENT RESPONSE; URETER CARCINOMA; VATER PAPILLA CARCINOMA; VOMITING; WEIGHT REDUCTION;

ADULT; AGED; ANGIOGENESIS INHIBITORS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; DISEASE PROGRESSION; DISEASE-FREE SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MALE; MAXIMUM TOLERATED DOSE; MIDDLE AGED; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; PACLITAXEL; THALIDOMIDE;

EID: 45849100875     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10637-008-9137-0     Document Type: Article

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