Determining normal variability in a developmental neurotoxicity test A report from the ILSI Research Foundation/Risk Science Institute expert working group on neurodevelopmental endpoints

Neurotoxicology and Teratology

Volumn 30, Issue 4, 2008, Pages 288-325

  Raffaele, Kathleen C ^a   Fisher Jr , J Edward ^b   Hancock, Scott ^c   Hazelden, Keith ^d   Sobrian, Sonya K ^e  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c HEALTH CANADA   (Canada)

^d Department of Safety Assessment ^*  (United States)

^e HOWARD UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Developmental neurotoxicity testing; DNT; Regulatory testing; Variability in DNT testing

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL CARE; AUDITORY STIMULATION; CIRCADIAN RHYTHM; HABITUATION; HEALTH CARE ORGANIZATION; INSTRUMENTAL CONDITIONING; LEARNING; LITTER SIZE; MEDICAL RESEARCH; MEMORY; MOTOR ACTIVITY; NEUROTOXICITY; NONHUMAN; POSTNATAL DEVELOPMENT; PRENATAL DEVELOPMENT; PRIORITY JOURNAL; REVIEW; STARTLE REFLEX; TOXICITY TESTING;

ACOUSTIC STIMULATION; ANIMALS; DATA COLLECTION; HUMANS; MODELS, ANIMAL; NERVOUS SYSTEM DISEASES; REFERENCE STANDARDS; RESEARCH DESIGN; STARTLE REACTION; TOXICITY TESTS;

EID: 45849090375     PISSN: 08920362     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ntt.2007.12.009     Document Type: Review

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