Marked variation in responses to long-term nitric oxide inhibition during pregnancy in outbred rats from two different colonies

American Journal of Obstetrics and Gynecology

Volumn 184, Issue 4, 2001, Pages 686-693

  Buhimschi, I A ^a   Shi, S Q ^a   Saade, G R ^a   Garfield, R E ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Hypertension; Intrauterine growth restriction; Nitric oxide; Preeclampsia; Pregnancy

Indexed keywords

N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; FETUS OUTCOME; FETUS WEIGHT; GENETIC ANALYSIS; INTRAUTERINE GROWTH RETARDATION; MATERNAL HYPERTENSION; NONHUMAN; OSMOTIC MINIPUMP; PREECLAMPSIA; PREGNANCY; PRIORITY JOURNAL; PROTEINURIA; RAT STRAIN; SYSTOLIC BLOOD PRESSURE;

EID: 0035085008     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1067/mob.2001.110448     Document Type: Article

References (20)

1. Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage
2. Inhibition of nitric oxide synthesis in rats during pregnancy produces signs similar to those of preeclampsia
3. Prolonged blockade of nitric oxide synthesis in gravid rats produces sustained hypertension, proteinuria, thrombocytopenia, and intrauterine growth retardation
4. Study on the morphological changes in the placenta of rats administered nitric oxide synthase inhibitor
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13. Hypertensive response to chronic NO synthase inhibition is different in Sprague-Dawley rats from two suppliers
14. Control of vascular reactivity in pregnancy
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16. Prevention of preeclampsia: Is it possible?
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20. Genetic analysis of inherited hypertension in the rat