Interaction of the molecular chaperone HtpG with uroporphyrinogen decarboxylase in the cyanobacterium Synechococcus elongatus PCC 7942

Bioscience, Biotechnology and Biochemistry

Volumn 72, Issue 5, 2008, Pages 1394-1397

  Saito, Masakazu ^a   Watanabe, Satoru ^b   Yoshikawa, Hirofumi ^b   Nakamoto, Hitoshi ^a  

^a SAITAMA UNIVERSITY   (Japan)

^b TOKYO UNIVERSITY OF AGRICULTURE   (Japan)

Author keywords

Cyanobacterium; Hsp90; HtpG; Tetrapyrrole; Uroporphyrinogen decarboxylase

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; ENZYME ACTIVITY; FLOW INTERACTIONS; FOOD ADDITIVES; HEMOGLOBIN; PORPHYRINS;

BIOCHEMICAL STUDIES; COMPLEX FORMATIONS; CYANOBACTERIUM; DECARBOXYLASE; IN-VITRO; IN-VIVO; MOLECULAR CHAPERONES; SYNECHOCOCCUS; TETRAPYRROLE BIOSYNTHESIS;

BIOCHEMICAL ENGINEERING;

BACTERIAL PROTEIN; HEAT SHOCK PROTEIN 90; HTPG PROTEIN, BACTERIA; PEPTIDE; TETRAPYRROLE DERIVATIVE; UROPORPHYRINOGEN DECARBOXYLASE;

ARTICLE; CLASSIFICATION; ENZYMOLOGY; METABOLISM; PROTEIN BINDING; SYNECHOCOCCUS;

BACTERIAL PROTEINS; HSP90 HEAT-SHOCK PROTEINS; PEPTIDES; PROTEIN BINDING; SYNECHOCOCCUS; TETRAPYRROLES; UROPORPHYRINOGEN DECARBOXYLASE;

SYNECHOCOCCUS ELONGATUS; SYNECHOCOCCUS ELONGATUS PCC 6301; SYNECHOCOCCUS ELONGATUS PCC 7942;

EID: 45749150289     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.80093     Document Type: Article

References (19)

1. Elder, G. H., and Roberts, A. G., Uroporphyrinogen decarboxylase. J. Bioenerg. Biomembr., 27, 207-214 (1995).
2. Jones, R. M., and Jordan, P. M., Purification and properties of the uroporphyrinogen decarboxylase from Rhodobacter sphaeroides. Biochem. J., 293, 703-712 (1993).
3. de Verneuil, H., Sassa, S., and Kappas, A., Purification and properties of uroporphyrinogen decarboxylase from human erythrocytes: a single enzyme catalyzing the four sequential decarboxylations of uroporphyrinogens I and III. J. Biol. Chem., 258, 2454-2460 (1983).
4. Kiel, J. A., Ten Berge, A. M., and Venema, G., Nucleotide sequence of the Synechococcus sp. PCC7942 hemE gene encoding the homologue of mammalian uroporphyrinogen decarboxylase. DNA Seq., 2, 415-418 (1992).
5. Pearl, L. H., and Prodromou, C., Structure and mechanism of the Hsp90 molecular chaperone machinery. Annu. Rev. Biochem., 75, 271-294 (2006).
6. Wiech, H., Buchner, J., Zimmermann, R., and Jakob, U., Hsp90 chaperones protein folding in vitro. Nature, 358, 169-170 (1992).
7. Freeman, B. C., and Morimoto, R. I., The human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj-1 have distinct roles in recognition of a nonnative protein and protein refolding. EMBO J., 15, 2969-2979 (1996).
8. Nathan, D. F., Vos, M. H., and Lindquist, S., In vivo functions of the Saccharomyces cerevisiae Hsp90 chaperone. Proc. Natl. Acad. Sci. USA, 94, 12949-12956 (1997).
9. Pratt, W. B., and Welsh, M. J., Chaperone functions of the heat shock proteins associated with steroid receptors. Semin. Cell Biol., 5, 83-93 (1994).
10. Jakob, U., Meyer, I., Bugl, H., Andre, S., Bardwell, J. C., and Buchner, J., Structural organization of procaryotic and eucaryotic Hsp90: influence of divalent cations on structure and function. J. Biol. Chem., 270, 14412-14419 (1995).
11. Spence, J., and Georgopoulos, C., Purification and properties of the Escherichia coli heat shock protein, HtpG. J. Biol. Chem., 264, 4398-4403 (1989).
12. Bardwell, J. C., and Craig, E. A., Ancient heat shock gene is dispensable. J. Bacteriol., 170, 2977-2983 (1988).
13. Versteeg, S., Mogk, A., and Schumann, W., The Bacillus subtilis htpG gene is not involved in thermal stress management. Mol. Gen. Genet., 261, 582-588 (1999).
14. Tanaka, N., and Nakamoto, H., HtpG is essential for the thermal stress management in cyanobacteria. FEBS Lett., 458, 117-123 (1999).
15. Hossain, M. M., and Nakamoto, H., HtpG plays a role in cold acclimation in cyanobacteria. Curr. Microbiol., 44, 291-296 (2002).
16. Hossain, M. M., and Nakamoto, H., Role for the cyanobacterial HtpG in protection from oxidative stress. Curr. Microbiol., 46, 70-76 (2003).
17. Watanabe, S., Kobayashi, T., Saito, M., Sato, M., Nimura-Matsune, K., Chibazakura, T., Taketani, S., Nakamoto, H., and Yoshikawa, H., Studies on the role of HtpG in the tetrapyrrole biosynthesis pathway of the cyanobacterium Synechococcus elongatus PCC 7942. Biochem. Biophys. Res. Commun., 352, 36-41 (2007).
18. Whitby, F. G., Phillips, J. D., Kushner, J. P., and Hill, C. P., Crystal structure of human uroporphyrinogen decarboxylase. EMBO J., 17, 2463-2471 (1998).
19. Martins, B. M., Grimm, B., Mock, H. P., Huber, R., and Messerschmid, A., Crystal structure and substrate binding modeling of the uroporphyrinogen-III decarboxylase from Nicotiana tabacum: implications for the catalytic mechanism. J. Biol. Chem., 276, 44108-44116 (2001).