Antithrombogenicity of hydromer's polymeric formula F202™ immobilized on polyurethane and electropolished stainless steel

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 86, Issue 1, 2008, Pages 136-144

  Vicario, Pasquale P ^a   Lu, Zichun ^a   Wang, Zheng ^a   Merritt, Karen ^a   Buongiovanni, David ^a   Chen, Paul ^a  

^a Hydromer Inc   (United States)

Author keywords

Bioactivity biocompatibility; Coagulation; Heparin; Platelet adhesion; Thrombogenicity

Indexed keywords

BIOCHEMISTRY; BLOOD SUBSTITUTES; CHEMICALS; CLADDING (COATING); COATING TECHNIQUES; COMPUTER NETWORKS; CORROSION RESISTANT ALLOYS; INERT GAS WELDING; IRIDIUM; IRON; NETWORK PROTOCOLS; PAINTING; PLASMA (HUMAN); PLASTIC COATINGS; PLATELETS; POLYMERS; POLYSACCHARIDES; SPECTROSCOPIC ANALYSIS; STANDARDS; STEEL; STEEL CORROSION; STEEL METALLURGY; SURFACE PROPERTIES; SURFACES; WEIGHT CONTROL;

(1 1 0) SURFACE; ANTI THROMBOGENICITY; APPLIED (CO); COATED SURFACES; CYTOTOXIC; FLUORESCENT STAINING; HEPARIN (HEP); HUMAN ERYTHROCYTES; IMMUNOHISTOCHEMISTRY (IHC); MEDICAL IMPLANTS; PLATELET ADHESIONS; PLATELET-RICH-PLASMA (PRP); POLYMER COMPLEXES; POLYURETHANE (PU) FILMS; THROMBUS FORMATION; WHOLE BLOOD (WB);

STAINLESS STEEL;

HEPARIN; HYDROMER HEPARIN POLYMER COMPLEX; POLYMER; POLYURETHAN; STAINLESS STEEL;

ANTICOAGULATION; ARTICLE; BIOCOMPATIBILITY; ERYTHROCYTE; HEMOLYSIS; IMMUNOHISTOCHEMISTRY; IMPLANT; MATERIAL COATING; THROMBOCYTE ADHESION; THROMBOGENESIS; THROMBOGENICITY;

BIOCOMPATIBLE MATERIALS; BLOOD PLATELETS; CHITOSAN; FACTOR XA; HEPARIN; HUMANS; ISOCYANATES; MICROSCOPY, FLUORESCENCE; PLATELET ADHESIVENESS; POLYMERS; POLYURETHANES; POVIDONE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STAINLESS STEEL; THROMBOSIS;

EID: 45749134982     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.30998     Document Type: Article

References (23)

1. Marcum JA. The origin of the dispute over the discovery of heparin. J Hist Med Allied Sci 2000;55:37-66.
2. Muehrcke DD, McCarthy PM, Kottke-Marchant KK, Harasaki H, Pierre-Yared J, Borsh JA, Ogella DA, Cosgrove DM. Biocompatibility of heparin-coated extracorporeal bypass circuits: A randomized, masked clinical trial. J Thorac Cardiovasc Surg 1996;112:472-483.
3. Heyman PW, Cho CS, McRea JC, Olsen DB, Kim SW. Heparinized polyurethanes: In vitro and in vivo studies. J Biomed Mater Res 1985;19:419-436.
4. Kim HY, Han DK, Jeong YS, Ahn K-D. Surface modification of polyurethane for enhanced blood compatibility. Makromol Chem Macromol Symp 1990;3:319-326.
5. Cannan CR. Anti-thrombogenic therapy in cardiac stent patients. Curr Cardiol Rep 2001;3:78-84.
6. Vasudev SC, Chandy T, Sharma CP. Development of chitosan/polyethylene vinyl acetate co-matrix: Controlled release of aspirin-heparin for preventing cardiovascular thrombosis. Biomaterials 1997;18:375-381.
7. Sagnella S, Mai-Ngam K. Chitosan based surfactant polymers designed to improve blood compatibility on biomaterials. Colloids and Surfaces: Biointerfaces 2005;42:147-155.
8. Suggs LJ, West JL, Mikos AG. Platelet adhesion on a bioresorbable poly(propylene fumarate-co-ethylene glycol) copolymer. Biomaterials 1999;20:683-690.
9. Niimi Y, Ichinose F, Ishiguro Y, Terui K, Uezono S, Morita S, Yamane S. Platelet adhesion to heparin coated oxygenator fibers under in vitro static conditions: Impact of temperature. Anesth Analg 1999;89:573-579.
10. Helander IM, Nurmiaho-Lassila EL, Ahvenamen R, Rhoades J, Roller S. Chitosan disupts the barrier properties of the outer membrane of gram-negative bacteria. Int J Food Microbiol 2001;71:235-244.
11. Hwang JK, Kim HJ, Yoon SJ, Pyun YR. Bacteriacidal activity of chitosan on E. coli. In: Chen RH, Chen HC, editors Advances in Chitin Science. Taiwan: Rita Advertising; 1998. pp 340-344.
12. Fang SW, Li CF, Shih DYC. Antifungal activity of chitosan and its preservative effect on low-sugar candied Kumquat. J Food Prot 1994;56:136-140.
13. Tsai GJ, Su WH. Antibacterial activity of shrimp chitosan against Escherichia coli. J Food Prot 1999;62:239-243.
14. Liu XF, Guan YL, Yang DZ, Li Z, Yao KD. Antibacterial action of chitosan and carboxymethylated chitosan. J Appl Polym Sci 2000;79:1324-1335.
15. van der Graff F, Keus FJA, Vlooswijk RAA, Bouma BN. The contact activation mechanism in human plasma: Activation induced by dextran sulfate. Blood 1982;59:1225-1233.
16. Mille B, Watton J, Barrowcliffe TW, Mani J-C, Lane DA. Role of N- and C-terminal amino acids in antithrombin binding to pentasaccharide. J Biol Chem 1994;269:29435-29443.
17. Jin L, Abrahams JP, Skinner R, Petitou M, Pike RN, Carrell RW. The anticoagulant activation of antithrombin by heparin. Proc Natl Acad Sci USA 1997;94:14683-14688.
18. Capila I, Linhardt RJ. Heparin-protein interactions. Angew Chem Int Ed 2002;41:390-412.
19. Du YJ, Brash JL, McClung G, Berry LR, Klement P, Chan AKC. Protein adsorption on polyurethane catheters modified with a novel antithrombin-heparin covalent complex. J Biomed Mater Res 2007;1:216-225.
20. Sbarbati Del Guerra R, Lelli L, Tonelli C, Trombetta T, Cascone MG, Taveri M, Narducci P, Giusti P. In vitro biocompatibility of fluorinated polyurethanes. J Mater Sci 1994;5: 452-456.
21. Lin CW, Lin JC. Surface characterization and platelet compatibility evaluation of surface-sulfonated chitosan membrane. J Biomater Sci 2004;12:543-547.
22. Kocsis JF, Llanos G, Holmer E. Heparin-coated stents. J Long Term Eff Med Implants 2000;10:19-45.
23. Verheye S, Markou CP, Salame MY, Wan B, King SB III, Robinson KA, Chronos AF, Hanson SR. Reduced thrombus formation by hyaluronic acid coating of endovascular devices. Arterioscler Thromb Vasc Biol 2000;20:1168-1172.