Allogeneic hemopoietic stem cell transplantation for childhood acute lymphoblastic leukemia in second complete remission - Similar outcomes after matched related and unrelated donor transplant: A study of the Spanish working party for blood and marrow transplantation in children (Getmon)

Pediatric Hematology and Oncology

Volumn 25, Issue 4, 2008, Pages 245-259

  Munoz A ^a,l   Diaz Heredia, C ^b   Diaz, M A ^c   Badell, I ^d   Verdeguer, A ^e   Martinez, A ^f   Gomez, P ^g   Perez Hurtado, J M ^h   Bureo, E ⁱ   Fernandez Delgado, R ^j   Gonzalez Valentin, M E ^k   Maldonado, M S ^a  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

^b HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^c HOSPITAL INFANTIL UNIVERSITARIO NIÑO JESÚS   (Spain)

^d HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^e HOSPITAL UNIVERSITARIO LA FE   (Spain)

^f HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^g HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

^h HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

ⁱ HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

^j HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

^k HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

^l Servicio de Pediatría   (Spain)

more..

Author keywords

Acute lymphoblastic leukemia; Allogeneic; Related donor; Unrelated donor

Indexed keywords

ANTHRACYCLINE; ASPARAGINASE; BUSULFAN; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; ETOPOSIDE; METHOTREXATE; PREDNISONE; THYMOCYTE ANTIBODY; VINCRISTINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ARTICLE; CANCER REGRESSION; CANCER RELAPSE; CHILD; DONOR; FEMALE; FOLLOW UP; GRAFT REJECTION; GRAFT VERSUS HOST REACTION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFECTION; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIPLE ORGAN FAILURE; QUALITY OF LIFE;

ADOLESCENT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHILD; CHILD, PRESCHOOL; COMBINED MODALITY THERAPY; FEMALE; GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; INFANT; MALE; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; QUALITY OF LIFE; RECURRENCE; REMISSION INDUCTION; SURVIVAL RATE; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, HOMOLOGOUS; TREATMENT OUTCOME;

EID: 45749131779     PISSN: 08880018     EISSN: 15210669     Source Type: Journal    
DOI: 10.1080/08880010802016557     Document Type: Article

References (41)

1. Moghrabi A, Levy DE, Asselin BL, et al. Results of the Dana -Farber Cancer Institute ALL Consortium Protocol 95-01 for children with acute lymphoblastic leukaemia. Blood. 2007;109:896-904.
2. Goubin A, Auclerc FM, Auvrignon A, et al. Survival in France after childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma. Eur J Cancer. 2006;42:534-541.
3. Pui CH, Sandlund JT, Pei D, et al. Improved outcome for children with acute lymphoblastic leucemia: results of Total Therapy Study XIIIB at St. Jude Childrens Research Hospital. Blood. 2004;104:2690-2696.
4. Badell I, Cubells J. Therapeutic results in childhood acute lymphoblastic leukaemia with the SHOP protocols of the Spanish Society of Pediatric Hematology and the Spanish Society of Pediatric Oncology, 1989-2005. Rev Esp Pediatr. 2005;61:273-281.
5. Gaynon PS. Childhood acute lymphoblastic leukaemia and relapse. Br J Haematol. 2005;131:579-589.
6. Hahn T, Wall D, Camitta B, et al. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute lymphoblastic leukaemia in children: an evidence-based review. Biol Blood Marrow Transplant. 2005;11:823-861.
7. Badell I, Muñoz A, Ortega JJ, et al. Long-term outcome of allogeneic or autologous haemopoietic cell transplantation for acute lymphoblastic leukaemia in second remission in children. GETMON experience 1983-1998. Bone Marrow Transplant. 2005;35:895-901.
8. Veys P, Amrolla P, Rao K. The role of haploidentical stem cell transplantation in the management of children with haematological disorders. Br J Haematol. 2003;123:193-206.
9. Flomenberg N, Baxter-Lowe LA, Confer D, et al. Impact of HLA class I and HLA class II high resolution matching on outcomes of unrelated bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome. Blood. 2004;104:1923-1930.
10. Oakhill A, Pamphilon DH, Potter MN, et al. Unrelated donor bone marrow transplantation for children with relapsed acute lymphoblastic leukaemia in second complete remission. Br J Haematol. 1996;94:574-578.
11. Green A, Clarke E, Hunt L, et al. Children with acute lymphoblastic leukaemia whom receive T-cell depleted HLA mismatched marrow allografts from unrelated donors have an increased incidence of primary graft failure but a similar overall trasplant outcome. Blood. 1999;94:2236-2246.
12. Bunin N, Carston M, Wall D, et al. Unrelated marrow transplantation for children with acute lymphoblastic leukaemia in second remission. Blood. 2002;99:3151-3157.
13. Woolfrey AE, Anasseti C, Storer B, et al. Factors associated with outcome after unrelated marrow transplantation for treatment of acute lymphoblastic leukaemia in children. Blood. 2002:2002-2008.
14. Dini G, Valchessi MG, Micalizzi C, et al. Impact of marrow unrelated donor search duration on outcome of children with acute lymphoblastic leukemia in second remission. Bone Marrow Transplant. 2003;32:325-331.
15. Lang P, Handgretinger R, Niethammer D, et al. Transplantation of highly purified CD34+ progenitor cells from unrelated donors in pediatric leukaemia. Blood. 2003;101:1630-1633.
16. Afify Z, Hunt L, Green A, Guttridge M, Cornish J, Oakhill A. Factors affecting the outcome of stem cell transplantation from unrelated donors for childhood acute lymphoblastic leukaemia in third remission. Bone Marrow Transplant. 2005;35:1041-1047.
17. Hongens S, Krance RA, Bowman LC, et al. Outcomes of transplantation with matched-sibling and unrelated-donor bone marrow in children with leukemia. Lancet. 1997;350:767-771.
18. Lausen BF, Heiman C, Vindelov L, Jacobsen N. Outcome of acute lymphoblastic leukaemia in Danish children after allogeneic bone marrow transplantation: superior survival following transplantation with matched unrelated donor grafts. Bone Marrow Trasplant. 1998;22:325-330.
19. Al-Kasim FA, Thornley I, Rolland M, et al. Single-centre experience with allogeneic bone marrow transplantation for acute lymphoblastic leukaemia in childhood: similar survival after matched-related and matched-unrelated donor transplant. Br J Haematol. 2002;116:483-490.
20. Ortega JJ, Ribera JM, Oriol A, et al. Early and delayed consolidation chemotherapy significantly improves the out of children with intermediate risk outcome of children with intermediate risk acute lymphoblastic leukaemia. Final Results of the prospective randomized PETHEMA ALL TRIAL. Haematologica. 2001;86:586-595.
21. Cox DR. Regression models and life tables. J R Stat Soc B. 1972;34:187-220.
22. Saarinen-Pihkala UM, Gustafsson G, Rindgen O, et al. No disadvantage in outcome of using matched unrelated donors as compared with matched sibling donors for bone marrow transplantation in children with acute lymphoblastic leukemia in second remission. J Clin Oncol. 2001;19:3406-3414.
23. Sedlácek P, Formánkova R, Keslová P, et al. Low mortality of children undergoing hematopoietic stem cell transplantation from 7 to 8/10 human leukocyte antigen allele-matched unrelated donors with the use of antithymocyte globulin. Bone Marrow Transplant. 2006;38:745-750.
24. Arcese W, Guglielmi C, Iori AP, Screnci M, Carmini D, Testi AM. Umbilical cord blood transplants from unrelated HLA-mismatched donors in children with high-risk leukaemia. Bone Marrow Transplant. 1999;23:549-554.
25. Boulad F, Steinherz P, Reyes B, Heller G, Gillio AP, Small TN, et al. Allogeneic bone marrow transplantation versus chemotherapy for the treatment of childhood acute lymphoblastic leukaemia in second complete remission: a single-institution study. J Clin Oncol. 1999;17:197-207.
26. Gaynon PS, Harris RE, Altman AJ, et al. Bone marrow transplantation versus prolonged intensive chemotherapy for children with acute lymphoblastic leukaemia and an initial bone marrow relapse within12 months of the completion of primary therapy: Childrens Oncology Group study CCG-1941. J Clin Oncol. 2006;24:3150-3156.
27. Zecca M, Pession A, Messina C, et al. Total body irradiation, thiotepa and cyclophosphamide as a conditioning regimen for children with acute lymphoblastic leukemia in first or second remission undergoing bone marrow transplantation with HLA- identical siblings. J Clin Oncol. 1999;17:1839-1846.
28. Borgmann A, Baumgarten E, Schmidt H, et al Allogeneic bone marrow transplantation for a subset of children with acute lymphoblastic leukaemia in third remission: a conceivable alternative? Bone Marrow Transplant. 1997;20:939-944.
29. Gustafsson Jerberg A, Ringden O, Wianirski J. Graft-versus- leukaemia effect in children: chronic GvHD has a significant impact on relapse and survival. Bone Marrow Transplant. 2003;31:175-181.
30. Jamieson CHM, Amylon MD, Wong RM, Blume KG. Allogeneic hemopoietic cell transplantation for patients with high-risk acute lymphoblastic leukaemia in first or second remission using fractionated total-body irradiation and high-dose etoposide: a 15-years experience. Exp Hematol. 2003;31:981-986.
31. Balduzzi A, Gooley T, Anasseti C, et al. Unrelated donor marrow transplantation in children. Blood. 1995;86:3247-3256.
32. Davies SM, Wagner JE, Shu XO, et al. Unrelated donor transplantation for children with acute leukaemia. J Clin Oncol. 1997;15:557-565.
33. Borgmann A, Baldy C, von Stalkelberger A, et al. Unrelated donor stem-cell transplantation compared with chemotherapy for children with acute lymphoblastic leukaemia in second d remission: a matched pair analysis. Blood. 2003;17:635-650.
34. Benito AI, Gonzalez-Vicent M, Garcia F, et al. Allogeneic peripheral blood stem cell transplantation from HLA-identical sibling donors in children with hematologic diseases: a single center pilot study. Bone Marrow Transplant. 2001;28:537-543.
35. Meisel R, Enczmann J, Balzer S, et al. Similar survival following HLA-identical sibling transplantation for standard indication in children with haematological malignancies: a single center comparison of mobilized peripheral blood stem cell with bone marrow transplantation. Klin Padiatr. 2005;217:135-141.
36. Vicent MG, Madero L, Ortega JJ, et al. Matched-pair analysis comparing allogeneic PBPCT and BMT from HLA-identical relatives in childhood acute lymphoblastic leukaemia. Bone Marrow Transplant. 2002;30:9-13.
37. Eapen M, Horowitz MM, Klein JP, et al.Highermortality after allogeneic peripheral blood stem cell transplantation compared with bone marrow in children and adolescents: The Histocompatibility and Alternate Stem Cell Source Working Party Committee of the International Bone Marrow Transplant Registry. J Clin Oncol. 2004;22:4872-4880.
38. Mullighan CG, Bardy PG. New directions in the genomics of allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2007;13:127-144.
39. Baron C, Somogyi R, Greller RD, et al. Predictor of graft-versus-host disease in humans by donor gene-expression profiling. PLoS Med. 2007;4:e23.
40. Perez-Simon JA, Sanchez-Abarca I, Diez-Campelo M, Caballero D, San Miguel J. Chronic graft-versus-host disease: pathogenesis and clinical management. Drugs. 2006;66:1041-1057.
41. Sramkova L, Muzikova K, Froncova E, et al. Detectable minimal residual disease before allogeneic hematopoietic stem cell transplantation predicts extremely poor prognosis in children with acute lymphoblastic leukaemia. Pediatr Blood Cancer. 2007:93-100.