Transcriptional response of dermal fibroblasts in direct current electric fields

Bioelectromagnetics

Volumn 29, Issue 5, 2008, Pages 394-405

  Jennings, Jessica ^a,c   Chen, Dongquan ^b   Feldman, Dale ^a  

^a and Radiation Oncology   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c NONE   (United States)

Author keywords

Dermal; Gene expression; Injury current; Microarray; Wound healing

Indexed keywords

BIOSYNTHESIS; CELL CULTURE; CELL DEATH; FIBROBLASTS; GENE EXPRESSION; MICROARRAYS; PROTEINS; REPAIR;

'CURRENT; CELLULAR SIGNALLING; DERMAL; DERMAL FIBROBLASTS; EXPOSED TO; GENES EXPRESSION; INJURY CURRENT; TRANSCRIPTIONAL RESPONSE; WOUND HEALING; WOUND REPAIR;

ELECTRIC FIELDS;

GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

APOPTOSIS; ARTICLE; CELL GROWTH; CONTROLLED STUDY; DIRECT CURRENT; ELECTRIC FIELD; FIBROBLAST; FN1 GENE; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; JUMONJI DOMAIN CONTAINING 1C GENE; KRUPPEL LIKE FACTOR 6 GENE; MICROARRAY ANALYSIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RGS2 GENE; WOUND HEALING;

EID: 45749118811     PISSN: 01978462     EISSN: 1521186X     Source Type: Journal    
DOI: 10.1002/bem.20408     Document Type: Article

References (62)

1. Alvarez OM, Mertz PM, Smerbeck RV, Eaglstein WH. 1983. The healing of superficial skin wounds is stimulated by external electrical current. J Invest Dermatol 81(2):144-148.
2. Assimacopoulos D. 1968. Low intensity negative electric current in the treatment of ulcers of the leg due to chronic venous insufficiency. Preliminary report of three cases. Am J Surg 115(5):683-687.
3. Barker A, Jaffe L, Vanable J. 1982. The glabrous epidermis of cavies contains a powerful battery. Am J Physiol 242(3):R358-R366.
4. Bassett C, Herrmann I. 1968. The effect of electrostatic fields on macromolecular synthesis by fibroblasts in vitro. J Cell Biol 39:9.
5. Bayat M, Asgari-Moghadam Z, Maroufi M, Rezaie FS, Bayat M, Rakhshan M. 2006. Experimental wound healing using microamperage electrical stimulation in rabbits. J Rehabil Res Dev 43(2):219-226.
6. Binhi V, Goldman R. 2000. Ion-protein dissociation predicts 'windows' in electric field-induced wound-cell proliferation. Biochim Biophys Acta 1474:147-156.
7. Borgens RB, Vanable JW, Jr., Jaffe LF. 1977. Bioelectricity and regeneration: Large currents leave the stumps of regenerating newt limbs. Proc Natl Acad Sci USA 74(10):4528-4532.
8. Bourguignon GJ, Bourguignon LY. 1987. Electric stimulation of protein and DNA synthesis in human fibroblasts. FASEB J 1(5):398-402.
9. Bourguignon GJ, Jy W, Bourguignon LY. 1989. Electric stimulation of human fibroblasts causes an increase in Ca2+ influx and the exposure of additional insulin receptors. J Cell Physiol 140(2):379-385.
10. Bourguignon LY, Singleton PA, Zhu H, Zhou B. 2002. Hyaluronan promotes signaling interaction between CD44 and the transforming growth factor beta receptor I in metastatic breast tumor cells. J Biol Chem 277(42):39703-39712.
11. Chao PH, Lu HH, Hung CT, Nicoll SB, Bulinski JC. 2007. Effects of applied DC electric field on ligament fibroblast migration and wound healing. Connect Tissue Res 48(4):188-197.
12. Cheng K, Goldman RJ. 1998. Electric fields and proliferation in a dermal wound model: Cell cycle kinetics. Bioelectromagnetics 19(2):68-74.
13. Clark RAF. 1995. Wound repair: Overview and general considerations. In: Clark RAF, editor. The molecular and cellular biology of wound repair, 2nd edition. New York: Plenum Press. pp 3-50.
14. Clark RA, Henson PM. 1988. The molecular and cellular biology of wound repair. New York: Plenum Press.
15. Druey KM. 2001. Bridging with GAPs: receptor communication through RGS proteins. Sci STKE 2001(104):RE14.
16. Erickson CA, Nuccitelli R. 1984. Embryonic fibroblast motility and orientation can be influenced by physiological electric fields. J Cell Biol 98(1):296-307.
17. Falanga V, Bourguignon G, Bourguignon L. 1987. Electrical stimulation increases the expression of fibroblast receptors for transforming growth factor-beta. J Invest Dermatol 88:488-492.
18. Fang KS, Ionides E, Oster G, Nuccitelli R, Isseroff RR. 1999. Epidermal growth factor receptor relocalization and kinase activity are necessary for directional migration of keratinocytes in DC electric fields. J Cell Sci 112(Pt 12):1967-1978.
19. Fava RA, McClure DB. 1987. Fibronectin-associated transforming growth factor. J Cell Physiol 131(2):184-189.
20. Finkelstein E, Chang W, Chao PH, Gruber D, Minden A, Hung CT, Bulinski JC. 2004. Roles of microtubules, cell polarity and adhesion in electric-field-mediated motility of 3T3 fibroblasts. J Cell Sci 117(Pt 8):1533-1545.
21. Foulds IS, Barker AT. 1983. Human skin battery potentials and their possible role in wound healing. Br J Dermatol 109(5):515-522.
22. Freissmuth M, Casey PJ, Gilman AG. 1989. G proteins control diverse pathways of transmembrane signaling. FASEB J 3(10):2125-2131.
23. Gabbiani G, Ryan G, Majno G. 1971. Presence of modified fibroblasts in granulation tissue and possible role of wound contraction. Experientia 27:549.
24. Gaidarov I, Smith ME, Domin J, Keen JH. 2001. The class II phosphoinositide 3-kinase C2alpha is activated by clathrin and regulates clathrin-mediated membrane trafficking. Mol Cell 7(2):443-449.
25. Gardner SE, Frantz RA, Schmidt FL. 1999. Effect of electrical stimulation on chronic wound healing: A meta-analysis. Wound Repair Regen 7(6):495-503.
26. Hunt T. 1980. Wound healing and wound infection: Theory and surgical practice. New York: Appleton-Century-Crofts.
27. Ignotz RA, Massague J. 1986. Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem 261(9):4337-4345.
28. Irizarry RA, Wu Z, Jaffee HA. 2006. Comparison of Affymetrix GeneChip expression measures. Bioinformatics 22(7):789-794.
29. Jaffe LF, Vanable JW, Jr. 1984. Electric fields and wound healing. Clin Dermatol 2(3):34-44.
30. Jonsson G, Paulie S, Grandien A. 2003. High level of cFLIP correlates with resistance to death receptor-induced apoptosis in bladder carcinoma cells. Anticancer Res 23(2B): 1213-1218.
31. Jung J, Mysliwiec MR, Lee Y. 2005. Roles of JUMONJI in mouse embryonic development. Dev Dyn 232(1):21-32.
32. Kim Y, Ratziu V, Choi S, Lalazar A, Theiss G, Dang Z, Kim S, Friedman S. 1998. Transcriptional activation of transforming growth factor beta1 and its receptors by the Kruppel-like factor Zf9/core promoter-binding protein and Sp1. Potential mechanisms for autocrine fibrinogenesis in response to injury. J Biol Chem 273:33750-33758.
33. Kim JW, Cho HS, Kim JH, Hur SY, Kim TE, Lee JM, Kim IK, Namkoong SE. 2000. AAC-11 overexpression induces invasion and protects cervical cancer cells from apoptosis. Lab Invest 80(4):587-594.
34. Kloth LC. 2005. Electrical stimulation for wound healing: A review of evidence from in vitro studies, animal experiments, and clinical trials. Int J Low Extrem Wounds 4(1):23-44.
35. Méthot S, Moulin V, Rancourt D, Bourdages D, Plante M, Auger F, Germain L. 2001. Morphological changes of human skin cells exposed to a DC electric field in vitro using a new exposure system. Can J Chem Eng 79:668-677.
36. Morris EJ, Michaud WA, Ji JY, Moon NS, Rocco JW, Dyson NJ. 2006. Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo. PLoS Genet 2(11):e196.
37. Nelson RM, Hayes KW, Currier DP. 1999. Clinical electrotherapy. Stamford, Conn.: Appleton & Lange. xii, 578 p.
38. Nuccitelli R. 2003. A role for endogenous electric fields in wound healing. Curr Top Dev Biol 58:1-26.
39. Okamoto M, Ono M, Uchiumi T, Ueno H, Kohno K, Sugimachi K, Kuwano M. 2002. Up-regulation of thrombospondin-1 gene by epidermal growth factor and transforming growth factor beta in human cancer cells - Transcriptional activation and messenger RNA stabilization. Biochim Biophys Acta 1574(1):24-34.
40. Parent CA, Devreotes PN. 1999. A cell's sense of direction. Science 284(5415):765-770.
41. Postlethwaite AE, Keski-Oja J, Balian G, Kang AH. 1981. Induction of fibroblast chemotaxis by fibronectin. Localization of the chemotactic region to a 140,000-molecular weight nongelatin-binding fragment. J Exp Med 153(2):494-499.
42. Ratziu V, Lalazar A, Wong L, Dang Q, Collins C, Shaulian E, Jensen S, Friedman SL. 1998. Zf9, a Kruppel-like transcription factor up-regulated in vivo during early hepatic fibrosis. Proc Natl Acad Sci USA 95(16):9500-9505.
43. Reger SI, Hyodo A, Negami S, Kambic HE, Sahgal V. 1999. Experimental wound healing with electrical stimulation. Artif Organs 23(5):460-462.
44. Reid B, Song B, McCaig CD, Zhao M. 2005. Wound healing in rat cornea: The role of electric currents. FASEB J 19(3):379-386.
45. Schlapbach R, Spanaus KS, Malipiero U, Lens S, Tasinato A, Tschopp J, Fontana A. 2000. TGF-beta induces the expression of the FLICE-inhibitory protein and inhibits Fas-mediated apoptosis of microglia. Eur J Immunol 30(12):3680-3688.
46. Sillman AL, Quang DM, Farboud B, Fang KS, Nuccitelli R, Isseroff RR. 2003. Human dermal fibroblasts do not exhibit directional migration on collagen I in direct-current electric fields of physiological strength. Exp Dermatol 12(4):396-402.
47. Sporn M, Roberts A. 1986. Peptide growth factors and inflammation, tissue repair, and cancer. J Clin Invest 78:329-332.
48. Stelnicki EJ, Longaker MT, Holmes D, Vanderwall K, Harrison MR, Largman C, Hoffman WY. 1998. Bone morphogenetic protein-2 induces scar formation and skin maturation in the second trimester fetus. Plast Reconstr Surg 101(1): 12-19.
49. Sun S, Wise J, Cho M. 2004. Human fibroblast migration in three-dimensional collagen gel in response to noninvasive electrical stimulus. I. Characterization of induced three-dimensional cell movement. Tissue Eng 10(9-10):1548-1557.
50. Takeuchi T, Watanabe Y, Takano-Shimizu T, Kondo S. 2006. Roles of jumonji and jumonji family genes in chromatin regulation and development. Dev Dyn 235(9):2449-2459.
51. Tewari M, Yu M, Ross B, Dean C, Giordano A, Rubin R. 1997. AAC-11, a novel cDNA that inhibits apoptosis after growth factor withdrawal. Cancer Res 57(18):4063-4069.
52. Toyoda M, Kojima M, Takeuchi T. 2000. Jumonji is a nuclear protein that participates in the negative regulation of cell growth. Biochem Biophys Res Commun 274(2):332-336.
53. Tsirogianni AK, Moutsopoulos NM, Moutsopoulos HM. 2006. Wound healing: Immunological aspects. Injury 37 (Suppl 1): S5-S12.
54. Wajant H, Haas E, Schwenzer R, Muhlenbeck F, Kreuz S, Schubert G, Grell M, Smith C, Scheurich P. 2000. Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD). J Biol Chem 275(32):24357-24366.
55. Wang E, Yin Y, Zhao M, Forrester JV, McCaig CD. 2003. Physiological electric fields control the G1/S phase cell cycle checkpoint to inhibit endothelial cell proliferation. FASEB J 17(3):458-460.
56. Werner S, Krieg T, Smola H. 2007. Keratinocyte-fibroblast interactions in wound healing. J Invest Dermatol 127(5): 998-1008.
57. Wettschureck N, Offermanns S. 2005. Mammalian G proteins and their cell type specific functions. Physiol Rev 85(4):1159-1204.
58. Yanagida Y, Mizuno A, Motegi T, Kobatake E, Aizawa M. 2000. Electrically stimulated induction of hsp70 gene expression in mouse astroglia and fibroblast cells. J Biotechnol 79(1): 53-61.
59. Zhao M, Dick A, Forrester JV, McCaig CD. 1999. Electric field-directed cell motility involves up-regulated expression and asymmetric redistribution of the epidermal growth factor receptors and is enhanced by fibronectin and laminin. Mol Biol Cell 10(4):1259-1276.
60. Zhao M, Jin T, McCaig CD, Forrester JV, Devreotes PN. 2002. Genetic analysis of the role of G protein-coupled receptor signaling in electrotaxis. J Cell Biol 157(6):921-927.
61. Zhao M, Song B, Pu J, Wada T, Reid B, Tai G, Wang F, Guo A, Walczysko P, Gu Y, Sasaki T, Suzuki A, Forrester JV, Bourne HR, Devreotes PN, McCaig CD, Penninger JM. 2006. Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-gamma and PTEN. Nature 442(7101):457-460.
62. Zhao Y, Gaidarov I, Keen JH. 2007. Phosphoinositide 3-kinase C2alpha links clathrin to microtubule-dependent movement. J Biol Chem 282(2):1249-1256.