An experimentally constrained computational model of NMDA oscillations in lamprey CPG neurons

Journal of Computational Neuroscience

Volumn 25, Issue 1, 2008, Pages 108-121

  Huss, Mikael ^a,b   Wang, Di ^b   Trané, Camilla ^a   Wikström, Martin ^b   Hellgren Kotaleski, Jeanette ^a,b  

^a ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

CPG; Frequency dependence; Locomotion; NMDA; Single neuron oscillations

Indexed keywords

COMPUTATION THEORY; COMPUTATIONAL METHODS; NEURAL NETWORKS; SENSITIVITY ANALYSIS;

COMPUTATIONAL MODELLING; CPG; D-ASPARTATE; EXPERIMENTAL EVIDENCE; FREQUENCIES DEPENDENCE; LOCOMOTION; N-METHYL-D-ASPARTATE; NEURAL-NETWORKS; SINGLE NEURON; SINGLE-NEURON OSCILLATION;

NEURONS;

N METHYL DEXTRO ASPARTIC ACID RECEPTOR; TETRODOTOXIN; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL;

ARTICLE; CHANNEL GATING; COMPUTER ANALYSIS; COMPUTER MODEL; CONCEPTUAL FRAMEWORK; LAMPREY; LOCOMOTION; MEMBRANE POTENTIAL; NERVE CELL NETWORK; NONHUMAN; OSCILLATION; PATTERN GENERATOR; PREDICTION; PRIORITY JOURNAL; REPRODUCIBILITY; SENSITIVITY ANALYSIS; SIMULATION;

EID: 45649085311     PISSN: 09295313     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10827-007-0067-1     Document Type: Article

References (28)

1. Ascher, P., & Nowak, L. (1988). The role of divalent cations in the N-methyl-d-aspartate responses of mouse central neurones in culture. Journal of Physiology London, 399, 247-266.
2. Brodin, L., Tråvén, H. G., Lansner, A., Wallén, P., Ekeberg, Ö., & Grillner, S. (1991). Computer simulations of N-methyl-d-aspartate receptor-induced membrane properties in a neuron model. Journal of Neurophysiology, 66, 473-484.
3. Brodin, L., Grillner, S., & Rovainen, C. M. (1985). N-methyl-d-aspartate (NMDA), kainate and quisqualate receptors and the generation of fictive locomotion in the lamprey spinal cord. Brain Research, 325, 302-306.
4. Büschges, A., Wikström, M. A., Grillner, S., & El Manira, A. (2000). Roles of high-voltage activated calcium channel subtypes in a vertebrate spinal locomotor network. Journal of Neurophysiology, 85, 2758-2766.
5. El Manira, A., & Bussières, N. (1997). Calcium channel subtypes in lamprey sensory and motor neurons. Journal of Neurophysiology, 78, 1334-1340.
6. El Manira, A., Tegnér, J., & Grillner, S. (1994). Calcium-dependent potassium channels play a critical role for burst termination in the locomotor network in lamprey. Journal of Neurophysiology, 72, 1852-1861.
7. Ermentrout, B. (2002). Simulating, analyzing and animating dynamical systems: A guide to XPPAUT for researchers and students. Philadelphia: SIAM.
8. Grillner, S., & Wallén, P. (1985). The ionic mechanisms underlying N-methyl-d-aspartate receptor-induced, tetrodotoxin-resistant membrane potential oscillations in lamprey neurons active during locomotion. Neuroscience Letters, 60, 289-294.
9. Guertin, P. A., & Hounsgaard, J. (1998). Chemical and electrical stimulation induce rhythmic motor activity in an in vitro preparation of the spinal cord from adult turtles. Neuroscience Letters, 245, 5-8.
10. Guertin, P. A., & Hounsgaard, J. (2006). Conditional intrinsic voltage oscillations in mature vertebrate neurons undergo specific changes in culture. Journal of Neurophysiology, 95, 2024-2027.
11. Heinrich, R., & Rapoport, T. A. (1974). A linear steady-state treatment of enzymatic chains. Critique of the crossover theorem and a general procedure to identify interaction sites with an effector. European Journal of Biochemistry, 42, 97-105.
12. Hess, D., Nanou, E., & El Manira, A. (2007). Characterization of Na+ -activated K+ currents in larval lamprey spinal cord neurons. Journal of Neurophysiology, 97, 3484-3493.
13. Huss, M., Lansner, A., Wallén, P., El Manira, A., Grillner, S., & Hellgren Kotaleski, J. (2007). Roles of ionic currents in lamprey CPG neurons: A modeling study. Journal of Neurophysiology, 97, 2696-2711.
14. - injections. Journal of Comparative Physiology, 147, 189-194.
15. Kozlov, A., Hellgren Kotaleski, J., Aurell, E., Grillner, S., & Lansner, A. (2001) Modeling of substace P and 5-HT induced synaptic plasticity in the lamprey spinal CPG: Consequences for network pattern generation. Journal of Computational Neuroscience, 11, 183-200.
16. Ingalls, B. P. (2004). Autonomously oscillating biochemical systems: Parametric sensitivity of extrema and period. IEE Systems Biology, 1, 62-70.
17. MacLean, J. N., Schmidt, B. J., Hochman, S. (1997). NMDA receptor activation triggers voltage oscillations, plateau potentials and bursting in neonatal rat lumbar motoneurons in vitro. European Journal of Neuroscience, 9, 2702-2711.
18. Moore, L., & Buchanan, J. (1993). The effects of neurotransmitters on the integrative properties of spinal neurons in the lamprey. Journal of Experimental Biology, 175, 89-114.
19. Nowak, L., Bregestovski, P., Ascher, P., Herbet, P., & Prochiantz, A. (1984). Magnesium gates glutamate-activated channels in mouse central neurones. Nature, 307, 462-465.
20. Russell, D. F., & Wallén, P. (1983). On the control of myotomal motoneurones during "fictive swimming" in the lamprey spinal cord in vitro. Acta Physiologica Scandinavica, 117, 161-170.
21. Schmidt, H., & Jirstrand, M. (2006). Systems biology toolbox for MATLAB: A computational platform for research in systems biology. Bioinformatics, 22, 514-515.
22. Schmidt, B. J., Hochman, S., & MacLean, J. N. (1998). NMDA receptor-mediated oscillatory properties: Potential role in rhythm generation in the mammalian spinal cord. Annals of the New York Academy of Sciences, 860, 189-202.
23. Sillar, K. T., & Simmers, A. J. (1994). 5-HT induces NMDA receptor-mediated intrinsic oscillations in embryonic amphibian spinal neurons. Proceedings of the Royal Society of London Series B Biological Sciences, 255, 139-145.
24. Tegnér, J., & Grillner S. (1999). Interactive effects of the GABABergic modulation of calcium channels and calcium-dependent potassium channels in lamprey. Journal of Neurophysiology, 81, 1318-1329.
25. Tegnér, J., Lansner, A., & Grillner, S. (1998). Modulation of burst frequency by calcium-dependent potassium channels in the lamprey locomotor system: Dependence of the activity level. Journal of Computational Neuroscience, 5, 121-140.
26. Wallén, P., & Grillner, S. (1987). N-methyl-D-aspartate receptorinduced, inherent oscillatory activity in neurons active during fictive locomotion in the lamprey. Journal of Neuroscience, 7, 2745-2755.
27. Wallén, P., & Williams, T. (1984). Fictive locomotion in the lamprey spinal cord in vitro compared with swimming in the intact and spinal animal. Journal of Physiology, 347, 225-239.
28. Wikström, M. A., & El Manira, A. (1998). Calcium influx through N- and P/Q-type channels activate apamin-sensitive calcium-dependent potassium channels generating the late afterhyperpolarization in lamprey spinal neurons. European Journal of Neuroscience, 10, 1528-1532.