Review of bioactive compounds from fungi in the South China Sea

Botanica Marina

Volumn 51, Issue 3, 2008, Pages 179-190

  Pan, Jia Hui ^a   Jones, E B Gareth ^b   She, Zhi Gang ^a   Pang, Ji Yan ^a   Lin, Yong Cheng ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY   (Thailand)

Author keywords

Bioactive metabolites; Fungal endophytes; Obligate and marine derived fungi; South China Sea

Indexed keywords

BIOACTIVITY; FUNGUS; MARINE ENVIRONMENT; METABOLISM;

PACIFIC OCEAN; SOUTH CHINA SEA;

FUNGI;

EID: 45549103606     PISSN: 00068055     EISSN: 14374323     Source Type: Journal    
DOI: 10.1515/BOT.2008.030     Document Type: Conference Paper

References (110)

1. Abbanat, D., M. Leighton, W. Maise, E.B.G. Jones, C. Pierce and M. Greenstein. 1998. Cell wall active antifungal compounds produced by the marine fungus Hypoxylon oceanicum LL-15G256. 1. Taxonomy and fermentation. J. Antibiot. 51: 296-302.
2. Abdel-Wahab, M.A. 2000. Biodiversity of fungi in subtropical mangroves. PhD thesis. South Valley University, Egypt.
3. Abdel-Wahab, M.A. and H.M. El-Sharouny. 2002. Ecology of subtropical mangrove fungi with emphasis on Kandelia candel mycota. In: (K.D. Hyde, ed.) Fungi in marine environments. Fungal Diversity Research Series, Vol. 7. Fungal Diversity Press, Chiang Mai. pp. 247-265.
4. Abdel-Wahab, M.A., E.B.G. Jones and L.L.P. Vrijmoed. 1999. Endophytic fungi associated with Kandelia candel mangrove tree in Hong Kong. In: Abstracts of the 7th International Marine and Freshwater Mycology Symposium, City University of Hong Kong, Hong Kong. p. 52.
5. Abrell, L.M., B. Borgeson and P. Crews. 1996. Chloro polyketides from the cultured fungus (Aspergillus) separated from a marine sponge. Tetrahedron Lett. 37: 1331-1334.
6. Alam, M., E.B.G. Jones, M. Hossain and H.D. Bilayet. 1996. Isolation and structure of isoculmorin from the marine fungus Kallichroma tethys. J. Nat. Prod. 59: 454-456.
7. Anthony, G., J. Avent, R. Hanson and A. Truneh. 1992a. Two pyrones from Gliocladium vermoesenii. Phytochemistry 31: 1065-1066.
8. Anthony, G., J. Avent and R. Hanson. 1992b. The biosynthesis of nectriapyrone and vermopyrone. Phytochemistry 31: 3447-3449.
9. Arnone, A., R. Cardillo, G. Nasini and O.V. Depava. 1993. Secondary mold metabolites. Part 40. Two cinnamic allenic ethers from the fungus Clitocybe eucalyptorum. Phytochemistry 32: 1279-1281.
10. Ayer, W.A., I.V. Altena and L.M. Browne. 1990. Three piperazinediones and a drimane diterpenoid from Penicillium brevicompactum. Phytochemistry 29: 1661-1665.
11. Balasubramanian, K. and K. Rajagopalan. 1988. Studies of indigenous medicinal plants. Part 1. Novel xanthones from Garcinia mangostana, structures of BR-xanthone-A and BR-xanthone-B. Phytochemistry 27: 1552-1554.
12. Barry, R.D. 1964. Isocoumarins. Developments since 1950. Chem. Rev. 64: 229-260.
13. Bills, G.F. and J.D. Polishook. 1992. Recovery of endophytic fungi from Chamaecyparis thyoides. Sydowia 44: 1-12.
14. Bugni, T.S., D. Abbanata, V.S. Bernan, W.M. Maiese, M. Greenstein, R.M. Van Wagoner and C.M. Ireland. 2000. Yanuthones: novel metabolites from a marine isolate of Aspergillus niger. J. Org. Chem. 65: 7195-7200.
15. Chen, G.Y., Y.C. Lin, L. Wen, L.L.P. Vrijmoed and E.B.G. Jones. 2003. Two new metabolites of a marine endophytic fungus No.1893 from an estuarine mangrove on the South China Sea coast. Tetrahedron 59: 4907-4909.
16. Chen, G.Y., Y.C. Lin, L.L.P. Vrijmoed and W.F. Fong. 2006a. A new isochroman from the marine endophytic fungus #1893. Chem. Nat. Compd. 42: 138-141.
17. Chen, H.Y., Y.C. Lin, G.Y. Chen, G.P. Hu, L. Wang and L.L.P. Vrijmoed. 2006b. Catalytic transfer hydrogenation of mycoepoxydiene. Chem. Nat. Compd. 42: 407-409.
18. Chinworrungsee, M., P. Kittakoop, M. Isaka, A. Rungrod, M. Tanticharorn and Y. Thebtaranonth. 2001. Antimalarial halorosellinic acid from the marine fungus Halorosellinia oceanica. Bioorg. Med. Chem. Letters 11: 1965-1969.
19. Dong, Y.S., Z.H. Zheng, Q. Zhang, H. Zhang, X.Q. Lu, W. Shu, Y.Q. Dan, Y. Ma, Y.M. Mu and B.K. He. 2002. N98-1021A, a selective acetylcholinesterase inhibitors derived from microorganisms. Chin. J. Antibiot. 27: 260-263.
20. Eaton, M.A. and W.D. Hutchinson. 1971. Isocoumarins from Streptomyces mobaraensis. Tetrahedron Lett. 18: 1337-1340.
21. Eliane, G., M.S. Courtney, R.J. Paul, W. Fenical, E. Lobkovsky and J. Clardy. 2003. Trichodermamides A and B, cytotoxic modified dipeptides from the marine-derived fungus Trichoderma virens. J. Nat. Prod. 66: 423-426.
22. Faulkner, D. 1999. Marine natural products. Nat. Prod. Rep. 16: 155-198.
23. Fenical, W. 1993. Chemical studies of marine bacteria: developing a new resource. Chem. Rev. 93: 1673-1683.
24. Guerriero, A., M. D'Ambrosio, V. Cuomo, F. Vanzanella and F. Pietra. 1988. Novel trinor-ermophilanes (dedryphiellin B, C, D), ermophilanes (dendyphiellin E, F G) and branched C9-carboxylic acids (dendryphiellic acid A, B) from the marine deuteromycete Dendryphiella salina (Sutherland) Pugh et Nicot. Helv. Chim. Acta 72: 438-446.
25. 13C NMR signal assignments of Paecilin A and B, two new chromone derivatives from mangrove endophytic fungus Paecilomyces sp. (tree 1-7). Magn. Reson. Chem. 45: 777-780.
26. 13C NMR assignments for two oxaphenalenones bacillosporin C and D from the mangrove endophytic fungus SBE-14. Magn. Reson. Chem. 45: 439-441.
27. Hiroyuki, Y., K. Hirai, S. Yamamoto, K.-i. Takao and K.-i. Tadano. 2006. Total synthesis of (q)-1893B aimed at establishing its stereochemistry. Heterocycles 67: 123-128.
28. Höller, U., A.D. Wright, G..F. Matthée, G.M. König, S. Draeger, H.-J. Aust and B. Schulz. 2000. Fungi from marine sponges: diversity, biological activity and secondary metabolites. Mycol. Res. 104: 1354-1365.
29. Hsieh, S.-Y., G.F. Yuan and H.S. Chang. 2002. Higher marine fungi from Taiwan. Taiwan Food Technology Industry Research and Development Institute.
30. Huang, H.R., X.K. Xia, Z.G. She, Y.C. Lin, L.L.P. Vrijmoed and E.B.G. Jones. 2004. 1-(2, 6-Dihydroxyphenyl)ethanone. Acta Cryst. E60: o2509-o2511.
31. Huang, H.R., Y.C. Lin, S.N. Zhou and L.L.P. Vrijmoed. 2005a. Metabolites of mangrove endophytic fungus 3920 from the South China Sea. J. Sun Yat-sen Univ. (Nat. Sci.). 44: 137-138.
32. Huang, H.R., X.L. Feng, Z.G. She, Y.C. Lin, L.L.P. Vrijmoed and E.B.G. Jones. 2005b. 1-(2, 6-Dihydroxyphenyl)butanone. Acta Cryst. E61: o282-o284.
33. Huang, H.R., X.K. Xue, Z.G. She, Y.C. Lin, L.L.P. Vrijomed and E.B.G. Jones. 2006. A new chloro-monoterpene from the mangrove endophytic fungus Tryblidiopycnis sp. (4257). J. Asian Nat. Prod. Res. 8: 609-613.
34. Inderbitzin, P., M.A. Abdel-Wahab, E.B.G. Jones and L.L.P. Vrijmoed. 1999. A new species of Cryptovalsa from Mai Po mangroves in Hong Kong. Mycol. Res. 103: 1628-1630.
35. Isaka, M., P. Kottakoop, K. Kirtikara, N.L. Hywel-Jones and Y. Thebtaranonth. 2005. Bioactive substances from insect pathogenic fungi. Acc. Chem. Res. 38: 813-823.
36. Jensen, P.R. and W. Fenical. 2002. Secondary metabolites from marine fungi. In: (K.D. Hyde, ed.) Fungi in marine environments. Fungal Diversity Research Series, Vol. 7. Fungal Diversity Press, Chiang Mai. pp. 293-315.
37. Jiang, G.C., Y.C. Lin, S.N. Zhou, L.L.P. Vrijmoed and E.B.G. Jones. 2000. Studies on the secondary metabolites of mangrove fungus No. 1403 from the South China Sea. J. Sun Yat-sen Univ. (Nat. Sci.) 39: 68-72.
38. Jones, E.B.G. and L.L.P. Vrijmoed. 2003. Biodiversity of marine fungi in Hong Kong coastal waters. In: (B. Morton, ed.) Perspectives on marine environment change in Hong Kong and Southern China 1977-2001. Proceedings of an International Workshop Reunion Conference, Hong Kong. Hong Kong University Press, Hong Kong. pp. 75-92.
39. Jones, E.B.G., M.A. Abdel-Wahab, S.A. Alias and S.-Y. Hsieh. 1999. Dactylospora mangrovei sp. nov. (Discomycetes, Ascomycota) from mangrove wood. Mycoscience 40: 317-320.
40. Jones, E.B.G., I. Chatmala and K.-L. Pang. 2006a. Two new genera isolated from marine habitats in Thailand: Pseudolignincola and Thalespora (Halosphaeriales, Ascomycota). Nova Hedwigia 83: 219-232.
41. Jones, E.B.G., Pilantanapak, A., Chatmala, I., Sakayaroj, J., Phongpaichit, S. and R. Choeyklin. 2006b. Thai marine fungal diversity. Songklanakarin J. Sci. Technol. 28: 687-708.
42. Karl, D.M. 1995. The microbiology of deep-sea hydrothermal vents. CRC Press, Boca Raton. pp. 299.
43. Komatsu, K., H. Shigemori, Y. Mikami and J. Kobayashi. 2001. Dictyonamides A and B, two new peptides from marinederived fungus. J. Org. Chem. 66: 6189-6192.
44. Krohn, K. and M. Riaz. 2004. Total synthesis of (q)-xyloketal D, a secondary metabolite from the mangrove fungus Xylaria sp. Tetrahedron Lett. 45: 293-294.
45. Krohn, K., M. Riaz and U. Florke. 2004. Synthesis of xyloketals, natural products from the mangrove fungus Xylaria sp. Eur. J. Org. Chem. 6: 1261-1270.
46. Kulik, T., A. Pszczółkowska, G. Fordoński and J. Olszewski. 2007. PCR approach based on the esyn1 gene for the detection of potential enniatin-producing Fusarium species. Int. J. Food Microbiol. 116: 319-324.
47. Le, C.G. and Y.C. Lin. 2006. Metabolites of marine fungus Julella avicenniae from South China Sea (II). Zhong Cao Yao [Chinese Traditional and Herbal Drugs] 37: 16-18 (in Chinese).
48. Li, C.Y., R.Y. Yang, Y.C. Lin and S.N. Zhou. 2006. Isolation and crystal structure of (-)-byssochlamic acid from mangrove fungus (strain No. K38). Chem. Nat. Compd. 42: 920-923.
49. Li, C.Y., R.Y. Yang, Y.C. Lin, Z.G. She and S.N. Zhou. 2007. A new nonadride derivative from mangrove fungus (strain no. K38). J. Asian Nat. Prod. Res. 9: 285-291.
50. Li, H.J., Y.C. Lin, L. Wang L, S.N. Zhou and L.L.P. Vrijmoed. 2001. Metabolites of marine fungus Hypoxylon oceanicum from the South China Sea. J. Sun Yat-sen Univ. (Nat. Sci.) 40: 70-73.
51. Li, H.J., Y.C. Lin, J.H. Yao, L.L.P. Vrijmoed and E.B.G. Jones. 2004. Two new metabolites from the mangrove endophytic fungus No. 2524. J. Asian Nat. Prod. Res. 6: 185-191.
52. Li, H.J., W.J. Lan, J.H. Yao and Y.C. Lin. 2005a. High performance liquid chromatography-electrospray ionization tandem mass spectrometry confirms the sequences of new cyclic peptides produced by marine microorganism. Chin. J. Instrument. Anal. 24: 46-49.
53. Li, H.J., W.J. Lan and Y.C. Lin. 2005b. Biotransformation of 1,2,3,4-tetrahydronaphthalene by marine fungus Hypoxylon oceanicum. Chin. J. Instrument. Anal. 24: 45-47.
54. Lin, Y.C. and S.N. Zhou. 2003. Marine microorganisms and their metabolites. Chemical Industry Press, Beijing.
55. Lin, Y.C., Z.Y. Shao, G.C. Jiang, S.N. Zhou, J.W. Cai, L.L.P. Vrijmoed and E.B.G. Jones. 2000. Penicillazine, a unique quinolone derivative with 4H-5,6-dihydro-1,2-oxazine ring system from the marine fungus Penicillium sp. (strain 386) from the South China Sea. Tetrahedron 56: 9607-9609.
56. Lin, Y.C., X.Y. Wu, S. Feng, G.C. Jiang, S.N. Zhou, L.L.P. Vrijmoed and E.B.G. Jones. 2001a. A novel N-cinnamoylcyclopeptide containing an allenic ether from the fungus Xylaria sp. (strain #2508) from the South China Sea. Tetrahedron Lett. 42: 449-451.
57. Lin, Y.C., X.Y. Wu, S. Feng, G.C. Jiang, J.H. Luo, S.N. Zhou, L.L.P. Vrijmoed, E.B.G. Jones, K. Krohn, K. Steingrover and F. Zsila. 2001b. Five unique compounds: Xyloketals from mangrove fungus Xylaria sp. from the South China Sea Coast. J. Org. Chem. 66: 6252-6256.
58. Lin, Y.C., J. Wang, S.N. Zhou and E.B.G. Jones. 2001c. New isocoumarins from the mangrove endophytic fungus #2533. Chem. J. Internet 3: 406-410.
59. Lin, Y.C., J. Wang, X.Y. Wu, S.N. Zhou, L.L.P. Vrijmoed and E.B.G. Jones. 2002a. A novel compound, enniatin G, from the mangrove fungus Halosarpheia sp. (strain 732) from the South China Sea. Aust. J. Chem. 55: 225-227.
60. Lin, Y.C., H.J. Li, G.C. Jiang, S.N. Zhou, L.L.P. Vrijmoed and E.B.G. Jones. 2002b. A novel γ-lactone, eutypoid-a, and other metabolites from marine fungus Eutypa sp. (#424) from the South China Sea. Indian J. Chem. 41: 1542.
61. Liu, X.H., F. Xu, Y. Zhang, L.H. Liu, X.L. Cai, Y.C. Lin and W. Chan. 2006. Xyloketal H from the mangrove endophytic fungus Xylaria sp. 2508. Russ. Chem. Bull. Int. Ed. 55: 1-2.
62. Long, R.A. and F. Azam. 2001. Antagonistic interactions among marine pelagic bacteria. Appl. Environ. Microbiol. 67: 4975-4983.
63. Luo, J.H., Y.B. Yang, Y.C. Lin, Z.L. Chen and X.Y. Wu. 2004a. Effects of metabolites of mangrove fungus Xylaria sp. from South China Sea Coast on the activity of acetylcholinesterase in vitro. Zhong Yao Cai [Chinese Traditional and Herbal Drugs] 27: 261-264.
64. Luo, J.H., Y.B. Yang, Y.C. Lin, Z.L. Chen and G.C. Jiang. 2004b. Antioxidative activities of two metabolites of cultured marine fungus, Halorosellinia oceanicum 323 in vitro. Zhong Yao Cai [Chinese Traditional and Herbal Drugs] 17: 188-192.
65. Luo, J.H., Y.B. Yang, Y.C. Lin, G.C. Jiang and Z.L. Chen. 2004c. Effects of two metabolites of cultured marine fungus, Halorosellinia oceanicum 323, on the contraction of isolated guinea-pig ileum. Yao Xue Xue Bao [Acta Pharm. Sin.] 39: 586-590.
66. McKee, T.C., H.R. Bokesch, J.L. McCormick and M.A. Rashid. 1997. Isolation and characterization of new anti-HIV and cytotoxic leads from plants, marine, and microbial organisms. J. Nat. Prod. 60: 431-433.
67. Miikka P., C. Hekim, P. Soininen, J. Leinonen, H. Koistinen, J. Weisell, Ulf-Håkan Stenman, J. Vepsäläinen and A. Närvänen. 2007. Activity and stability of human kallikrein-2-specific linear and cyclic peptide inhibitors. J. Pept. Sci. 13: 348-353.
68. Pang, K.-L., L.L.P. Vrijmoed, T.K. Goh, N. Plaingam and E.B.G. Jones. 2008. Fungal endophytes associated with Kandelia candel (Rhizophoraceae) in Mai Po Nature Reserve, Hong Kong. Bot. Mar. 51: 171-178.
69. Peres, V., T.J. Nagem and F.F. de Oliveira. 2000. Tetraoxygenated naturally occurring xanthones. Phytochemistry 55: 683.
70. Pettigrew, J.D., R.F. Freeman and P.D. Wilson. 2004a. Total synthesis of (-)-xyloketal D and its enantiomer - confirmation of absolute stereochemistry. Can. J. Chem. 82: 1640-1648.
71. Pettigrew, J.D., J.A. Bexrud, R.P. Freeman and P.D. Wilson. 2004b. Total synthesis of (±)-xyloketal D and model studies towards the total synthesis of (-)-xyloketal A. Heterocycles 62: 445-452.
72. Pettigrew, J.D., J.A. Cadieux, S.S. Siom and P.D. Wilson. 2005. Phenylboronic acid mediated triple condensation reactions of phloroglucinol and unsaturated carbonyl compounds. Org. Lett. 7: 467-470.
73. Pettigrew, J.D. and P.D. Wilson. 2006a. Synthesis of xyloketal A, B, C, D, and G analogues. J. Org. Chem. 71: 1620-1625.
74. Pettigrew, J.D. and P.D. Wilson. 2006b. Total synthesis of (-)-xyloketal A. Org. Lett. 8: 1427-1429.
75. Rodriques, K.F. and O. Petrini. 1997. Biodiversity of endophytic fungi in tropical regions. In: (K.D. Hyde, ed.). Biodiversity of tropical fungi. Hong Kong University Press, Hong Kong. pp. 57-69.
76. Romero, M., I. Sanchez and M.D. Pujol. 2003. New advances in the field of calcium channel antagonists: Cardiovascular effects and structure-activity relationships. Curr. Med. Chem. Cardiovasc. Hematol. Agents 1: 113-141.
77. Sakayaroj, J., E.B.G. Jones, I. Chatmala and S. Phongpaichit. 2004. Marine fungi. In: (E.B.G. Jones, M. Tanticharorn and K.D. Hyde, eds.) Thai fungal diversity. BIOTEC, Thailand. pp. 107-117.
78. Sang, H.S., S.Y. Kang, K.Y. Lee, M.J. Park, J.H. Kim, J.H. Park, Y.C. Kin, J. Kim and Y.C. Kim. 2002. (+)-α-Viniferin, a stilbene trimer from Caragana chamlague, inhibits acetylcholinesterase. Biol. Pharm. Bull. 25: 125-127.
79. Schulz, B., C. Boyle, S. Draeger, A.-K. Römmert and K. Krohn. 2002. Endophytic fungi: a source of biologically active secondary metabolites. Mycol. Res. 106: 996-1004.
80. Shao, Z.Y., Y.C. Lin, G.C. Jiang, S.N. Zhou, L.L.P. Vrijmoed and E.B.G. Jones. 1999. The novel compound with the skeleton of furanopyran from marine fungus from the South China Sea. J. Sun Yat-sen Univ. (Nat. Sci.) 38: 131-132.
81. 13C NMR assignments for two anthraquinones and two xanthones from the mangrove fungus (ZSUH-36). Magn. Reson. Chem. 45: 434-438.
82. Song, J., Y.C. Lin, Y.S. Szeto and W.L. Chan. 2006a. A convenient method for the synthesis of 7,8-dimethoxy-3-hydroxyquinolin-2(1H)-one and its tautomer conformation study. Heterocycles 68: 1185-1190.
83. Song, J., Y.C. Lin, Y.S. Szeto and W.L. Chan. 2006b. Hetero-Diels-Alder reaction of ethyl 2-nitrosoacrylate and cyclohexadienes, and bromine induced diene isomerization. Heterocycles 68: 1685-1689.
84. Stadler, M. and V. Hellwig. 2005. Chemotaxonomy of the Xylariaceae and remarkable bioactive compounds from Xylariales and their associated asexual stages. Recent Res. Dev. Phytochem. 9: 41-93.
85. Strobel, G.A. 2003. Endophytes as sources of bioactive products. Microbes Infect. 5: 535-544.
86. Strongman, D.B., G.M. Strunz, P. Giguere, C.M. Yu and L. Calhoun. 1988. Enniatins from Fusarium avenaceum isolated from balsam fir foliage and their toxicity to spruce budworm larvae, Choristoneura fumiferana (Clem.) (Lepidoptera: Tortricidae). J. Chem. Ecol. 14: 753-764.
87. Takao, K.-i, T., H.Yasui, S. Yamamoto, D. Sasaki, S. Kawasaki, G. Watanabe and K.-I. Tadano. 2004. Asymmetric total syntheses of (+)-mycoepoxydiene and related natural product (-)-1893A: Application of one-pot ring-opening/cross/ring-closing metathesis to construct their 9-oxabicyclo [4.2.1]nona-2,4-diene skeleton. J. Org. Chem. 69: 8789-8795.
88. Tomoda, H., H. Nishida, X. Huang, R. Masuma, Y.K. Kim and S. Omura. 1992a. New cyclodepsipeptides, enniatins D, E, and F produced by Fusarium sp. FO-1305. J. Antibiot. 45: 1207-1215.
89. Tomoda, H., X.H. Huang, J. Cao, H. Nishida, R. Nagao, S. Okuda, H. Tanaka, S. Omura, H. Arai and K. Inoue. 1992b. Inhibition of acyl-CoA: cholesterol acyltransferase activity by cyclodepsipeptide antibiotics. J. Antibiot. 45: 1626-1632.
90. Visconti, A., L.A. Blais, J.W. Apsimon, R. Greenhalgh and J.D. Miller. 1992. Production of enniatins by Fusarium acuminatum and Fusarium compactum in liquid culture: isolation and characterization of three new enniatins, B2, B3, and B4. J. Agric. Food Chem. 40: 1076-1082.
91. Vrijmoed, L.L.P. 2002. Isolation and culture of higher filamentous fungi. In: (K.D. Hyde and S.B. Pointing, eds.) Marine mycology - a practical approach. Fungal Diversity Research Series, Vol. 1. Fungal Diversity Press, Chiang Mai. pp. 1-18.
92. Vrijmoed, L.L.P., I.J. Hodgkiss and L.B. Thrower. 1982. Factors affecting the distribution of lignincolous marine fungi of Hong Kong. Hydrobiologia 87: 143-160.
93. Vrijmoed, L.L.P., K.D. Hyde and E.B.G. Jones. 1994. Observations on mangrove fungi from Macau and Hong Kong, with the description of two new ascomycetes: Diaporthe salsuginosa and Aniptodera haispora. Mycol. Res. 98: 699-704.
94. Vrijmoed, L.L.P., E.B.G. Jones and K.D. Hyde. 1996. Melaspilea mangrovei sp. nov., from Australia and Hong Kong mangroves. Mycol. Res. 100: 291-294.
95. Wang, J., Z.G. She, G.C. Jiang, Y.C. Lin and L.L.P. Vrijmoed. 2005. The secondary metabolites of the marine fungus No.2492 from the mangrove Phragmites australi of the South China Sea. J. Sun Yat-sen Univ. (Nat. Sci.) 44: 132-134.
96. Wen, L., Y.C. Lin, L.B. Zhao, Z.G. She, X.L. Cai and Z.H. Zheng. 2006. Metabolites of marine fungus Paecilomyces sp. tree 1-7 from the South China Sea. Zhong Yao Cai [Chinese Traditional and Herbal Drugs] 29: 782-785.
97. Wen, L., D.S. Du, L. Fan, Z.G. She, Y.C. Lin and Z.H. Zheng. 2007. Studies on the secondary metabolites of a marine mangrove fungus Paecilomyces sp. tree 1-7. J. Sun Yat-sen Univ. (Nat. Sci.) 46: 105-107.
98. Wen, L., Y.C. Lin, Z.G. She, D.S. Du, W.L. Chan and Z.H. Zheng. 2008. Paeciloxanthone, a new cytotoxic xanthone from the marine mangrove fungus Paecilomyces sp. (tree 1-7). J. Asian Nat. Prod. Res. 10: 133-137.
99. Wu, X.Y., X.H. Liu, Y.C. Lin, J.H. Luo, Z.G. She, H.J. Li, W.L. Chan, S. Antus, T. Kurtan, B. Elsasser and K. Krohn. 2005a. Xyloketal F: a strong L-calcium channel blocker from the mangrove fungus Xylaria sp. (#2508) from the South China Sea Coast. Eur. J. Org. Chem. 19: 4061-4064.
100. Wu, X.Y., X.H. Liu, G.C. Jinag, Y.C. Lin, W. Chan and L.L.P. Vrijmoed. 2005b. Xyloketal G, a novel metabolite from the mangrove fungus Xylaria sp. 2508. Chem. Nat. Compd. 41: 27-29.
101. 13C NMR assignments for five anthraquinones from the mangrove endophytic fungus Halorosellinia sp. (No. 1403). Magn. Reson. Chem. 45: 1006-1009.
102. Xia, X.K., H.R. Huang, Z.G. She, J.W. Cai, L. Lan, J.Y. Zhang, L.W. Fu, L.L.P. Vrijmoed and Y.C. Lin. 2007b. Structural and biological properties of vermistatin and two new vermistatin derivatives isolated from the marine-mangrove endophytic fungus Guignardia sp. No. 4382. Helv. Chim. Acta 90: 1925-1931.
103. Yang, R.Y., C.Y. Li, Y.C. Lin, G.T. Peng, Z.G. She and S.N. Zhou. 2006. Lactones from a brown alga endophytic fungus (no. ZZF36) from the South China Sea and their antimicrobial activities. Bioorg. Med. Chem. Lett. 16: 4205-4208.
104. Yin, W.Q., Y.C. Lin, S.N. Zhou and L.L.P. Vrijmoed. 2002. The cyclopeptides from marine fungus 2516 from the South China Sea. J. Sun Yat-sen Univ. (Nat. Sci.). 41: 56-58.
105. Yin, W.Q., J.M. Zhou, Z.G. She, L.L.P. Vrijmoed, E.B.G. Jones and Y.C. Lin. 2005. Two cyclic peptides produced by the endophytic fungus # 2221 from Castaniopsis fissa on the South China Sea Coast. Chin. Chem. Lett. 16: 219-222.
106. Zhu, F. and Y.C. Lin. 2006. A new alkaloid marinamide and its ester derivative produced by mixed-fermentation of two mangrove fungi #1924 and #3893 from the South China Sea. Chin. Sci. Bull. 51: 792-795.
107. Zhu, F., Y.C. Lin, S.N. Zhou and L.L.P. Vrijmoed. 2003. Sterigmatocystin isolated from mangrove endophytic fungus No.2526. Chin. J. Appl. Chem. 20: 272-274.
108. Zhu, F., Y.C. Lin and S.N. Zhou. 2004. Anthraquinone derivatives isolated from marine fungus #2526 from the South China Sea. Chin. J. Org. Chem. 24: 1114-1117.
109. Zhu, F., Y.C. Lin, J. Wang, S.N. Zhou and L.L.P. Vrijmoed. 2005. Metabolites of a mangrove endophytic fungus Stysanus-like sp. from the South China Sea. Chin. J. Chem. Res. Appl. 17: 790-792.
110. Zuccaro, A., B. Schulz and J.I. Mitchell. 2003. Molecular detection of ascomycetes associated with Fucus serratus. Mycol. Res. 107: 1451-1466.