Intramedullary application of bone morphogenetic protein in the management of a major bone defect after an Ilizarov procedure

Journal of Bone and Joint Surgery - Series B

Volumn 90, Issue 6, 2008, Pages 806-809

  Burkhart, K J ^a   Rommens, P M ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT OSTEOGENIC PROTEIN 1;

ACHILLES TENDON; ANAMNESIS; ARTICLE; BONE BIOPSY; BONE DEFECT; BONE NECROSIS; BONE REGENERATION; BONE REMODELING; CASE REPORT; FEMALE; FRACTURE EXTERNAL FIXATION; FRACTURE HEALING; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; ILIZAROV TECHNIQUE; INTRAMEDULLARY NAILING; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; SCHOOL CHILD; TIBIA; TIBIA OSTEOTOMY; WOUND HEALING;

BONE MORPHOGENETIC PROTEINS; BONE NEOPLASMS; CHILD; FEMALE; FRACTURES, STRESS; HUMANS; ILIZAROV TECHNIQUE; LEG LENGTH INEQUALITY; OSTEOGENESIS, DISTRACTION; RECOMBINANT PROTEINS; RHABDOMYOSARCOMA; TIBIA; TIBIAL FRACTURES; TRANSFORMING GROWTH FACTOR BETA;

EID: 45549099791     PISSN: 0301620X     EISSN: None     Source Type: Journal    
DOI: 10.1302/0301-620X.90B6.20147     Document Type: Article

References (22)

1. Hansen M, Mehler D, Rommens P. Das biomechanische Verhalten winkelstabiler Implantatsysteme an der proximalen Tibia. Bern: Verlag Hans Huber, 2004;110 (in German).
2. Laflamme GY, Heimlich D, Stephen D, Kreder HJ, Whyne CM. Proximal tibial fracture stability with intramedullary nail fixation using oblique interlocking screws. J Orthop Trauma 2003;17:496-502.
3. Ilizarov GA. Clinical application of the tension-stress effect for limb lengthening. Clin Orthop 1990;250:8-26.
4. Raschke MJ, Mann JW, Oedekoven G, Claudi BF. Segmental transport after unreamed intramedullary nailing: preliminary report of a "Monorail" system. Clin Orthop 1992;282:233-40.
5. Robert Rozbruch S, Weitzmann AM, Tracy Watson J, et al. Simultaneous treatment of bone and soft-tissue defects with the Ilizarov method. J Orthop Trauma 2006;20:197-205.
6. Kocaoglu M, Eralp L, Rashid HU, Sen C, Bilsel K. Reconstruction of segmental defects due to chronic osteomyelitis with use of an external fixator and an intramedullary nail. J Bone Joint Surg [Am] 2006;88-A.2137-45.
7. Kuhn S, Hansen M, Rommens PM. Extending the indication of intramedullary nailing of tibial fractures. Eur J Trauma Emerg Surg 2007;33:159-69.
8. Dimitriou R, Dahabreh Z, Katsoulis E, et al. Application of recombinant BMP-7 on persistant upper and lower limb non-unions. Injury 2005;36(2Suppl):51-9.
9. Ronga M, Baldo F, Zappala G, Cherubino P. Recombinant human bone morphogenetic protein-7 for treatment of long bone non-union: an observational, retrospective, non-randomized study of 105 patients. Injury 2006;37(Suppl):51-6.
10. Friedlaender GE, Perry CR, Cole JD, et al. Osteogenic protein-1 (bone morphogentic protein-7) in the treatment of tibial nonunions: a prospective, randomized clinical trial comparing rhOP-1 with fresh bone autograft. J Bone Joint Surg [Am] 2001;83-A(Suppl 1):151-8.
11. Fabeck L, Ghafil D, Gerroudj M, Baillon R, Delincé Ph. Bone morphogenetic protein 7 in the treatment of congenital pseudarthrosis of the tibia. J Bone Joint Surg [Br] 2006;88-B:116-18.
12. Pluhar GE, Turner AS, Pierce AR, Toth CA, Wheeler DL. A comparison of two carriers for osteogenic protein-1 (BMP-7) in an ovine critical defect model. J Bone Joint Surg [Br] 2006;88-B:960-6.
13. Obert L, Deschaseaux F, Garbuio P. Critical analysis and efficacy of BMPs in long bones non-union. Injury 2005;36(Suppl):38-42.
14. Urist MR. Bone: formation by autoinduction. Science 1965;698:893-9.
15. Johnson EE, Urist MR. One stage lengthening of femoral non-union augmented with human bone morphogenetic protein. Clin Orthop 1998;347:105-16.
16. Watanabe K, Tsuchiya H, Sakurakichi K, Tomita K. Bone transport using hydroxapatite loaded with bone morphogenetic protein in rabbits. J Bone Joint Surg [Br] 2007;89-B:1122-9.
17. Hammer TO, Wieling R, Green JM, et al. Effect of reimplanted particles from intramedullary reaming on mechanical properties and callus formation: a laboratory study. J Bone Joint Surg [Br] 2007;89-B:1534-8.
18. Frolke JP, Bakker FC, Patka P, Haarmann HJ. Reaming debris in osteotomized sheep tibiae. J Trauma 2001;50:65-70.
19. Wenisch S, Trinkaus K, Hild A, et al. Human reaming debris: a source of multipotent stem cells. Bone 2005;36:74-83.
20. Weresh MJ, Hakanson R, Stover MD, et al. Failure of exchange reamed intramedullary nails for ununited femoral shaft fractures. J Orthop Trauma 2000;14:335-8.
21. Banaszkiewicz PA, Sabboubeh A, McLeod I, Maffulli N. Femoral exchange nailing for aseptic non-union: not the end to all problems. Injury 2003;34:349-56.
22. Court-Brown CM, Keating JF, Christie J, McQueen MM. Exchange intramedullary nailing: its use in aseptic tibial non-union. J Bone Joint Surg [Br] 1995;77-B:407-11.