New protein clustering of breast cancer tissue proteomics using actin content as a cellularity indicator

Journal of Proteome Research

Volumn 7, Issue 4, 2008, Pages 1412-1418

  Pucci Minafra, Ida ^a,b,d   Cancemi, Patrizia ^a   Albanese, Nadia Ninfa ^a   Cara, Gianluca Di ^a   Marabeti, Maria Rita ^a   Marrazzo, Antonio ^a,c   Minafra, Salvatore ^a,b  

^a UNIVERSITY OF PALERMO   (Italy)

^b Centro di Oncobiologia Sperimentale   (Italy)

^c LA MADDALENA CANCER CENTER   (Italy)

^d Dipartimento di Oncologia Sperimentale e Applicazioni Cliniche   (Italy)

Author keywords

Breast cancer; Cellularity indicator; Peptide mass fingerprint; Protein cluster; Proteomic; Surgical tissues; Two dimensional electrophoresis

Indexed keywords

ACTIN; ANNEXIN; BIOLOGICAL MARKER; CALCIUM BINDING PROTEIN; CATHEPSIN D; COFILIN; DIMETHYLARGINASE 2; DJ 1 PROTEIN; GALECTIN 1; GLYCOLYTIC ENZYME; HEAT SHOCK PROTEIN; PROTEIN S 100; PSORIASIN; UNCLASSIFIED DRUG; VINCULIN; PROTEOME;

ARTICLE; BREAST CANCER; CANCER DIAGNOSIS; CELL DENSITY; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS; BREAST TUMOR; CLUSTER ANALYSIS; FEMALE; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; PEPTIDE MAPPING; REPRODUCIBILITY; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING;

ACTINS; BLOTTING, WESTERN; BREAST NEOPLASMS; CLUSTER ANALYSIS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FEMALE; HUMANS; PEPTIDE MAPPING; PROTEOME; PROTEOMICS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 45549097521     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr700748m     Document Type: Article

References (33)

1. Hinestrosa, M. C.; Dickersin, K.; Klein, P.; Mayer, M.; Noss, K.; Slamon, D.; Sledge, G.; Visco, F. M. Shaping the future of biomarker research in breast cancer to ensure clinical relevance. Nat. Rev. Cancer 2007, 7(4), 309-315.
2. Donegan, W. L. Tumor-related prognostic factors for breast cancer. CA Cancer J. Clin. 1997, 47 (1), 28-51.
3. Goldhirsch, A.; Wood, W. C.; Gelber, R. D.; Coates, A. S.; Thürlimann, B.; Senn, H. J. Meeting highlights: updated international expert consensus on the primary therapy of early breast cancer. J.Clin.Oncol. 2003, 21 (17), 3357-3365.
4. Hussain, S. A.; Palmer, D. H.; Spooner, D.; Rea, D. W. Molecularly targeted therapeutics for breast cancer. BioDrugs 2007, 21 (4), 215-224.
5. Greenman, G.; Stephens, P.; Smith, R.; Gillian, L.; Dalgliesh, G. L.; et al. Patterns of somatic mutation in human cancer genomes. Nature 2007, 446 (7132), 153-158.
6. Malik, K.; Brown, W. Epigenetic gene deregulation in cancer. Br. J. Cancer 2000, 83 (12), 1583-1588.
7. Pucci-Minafra, I.; Cancemi, P.; Marabeti, M. R.; Albanese, N. N.; Di Cara, G.; Taormina, P.; Marrazzo, A. Proteomic profiling of 13 paired ductal infiltrating breast carcinomas and non-tumoral adjacent counterparts. Proteomics Clin. Appl. 2007, 1, 118-129.
8. Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 7 (72), 248-254.
9. Pucci-Minafra, I.; Fontana, S.; Cancemi, P.; Alaimo, G.; Minafra, S. Proteomic patterns of cultured breast cancer cells and epithelial mammary cells. Ann. N.Y. Acad. Sci. 2002, 963, 122-139.
10. Pucci-Minafra, I.; Cancemi, P.; Fontana, S.; Minafra, L.; Feo, S.; Becchi, M.; Freyria, A. M.; Minafra, S. Expanding the protein catalogue in the proteome reference map of human breast cancer cells. Proteomics 2006, 6 (8), 2609-2625.
11. Shevchenko, A.; Wilm, M.; Vorm, O.; Mann, M. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem. 1996, 68 (5), 850-858.
12. Altenberg, B.; Greulich, K. O. Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes. Genomics 2004, 84 (6), 1014-1020.
13. Clements, C. M.; McNally, R. S.; Conti, B. J.; Mak, T. W.; Ting, J. P. DJ-1, a cancer-and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proc. Natl. Acad. Sci. U.S.A. 2006, 103 (41), 15091-15096.
14. Hasegawa, K.; Wakino, S.; Tanaka, T.; Kimoto, M.; Tatematsu, S.; Kanda, T.; Yoshioka, K.; Homma, K.; Sugano, N.; Kurabayashi, M.; Saruta, T.; Hayashi, K. Dimethylarginine dimethylaminohydrolase 2 increases vascular endothelial growth factor expression through Spl transcription factor in endothelial cells. Arlerioscler. Thromb. Vasc. Biol. 2006, 26 (7), 1488-1494.
15. Díaz, V. M.; Hurtado, M.; Thomson, T. M.; Reventos, J.; Paciucci, R. Specific interaction of tissue-type plasminogen activator (t-PA) with annexin II on the membrane of pancreatic cancer cells activates plasminogen and promotes invasion in vitro. Gut 2004, 53 (7), 993-1000.
16. Ortiz-Zapater, E.; Peiró, S.; Roda, O.; Corominas, J. M.; Aguilar, S.; Ampurdanés, C.; Real, F. X.; Navarro, P. Tissue plasminogen activator induces pancreatic cancer cell proliferation by a non-catalytic mechanism that requires extracellular signal-regulated kinase 1/2 activation through epidermal growth factor receptor and annexin A2. Am. J. Pathol. 2007, 170 (5), 1573-1584.
17. Rehman, I.; Cross, S. S.; Azzouzi, A. R.; Catto, J. W.; Deloulme, J. C.; Larre, S.; Champigneuille, J.; Fromont, G.; Cussenot, O.; Hamdy, F. C. S100A6 (Calcyclin) is a prostate basal cell marker absent in prostate cancer and its precursors. Br. J. Cancer 2004, 91 (4), 739-744.
18. Vimalachandran, D.; Greenhalf, W.; Thompson, C.; Luttges, J.; Prime, W.; Campbell, F.; Dodson, A.; Watson, R.; Crnogorac-Jurcevic, T.; Lemoine, N.; Neoptolemos, J.; Costello, E. High nuclear S100A6 (Calcyclin) is significantly associated with poor survival in pancreatic cancer patients. Cancer Res. 2005, 65 (8), 3218-3225.
19. Liu, M.; Oberg, K.; Zhou, Y. Expression and function of vinculin in neuroendocrine tumors. Tumor Biol. 2007, 28 (4), 96-204.
20. Zhang, Y. G.; Du, J.; Tian, X. X.; Zhong, Y. F.; Fang, W. G. Expression of E-cadherin, beta-catenin, cathepsin D, gelatinases and their inhibitors in invasive ductal breast carcinomas. Chin. Med. J. 2007, 120 (18), 1597-1605.
21. Obeid, M.; Tesniere, A.; Ghiringhelli, F.; Fimia, G. M; Apetoh, L; Perfettini, J. L.; Castedo, M.; Mignot, G.; Panaretakis, T.; Casares, N.; Métivier, D.; Larochette, N.; van Endert, P.; Ciccosanti, F.; Piacentini, M.; Zitvogel, L.; Kroemer, G. Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat. Med. 2007, 13 (1), 54-61.
22. Sirover, M. A. New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase. Biochim. Biophys. Acta 1999, 1432 (2), 159-184.
23. Savagner, P. Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition. BioEssays 2001, 23 (10), 912-923.
24. Miles, L. A.; Dahlberg, C. M.; Plescia, J.; Felez, J.; Kato, K.; Plow, E. F. Role of cell-surface lysines in plasminogen binding to cells: identification of alpha-enolase as a candidate plasminogen receptor. Biochemistry 1991, 30 (6), 1682-1691.
25. Kondoh, H.; Lleonart, M. E.; Gil, J.; Wang, J.; Degan, P.; Peters, G.; Martinez, D.; Carnero, A.; Beach, D. Glycolytic enzymes can modulate cellular life span. Cancer Res. 2005, 65 (1), 177-185.
26. Yin, M. Y.; Gao, X. Z.; Wang, Z. Q.; Preisler, H. D. Studies of the proliferation and differentiation of immature myeloid cells in vitro: 4: Preculture proto-oncogene expression and the behaviour of myeloid leukemia cells in vitro. Cell Biochem. Funct. 1991, 9 (1), 39-47.
27. Orosz, F.; Oláh, J.; Ovádi, J. Triosephosphate isomerase deficiency: facts and doubts. IUBMB Life 2006, 58 (12), 703-715.
28. Mesaeli, N.; Phillipson, C. Impaired p53 expression, function, and nuclear localization in calreticulin-deficient cells. Mol. Biol. Cell 2004, 15 (4), 1862-1870.
29. Xu, C.; Zheng, P.; Shen, S.; Xu, Y.; Wei, L.; Gao, H.; Wang, S.; Zhu, C.; Tang, Y.; Wu, J.; Zhang, Q.; Shi, Y. NMR structure and regulated expression in APL cell of human SH3BGRL3. FEBS Lett. 2005, 579 (13), 2788-2794.
30. Al Haddad, S.; Zhang, Z.; Leygue, E.; Snell, L.; Huang, A.; Niu, Y.; Hiller-Hitchcock, T.; Hole, K.; Murphy, L. C.; Watson, P. H. Psoriasin (S100A7) expression and invasive breast cancer. Am. J. Pathol. 1999, 155 (6), 2057-2066.
31. Emberley, E. D.; Murphy, L. C.; Watson, P. H. S100A7 and the progression of breast cancer. Breast Cancer Res. 2004, 6 (4), 153-159.
32. Krop, I.; März, A.; Carlsson, H.; Li, X.; Bloushtain-Qimron, N.; Hu, M.; Gelman, R.; Sabel, M. S.; Schnitt, S.; Ramaswamy, S.; Kleer, C. G.; Enerbäck, C.; Polyak, K. A putative role for psoriasin in breast tumor progression. Cancer Res. 2005, 65 (24), 11326-11334.
33. Toi, M.; Inada, K.; Hoshina, S.; Suzuki, H.; Kondo, S.; Tominaga, T. Vascular endothelial growth factor and platelet-derived endothelial cell growth factor are frequently coexpressed in highly vascularized human breast cancer. Clin. Cancer Res. 1995, 1 (9), 961-964.