Essential role of PKCδ in histone deacetylase inhibitor-induced Epstein-Barr virus reactivation in nasopharyngeal carcinoma cells

Journal of General Virology

Volumn 89, Issue 4, 2008, Pages 878-883

  Lee, Heng Huan ^a   Chang, Shih Shin ^a   Lin, Sue Jane ^b   Chua, Huey Huey ^a   Tsai, Tze Jiun ^a   Tsai, Kevin ^a   Lo, You Chang ^a   Chen, Hong Chen ^c   Tsai, Ching Hwa ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; IMMEDIATE EARLY PROTEIN BZLF1; PROTEIN KINASE C DELTA; TRICHOSTATIN A; 12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; BISINDOLYLMALEIMIDE I; BZLF1 PROTEIN, HERPESVIRUS 4, HUMAN; CARBAZOLE DERIVATIVE; ENZYME INHIBITOR; INDOLE DERIVATIVE; MALEIMIDE DERIVATIVE; PROTEIN KINASE C; TRANSACTIVATOR PROTEIN; VIRUS PROTEIN;

ARTICLE; CARCINOMA CELL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EPSTEIN BARR VIRUS; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; NASOPHARYNX CARCINOMA; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN TRANSPORT; TRANSCRIPTION INITIATION; VIRUS REACTIVATION; CELL NUCLEUS TRANSPLANTATION; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; PHYSIOLOGY; TRANSACTIVATION; TUMOR CELL LINE; VIROLOGY; VIRUS ACTIVATION; VIRUS INFECTION;

HUMAN HERPESVIRUS 4;

CARBAZOLES; CELL LINE, TUMOR; ENZYME INHIBITORS; EPSTEIN-BARR VIRUS INFECTIONS; HERPESVIRUS 4, HUMAN; HISTONE DEACETYLASES; HUMANS; INDOLES; MALEIMIDES; NUCLEAR TRANSFER TECHNIQUES; PROMOTER REGIONS (GENETICS); PROTEIN KINASE C; PROTEIN KINASE C-DELTA; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; VIRAL PROTEINS; VIRUS ACTIVATION;

EID: 45549096221     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.83533-0     Document Type: Article

References (33)

1. Chang, L. K. & Liu, S. T. (2000). Activation of the BRLF1 promoter and lytic cycle of Epstein-Barr virus by histone acetylation. Nucleic Acids Res 28, 3918-3925.
2. Chang, Y., Chang, S. S., Lee, H. H, Doong, S. L., Takada, K. & Tsai, C. H. (2004a). Inhibition of the Epstein-Barr virus lytic cycle by Zta-targeted RNA interference. J Gen Virol 85, 1371-1379.
3. Chang, Y., Lee, H. H., Chang, S. S., Hsu, T. Y., Wang, P. W., Chang, Y. S., Takada, K & Tsai, C. H. (2004b). Induction of Epstein-Barr virus latent membrane protein 1 by a lytic transactivator Rta. J Virol 78, 13028-13036.
4. Chang, Y., Lee, H. H., Chen, Y. T., Lu, J., Wu, S. Y, Chen, C. W., Takada, K & Tsai, C. H. (2006). Induction of the early growth response 1 gene by Epstein-Barr virus lytic transactivator Zta. J Virol 80, 7748-7755.
5. Choi, H. S., Lee, J. H, Park J. G. & Lee, Y. I. (2002). Trichostatin A, a histone deacetylase inhibitor, activates the IGFBP-3 promoter by upregulating Sp1 activity in hepatoma cells: alteration of the Sp1/Sp3/HDAC1 multiprotein complex. Biochem Biophys Res Commun 296, 1005-1012.
6. Chua, H. H., Lee, H. H., Chang, S. S., Lu, C. C, Yeh, T. H., Hsu, T. Y., Chang, T. H., Chang, J. T., Chen, M. R. & other authors (2007). Role of the TSG101 gene in Epstein-Barr virus late gene transcription. J Virol 81, 2459-2471.
7. Constantinescu, S. N., Cernescu, C. D. & Popescu, L. M. (1991). Effects of protein kinase C inhibitors on viral entry and infectivity. FEBS Lett 292, 31-33.
8. Daibata, M., Speck S. H., Mulder, C. & Sairenji, T. (1994). Regulation of the BZLF1 promoter of Epstein-Barr virus by second messengers in anti-immunoglobulin-treated B cells. Virology 198, 446-454.
9. Davie, J. R. (2003). Inhibition of histone deacetylase activity by butyrate. J Nutr 133, 2485S-2493S.
10. Davies, A. H, Grand, R. J., Evans, F. J. & Rickinson, A. B. (1991). Induction of Epstein-Baff virus lytic cycle by tumor-promoting and non-tumor-promoting phorbol esters requires active protein kinase C. J Virol 65, 6838-6844.
11. Deutsch, E., Cohen, A, Kazimirsky, G., Dovrat, S., Rubinfeld, H., Brodie, C. & Sarid, R. (2004). Role of protein kinase C delta in reactivation of Kaposi's sarcoma-associated herpesvirus. J Virol 78, 10187-10192.
12. Emoto, Y, Manome, Y., Meinhardt, G., Kisaki, H., Kharbanda, S., Robertson, M., Ghayur, T., Wong, W. W., Kamen, R. & other authors, (1995). Proteolytic activation of protein kinase C δ by an ICE-like protease in apoptotic cells. EMBO J 14, 6148-6156.
13. Eun, D. W., Ahn, S. H., You, J. S., Park, J. W., Lee, E. K., Lee, H. N., Kang, G. M., Lee, J. C., Choi, W. S. & other authors (2007). PKCε is essential for gelsolin expression by histone deacetylase inhibitor apicidin in human cervix cancer cells. Biochem Biophys Res Commun 354, 769-775.
14. Feng, W. H. & Kenney, S. C. (2006). Valproic acid enhances the efficacy of chemotherapy in EBV-positive tumors by increasing lytic viral gene expression. Cancer Res 66, 8762-8769.
15. Fang, W. H, Israel, B, Raab-Traub, N, Busson, P. & Kenney, S. C. (2002). Chemotherapy induces lytic EBV replication and confers ganciclovir susceptibility to EBV-positive epithetial cell tumors, Cancer Res 62, 1920-1926.
16. House, C. & Kemp, B. E. (1987). Protein kinase C contains a pseudosubstrate prototope in its regulatory domain. Science 238, 1726-1728.
17. Ju, R. & Muller, M. T. (2003). Histone deacetylase inhibitors activate p21(WAF1) expression via ATM. Cancer Res 63, 2891-2897.
18. Kieff, E. & Rickinson, A. B. (2001). Epstein-Barr virus and its replication. In Fields Virology, 4th edn, pp. 2511-2573. Edited by D. M. Knipe & P. M. Howley. Philadelphia, PA: Lippincott Williams & Wilkins.
19. Kim, Y. K, Han, J. W., Woo, Y. N., Chun, J. K., Yoo, J. Y., Cho, E. J., Hong, S., Lee, H. Y., Lee, Y. W. & other authors (2003). Expression of p21(WAF1/Cip1) through Sp1 sites by histone deacetylase inhibitor apicidin requires P1 3-kinase-PKC epsilon signaling pathway. Oncogene 22, 6023-6031.
20. Kim, S., Kang, J. K., Kim, Y. K., Seo, D. W., Ahn, S. H., Lee, J. C., Lee, C. H., You, J. S, Cho, E. J. & other authors (2006). Histone deacetylase inhibitor apicidin induces cyclin E expression through Sp1 sites. Biochem Biophys Res Commun 342, 1168-1173.
21. Kim, Y. H., Lim, J. H., Lee, T. J, Park J. W. & Kwon, T. K. (2007). Expression of cyclin D3 through Sp1 sites by histone deacetylase inhibitors is mediated with protein kinase C-δ (PKC-δ) signal pathway. J Cell Biochem 101, 987-995.
22. Luka, J., Kallin, B. & Klein, G. (1979). Induction of the Epstein-Barr virus (EBV) cvcle in latently infected cells bv n-butyrate. Virology 94, 228-231.
23. Marks, P. A. & Dokmanovic, M. (2005). Histone deacetylase inhibitors: discovery and development as anticancer agents. Expert Opin Investig Drugs 14, 1497-1511.
24. Naranatt P. P., Akula, S. M., Zien, C. A., Krishnan, H. H. & Chandran, B. (2003). Kaposi's sarcoma-associated herpesvirus induces the phosphatidylinositol 3-kinase-PKC-ζ-MEK-ERK signaling pathway in target cells early during infection: implications for infectivity. J Virol 77, 1524-1539.
25. Newton, A. C. (1997). Regulation of protein kinase C. Curr Opin Cell Biol 9, 161-167.
26. Schuster, C., Chasserot-Golaz, S. & Beck G. (1991). Activation of Epstein-Barr virus promoters by a growth-factor and a glucocorticoid. FEBS Lett 284, 82-86.
27. Shirai, Y. & Saito, N. (2002). Activation mechanisms of protein kinase C: maturation, catalytic activation, and targeting. J Biochem (Tokyo) 132, 663-668.
28. Sieczkarski, S. B., Brown, H. A. & Whittaker, G. R. (2003). Role of protein kinase C βII in influenza virus entry via late endosomes. J Virol 77, 460-469.
29. Steinberg, S. F. (2004). Distinctive activation mechanisms and functions for protein kinase Cδ. Biochem J 384, 449-459.
30. Storz, P., Doppler, H. & Toker, A. (2004). Protein kinase Cδ selectively regulates protein kinase D-dependent activation of NF-κB in oxidative stress signaling. Mol Cell Biol 24, 2614-2626.
31. Yamamoto, T., Matsuzaki, H., Kamada, S., Ono, Y. & Kikkawa, U. (2006). Biochemical assays for multiple activation states of protein kinase C. Nat Protoc 1, 2791-2795.
32. Ye, J., Shedd, D. & Miller, G. (2005). An Sp1 response element in the Kaposi's sarcoma-associated herpesvirus open reading frame 50 promoter mediates lytic cycle induction bv butvrate. J Virol 79, 1397-1408.
33. Yokota, T., Matsuzaki, Y., Miyazawa, K, Zindy, F., Roussel, M. F. & Sakai, T. (2004). Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter. Oncogene 23, 5340-5349.