Interleukin-15 and interleukin-15Rα SNPs and associations with muscle, bone, and predictors of the metabolic syndrome

Cytokine

Volumn 43, Issue 1, 2008, Pages 45-53

  Pistilli, Emidio E ^a   Devaney, Joseph M ^b   Gordish Dressman, Heather ^b   Bradbury, Margaret K ^b   Seip, Richard L ^c   Thompson, Paul D ^c   Angelopoulos, Theodore J ^d   Clarkson, Priscilla M ^e   Moyna, Niall M ^f   Pescatello, Linda S ^g   Visich, Paul S ^h   Zoeller, Robert F ⁱ   Gordon, Paul M ^j   Hoffman, Eric P ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^c HARTFORD HOSPITAL   (United States)

^d UNIVERSITY OF CENTRAL FLORIDA   (United States)

^e UNIVERSITY OF MASSACHUSETTS   (United States)

^f DUBLIN CITY UNIVERSITY   (Ireland)

^g UNIVERSITY OF CONNECTICUT   (United States)

^h CENTRAL MICHIGAN UNIVERSITY   (United States)

ⁱ FLORIDA ATLANTIC UNIVERSITY   (United States)

^j WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

more..

Author keywords

Cytokines; Metabolic syndrome; Polymorphisms

Indexed keywords

CHOLESTEROL; GLUCOSE; INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR ALPHA; TRIACYLGLYCEROL;

ADULT; ARTICLE; BODY MASS; BONE STRENGTH; CORTICAL BONE; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; MALE; METABOLIC SYNDROME X; MUSCLE MASS; MUSCLE STRENGTH; MUSCLE TRAINING; NORMAL HUMAN; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TRIACYLGLYCEROL BLOOD LEVEL;

ADOLESCENT; ADULT; BONE AND BONES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTERLEUKIN-15; INTERLEUKIN-15 RECEPTOR ALPHA SUBUNIT; MALE; METABOLIC SYNDROME X; MUSCLE, SKELETAL; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 45449108398     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2008.04.008     Document Type: Article

References (51)

1. Fehniger T.A., and Caligiuri M.A. Interleukin 15: biology and relevance to human disease. Blood 97 (2001) 14-32
2. Waldmann T.A., and Tagaya Y. The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens. Annu Rev Immunol 17 (1999) 19-49
3. Grabstein K.H., Eisenman J., Shanebeck K., Rauch C., Srinivasan S., Fung V., et al. Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor. Science 264 (1994) 965-968
4. + T cells. Proc Natl Acad Sci USA 101 (2004) 1969-1974
5. + T cell contraction during primary infection. J Immunol 176 (2006) 507-515
6. Carson W.E., Giri J.G., Lindemann M.J., Linett M.L., Ahdieh M., Paxton R., et al. Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. J Exp Med 180 (1994) 1395-1403
7. Armitage R.J., Macduff B.M., Eisenman J., Paxton R., and Grabstein K.H. IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation. J Immunol 154 (1995) 483-490
8. Nieman D.C., Davis J.M., Brown V.A., Henson D.A., Dumke C.L., Utter A.C., et al. Influence of carbohydrate ingestion on immune changes after 2 h of intensive resistance training. J Appl Physiol 96 (2004) 1292-1298
9. Nieman D.C., Davis J.M., Henson D.A., Walberg-Rankin J., Shute M., Dumke C.L., et al. Carbohydrate ingestion influences skeletal muscle cytokine mRNA and plasma cytokine levels after a 3-h run. J Appl Physiol 94 (2003) 1917-1925
10. Giri J.G., Ahdieh M., Eisenman J., Shanebeck K., Grabstein K., Kumaki S., et al. Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15. EMBO J 13 (1994) 2822-2830
11. Dubois S., Mariner J., Waldmann T.A., and Tagaya Y. IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells. Immunity 17 (2002) 537-547
12. Sato N., Patel H.J., Waldmann T.A., and Tagaya Y. The IL-15/IL-15Ralpha on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cells. Proc Natl Acad Sci USA 104 (2007) 588-593
13. Budagian V., Bulanova E., Paus R., and Bulfone-Paus S. IL-15/IL-15 receptor biology: a guided tour through an expanding universe. Cytokine Growth Factor Rev 17 (2006) 259-280
14. Bulfone-Paus S., Bulanova E., Budagian V., and Paus R. The interleukin-15/interleukin-15 receptor system as a model for juxtacrine and reverse signaling. Bioessays 28 (2006) 362-377
15. Quinn L.S., Haugk K.L., and Grabstein K.H. Interleukin-15: a novel anabolic cytokine for skeletal muscle. Endocrinology 136 (1995) 3669-3672
16. Furmanczyk P.S., and Quinn L.S. Interleukin-15 increases myosin accretion in human skeletal myogenic cultures. Cell Biol Int 27 (2003) 845-851
17. Harcourt L.J., Holmes A.G., Gregorevic P., Schertzer J.D., Stupka N., Plant D.R., et al. Interleukin-15 administration improves diaphragm muscle pathology and function in dystrophic mdx mice. Am J Pathol 166 (2005) 1131-1141
18. Carbo N., Lopez-Soriano J., Costelli P., Busquets S., Alvarez B., Baccino F.M., et al. Interleukin-15 antagonizes muscle protein waste in tumour-bearing rats. Br J Cancer 83 (2000) 526-531
19. Figueras M., Busquets S., Carbo N., Barreiro E., Almendro V., Argiles J.M., et al. Interleukin-15 is able to suppress the increased DNA fragmentation associated with muscle wasting in tumour-bearing rats. FEBS Lett 569 (2004) 201-206
20. Petrovic-Rackov L., and Pejnovic N. Clinical significance of IL-18, IL-15, IL-12 and TNF-alpha measurement in rheumatoid arthritis. Clin Rheumatol 25 (2006) 448-452
21. Ogata Y., Kukita A., Kukita T., Komine M., Miyahara A., Miyazaki S., et al. A novel role of IL-15 in the development of osteoclasts: inability to replace its activity with IL-2. J Immunol 162 (1999) 2754-2760
22. Argiles J.M., Lopez-Soriano J., Almendro V., Busquets S., and Lopez-Soriano F.J. Cross-talk between skeletal muscle and adipose tissue: a link with obesity?. Med Res Rev 25 (2005) 49-65
23. Carbo N., Lopez-Soriano J., Costelli P., Alvarez B., Busquets S., Baccino F.M., et al. Interleukin-15 mediates reciprocal regulation of adipose and muscle mass: a potential role in body weight control. Biochim Biophys Acta 1526 (2001) 17-24
24. Ajuwon K.M., and Spurlock M.E. Direct regulation of lipolysis by interleukin-15 in primary pig adipocytes. Am J Physiol Regul Integr Comp Physiol 287 (2004) R608-R611
25. Quinn L.S., Strait-Bodey L., Anderson B.G., Argiles J.M., and Havel P.J. Interleukin-15 stimulates adiponectin secretion by 3T3-L1 adipocytes: evidence for a skeletal muscle-to-fat signaling pathway. Cell Biol Int 29 (2005) 449-457
26. Almendro V., Busquets S., Ametller E., Carbo N., Figueras M., Fuster G., et al. Effects of interleukin-15 on lipid oxidation: disposal of an oral [(14)C]-triolein load. Biochim Biophys Acta 1761 (2006) 37-42
27. Busquets S., Figueras M., Almendro V., Lopez-Soriano F.J., and Argiles J.M. Interleukin-15 increases glucose uptake in skeletal muscle. An antidiabetogenic effect of the cytokine. Biochim Biophys Acta 1760 (2006) 1613-1617
28. Federation ID. The IDF consensus worldwide definition of the metabolic syndrome. In; 2006.
29. Bierbaum S., Nickel R., Zitnik S., Ahlert I., Lau S., Deichmann K.A., et al. Confirmation of association of IL-15 with pediatric asthma and comparison of different controls. Allergy 61 (2006) 576-580
30. Bierbaum S., Sengler C., Gerhold K., Berner R., and Heinzmann A. Polymorphisms within interleukin 15 are associated with juvenile idiopathic arthritis. Clin Exp Rheumatol 24 (2006) 219
31. Christensen U., Haagerup A., Binderup H.G., Vestbo J., Kruse T.A., and Borglum A.D. Family based association analysis of the IL2 and IL15 genes in allergic disorders. Eur J Hum Genet 14 (2006) 227-235
32. Di Renzo L., Bigioni M., Bottini F.G., Del Gobbo V., Premrov M.G., Cianci R., et al. Normal Weight Obese syndrome: role of single nucleotide polymorphism of IL-1 5Ralpha and MTHFR 677 C → T genes in the relationship between body composition and resting metabolic rate. Eur Rev Med Pharmacol Sci 10 (2006) 235-245
33. Haas D.W., Geraghty D.E., Andersen J., Mar J., Motsinger A.A., D'Aquila R.T., et al. Immunogenetics of CD4 lymphocyte count recovery during antiretroviral therapy: an AIDS Clinical Trials Group study. J Infect Dis 194 (2006) 1098-1107
34. Kurz T., Strauch K., Dietrich H., Braun S., Hierl S., Jerkic S.P., et al. Multilocus haplotype analyses reveal association between 5 novel IL-15 polymorphisms and asthma. J Allergy Clin Immunol 113 (2004) 896-901
35. Riechman S.E., Balasekaran G., Roth S.M., and Ferrell R.E. Association of interleukin-15 protein and interleukin-15 receptor genetic variation with resistance exercise training responses. J Appl Physiol 97 (2004) 2214-2219
36. Warle M.C., Farhan A., Metselaar H.J., Hop W.C., Perrey C., Zondervan P.E., et al. Cytokine gene polymorphisms and acute human liver graft rejection. Liver Transpl 8 (2002) 603-611
37. Devaney J.M., Hoffman E.P., Gordish-Dressman H., Kearns A., Zambraski E., and Clarkson P.M. IGF-II gene region polymorphisms related to exertional muscle damage. J Appl Physiol 102 (2007) 1815-1823
38. Pescatello L.S., Kostek M.A., Gordish-Dressman H., Thompson P.D., Seip R.L., Price T.B., et al. ACE ID genotype and the muscle strength and size response to unilateral resistance training. Med Sci Sports Exerc 38 (2006) 1074-1081
39. Pistilli E.E., Gordish-Dressman H., Seip R.L., Devaney J.M., Thompson P.D., Price T.B., et al. Resistin polymorphisms are associated with muscle, bone, and fat phenotypes in white men and women. Obesity (Silver Spring) 15 (2007) 392-402
40. Thompson P.D., Moyna N., Seip R., Price T., Clarkson P., Angelopoulos T., et al. Functional polymorphisms associated with human muscle size and strength. Med Sci Sports Exerc 36 (2004) 1132-1139
41. Baechle T.R. Essentials of strength training and conditioning (1994), Human Kinetics, Champaign
42. Metter E.J., Lynch N., Conwit R., Lindle R., Tobin J., and Hurley B. Muscle quality and age: cross-sectional and longitudinal comparisons. J Gerontol A Biol Sci Med Sci 54 (1999) B207-B218
43. Keskin M., Kurtoglu S., Kendirci M., Atabek M.E., and Yazici C. Homeostasis model assessment is more reliable than the fasting glucose/insulin ratio and quantitative insulin sensitivity check index for assessing insulin resistance among obese children and adolescents. Pediatrics 115 (2005) e500-e503
44. Uthurralt J., Gordish-Dressman H., Bradbury M., Tesi-Rocha C., Devaney J., Harmon B., et al. PPARalpha L162 V underlies variation in serum triglycerides and subcutaneous fat volume in young males. BMC Med Genet 8 (2007) 55
45. Rueda B., Lopez-Nevot M.A., Gonzalez-Gay M.A., Balsa A., Pascual-Salcedo D., Garcia A., et al. Molecular screening and association study of IL15 gene polymorphisms in rheumatoid arthritis. Cytokine 38 (2007) 84-89
46. Engert J.C., Vohl M.C., Williams S.M., Lepage P., Loredo-Osti J.C., Faith J., et al. 5′ flanking variants of resistin are associated with obesity. Diabetes 51 (2002) 1629-1634
47. Mattevi V.S., Zembrzuski V.M., and Hutz M.H. A resistin gene polymorphism is associated with body mass index in women. Hum Genet 115 (2004) 208-212
48. Ford E.S. Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome: a summary of the evidence. Diabetes Care 28 (2005) 1769-1778
49. Pistilli E.E., Siu P.M., and Alway S.E. Interleukin-15 responses to aging and unloading-induced skeletal muscle atrophy. Am J Physiol Cell Physiol 292 (2007) C1298-C1304
50. Hubal M.J., Gordish-Dressman H., Thompson P.D., Price T.B., Hoffman E.P., Angelopoulos T.J., et al. Variability in muscle size and strength gain after unilateral resistance training. Med Sci Sports Exerc 37 (2005) 964-972
51. Ruiz C., Perez E., Garcia-Martinez O., Diaz-Rodriguez L., Arroyo-Morales M., and Reyes-Botella C. Expression of cytokines IL-4, IL-12, IL-15, IL-18, and IFNgamma and modulation by different growth factors in cultured human osteoblast-like cells. J Bone Miner Metab 25 (2007) 286-292