Glutathione-S -transferase P1, T1 and M1 genetic polymorphisms in neoadjuvant-treated locally advanced gastric cancer: GSTM1-present genotype is associated with better prognosis in completely resected patients

International Journal of Colorectal Disease

Volumn 23, Issue 8, 2008, Pages 773-782

  Ott, Katja ^a   Lordick, Florian ^b   Becker, Karen ^c   Ulm, Kurt ^d   Siewert, Jörg Rüdiger ^b   Höfler, Heinz ^c   Keller, Gisela ^c  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Gastric cancer; GST polymorphisms; Neoadjuvant chemotherapy; Prognosis; Response prediction

Indexed keywords

CISPLATIN; DNA; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; FLUOROURACIL; FOLINIC ACID; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; GLUTATHIONE TRANSFERASE T1; ISOLEUCINE; PACLITAXEL; VALINE;

ADJUVANT THERAPY; ADULT; ADVANCED CANCER; AGED; AMINO ACID SUBSTITUTION; ARTICLE; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE FREE SURVIVAL; DNA ISOLATION; FEMALE; GASTRECTOMY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; INDIVIDUALIZATION; LYMPHADENECTOMY; MAJOR CLINICAL STUDY; MALE; MULTIPLEX POLYMERASE CHAIN REACTION; PATIENT CARE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; STOMACH CANCER; TREATMENT OUTCOME;

ANTINEOPLASTIC AGENTS; CISPLATIN; DISEASE-FREE SURVIVAL; FEMALE; GASTRECTOMY; GENOTYPE; GLUTATHIONE S-TRANSFERASE PI; GLUTATHIONE TRANSFERASE; HUMANS; LYMPH NODE EXCISION; MALE; MIDDLE AGED; NEOADJUVANT THERAPY; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PROGNOSIS; RETROSPECTIVE STUDIES; STOMACH NEOPLASMS;

EID: 45449106593     PISSN: 01791958     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00384-008-0490-4     Document Type: Article

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