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Volumn 37, Issue 5, 2008, Pages 512-513

A simple and efficient protocol for chlorination of baylis-hillman adducts using PPh3/CCl4

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EID: 45449086736     PISSN: 03667022     EISSN: None     Source Type: Journal    
DOI: 10.1246/cl.2008.512     Document Type: Article
Times cited : (9)

References (24)
  • 1
    • 45449118393 scopus 로고    scopus 로고
    • Part 168 in the series, Studies on novel synthetic methodologies.
    • Part 168 in the series, Studies on novel synthetic methodologies.
  • 17
    • 45449107952 scopus 로고    scopus 로고
    • 3 (3mmol) was added. The mixture was stirred under reflux and the progress of the reaction was monitored by TLC. After completion the solvent was evaporated under reduced pressure. The product was extracted with EtOAc (2 × 10 mL), concentrated and chromatographed over silica gel to obtain the corresponding allyl chloride.
    • 3 (3mmol) was added. The mixture was stirred under reflux and the progress of the reaction was monitored by TLC. After completion the solvent was evaporated under reduced pressure. The product was extracted with EtOAc (2 × 10 mL), concentrated and chromatographed over silica gel to obtain the corresponding allyl chloride.
  • 20
    • 45449114893 scopus 로고    scopus 로고
    • The spectral (1HNMR and MS) data of some representative products are given below. 3c: 1HNMR (200 MHz, CDCl3, δ 8.32 (2H, d, J, 8.0Hz, 7.89 (1H, s, 7.70 (2H, d, J, 8.0Hz, 4.35 (2H, s, 4.32 (2H, q, J, 7.0Hz, 1.37 (3H, t, J, 8.0Hz, FABMS: m/z 281, 283, 285 [M, Na, 3g: 1HNMR (200 MHz, CDCl3, δ 7.82 (1H, s, 7.55 (2H, d, J, 8.0Hz, 6.98 (2H, d, J, 8.0Hz, 4.51 (2H, s, 3.86 (6H, s, FABMS: m/z 263, 265 [M, Na, 3i: 1HNMR (200 MHz, CDCl3, δ 7.51 (2H, d, J, 8.0Hz, 7.41 (2H, d, J, 8.0Hz, 7.24 (1H, s, 4.39 (2H, s, 3.88 (3H, s, FABMS: m/z 278, 280 [M, Na, 4k: 1HNMR (200MHz, CDCl3, δ 7.79 (2H,d, J, 8.0 Hz, 7.44 (2H, d, J, 8.0Hz, 7.18 (1H, s, 4.28 2H, s, FABMS: m/z 234, 236, 238 [M, Na
    • +.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.