Convenient and efficient stereoselective synthesis of (2Z)-2-(chloromethyl) alk-2-enoates using iron(III) or indium(III) chloride

Tetrahedron Letters

Volumn 45, Issue 11, 2004, Pages 2425-2426

  Das, Biswanath ^a   Banerjee, Joydeep ^a   Ravindranath, Nasi ^a   Venkataiah, Bollu ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

(2Z) 2 (Chloromethyl)alk 2 enoates; 3 Hydroxy 2 methylene alkanoates; Baylis Hillman adducts; FeCl3; InCl3

Indexed keywords

ALKANE DERIVATIVE; FERROUS CHLORIDE; INDIUM CHLORIDE;

ARTICLE; BAYLIS HILLMAN REACTION; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; REACTION ANALYSIS; ROOM TEMPERATURE; STEREOCHEMISTRY; STRUCTURE ANALYSIS; SYNTHESIS;

EID: 1242293068     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.01.101     Document Type: Article

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14. 3 (0.35 equiv) was added. The mixture was stirred at room temperature and the reaction was monitored by TLC. After completion the solution was decanted, concentrated and subjected to column chromatography over silica gel using hexane-EtOAc (4:1) as eluent to yield the (2Z)-2-(chloromethyl) alk-2-enoates 2.
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