Cloning of a gene cluster responsible for the biosynthesis of diterpene aphidicolin, a specific inhibitor of DNA polymerase α

Bioscience, Biotechnology and Biochemistry

Volumn 68, Issue 1, 2004, Pages 146-152

  Toyomasu, Tomonobu ^a   Nakaminami, Kentaro ^a   Toshima, Hiroaki ^b   Mie, Takashi ^c   Watanabe, Kenji ^c   Ito, Hiroyuki ^c   Matsui, Hirokazu ^c   Mitsuhashi, Wataru ^a   Sassa, Takeshi ^a   Oikawa, Hideaki ^c  

^a YAMAGATA UNIVERSITY   (Japan)

^b IBARAKI UNIVERSITY   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Aphidicolin; Biosynthesis; Diterpene; Gene cluster; Phoma betae

Indexed keywords

APHIDICOLAN 16BETA OL SYNTHASE; APHIDICOLAN-16BETA-OL SYNTHASE; APHIDICOLIN; CARRIER PROTEIN; CYTOCHROME P450; DNA DIRECTED DNA POLYMERASE BETA; ENZYME; FARNESYL TRANS TRANSFERASE; HEME; TRANSCRIPTION FACTOR; TRANSFERASE;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; BIOSYNTHESIS; DEUTEROMYCETES; DRUG ANTAGONISM; GENETICS; METABOLISM; METHODOLOGY; MOLECULAR CLONING; MOLECULAR GENETICS; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; POLYMERASE CHAIN REACTION; PROTEIN MOTIF; SEQUENCE HOMOLOGY;

ALKYL AND ARYL TRANSFERASES; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; APHIDICOLIN; BINDING SITES; CARRIER PROTEINS; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; DNA POLYMERASE I; ENZYMES; FARNESYLTRANSTRANSFERASE; HEME; MITOSPORIC FUNGI; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; OPEN READING FRAMES; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS;

FUNGI IMPERFECTI; PHOMA; PHOMA BETAE;

EID: 4544375555     PISSN: 09168451     EISSN: None     Source Type: Journal    
DOI: 10.1271/bbb.68.146     Document Type: Article

References (37)

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