A peptidomimetic HIV-entry inhibitor directed against the CD4 binding site of the viral glycoprotein gp120

Angewandte Chemie - International Edition

Volumn 43, Issue 22, 2004, Pages 2937-2940

  Neffe, Axel T ^a   Meyer, Bernd ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

Author keywords

Drug design; Molecular recognition; NMR spectroscopy; Peptidomimetics; Viruses

Indexed keywords

BINDING ENERGY; STRUCTURE (COMPOSITION); SYNTHESIS (CHEMICAL);

BINDING AFFINITY; HIV-ENTRY INHIBITORS; PROTEOLYTIC STABILITY;

ENZYME INHIBITION;

ASPARAGINYLMETHIONYLTRYPTOPHYLGLUTAMINYLLYSYLVALYLGLYCYLTHREONYLPROLYL LEUCINE; CD4 ANTIGEN; GLYCOPROTEIN GP 120; PEPTIDE; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN;

ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; BINDING SITE; DRUG BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS; INHIBITION KINETICS; MOLECULAR WEIGHT; PROTEIN DEGRADATION; STRUCTURE ANALYSIS;

ANTI-HIV AGENTS; ANTIGENS, CD4; BIOMIMETIC MATERIALS; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR MIMICRY; PEPTIDES; PROTEIN BINDING; VIRUS REPLICATION;

EID: 4544374723     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200353271     Document Type: Article

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