Controlling chemoselectivity in the lithiation of substituted aromatic tertiary amides

Angewandte Chemie - International Edition

Volumn 43, Issue 16, 2004, Pages 2135-2138

  Armstrong, David R ^b   Boss, Sally R ^a   Clayden, Jonathan ^c   Haigh, Robert ^a   Kirmani, Basel A ^a   Linton, David J ^a   Schooler, Paul ^a   Wheatley, Andrew E H ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Density functional calculations; Directing groups; Lithiation; Reaction mechanisms; Solid state structures

Indexed keywords

DIMERS; MONOMERS; NITROGEN COMPOUNDS; PROBABILITY DENSITY FUNCTION;

CHEMOSELECTIVITY; LITHIATION;

AROMATIC COMPOUNDS;

2 ETHYL N,N DIISOPROPYL 1 BENZAMIDE; ALKALI; AROMATIC AMIDE; BENZAMIDE DERIVATIVE; DIETHYLENETRIAMINE; DIMER; LITHIUM DERIVATIVE; MONOMER; N,N,N',N'',N'' PENTAMETHYLDIETHYLENETRIAMINE; TERT BUTYLLITHIUM; UNCLASSIFIED DRUG;

ARTICLE; DENSITY FUNCTIONAL THEORY; ISOLATION PROCEDURE; LITHIATION; PROTON TRANSPORT; SOLVATION; SUBSTITUTION REACTION;

EID: 4544361332     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200353324     Document Type: Article

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