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Volumn 12, Issue 20, 2004, Pages 5317-5329

Synthesis and biological activities of novel 17-aminogeldanamycin derivatives

(10) Tian, Zong Qiang a Liu, Yaoquan a Zhang, Dan a Wang, Zhan a Dong, Steven D a Carreras, Christopher W a Zhou, Yiqing a Rastelli, Giulio b Santi, Daniel V a Myles, David C a

a KOSAN BIOSCIENCES INC (United States)

b UNIVERSITY OF MODENA AND REGGIO EMILIA (Italy)

Author keywords

17 AAG; 17 Alkylaminogeldanamycin; 17 DMAG; Anti cancer; Geldanamycin; Hsp90

Indexed keywords

17 (2 DIMETHYLAMINOETHYL)AMINO 17 DEMETHOXYGELDANAMYCIN; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; UNCLASSIFIED DRUG; WATER;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL GROWTH; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DRUG ACTIVITY; DRUG POTENCY; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ACTIVITY; GROWTH INHIBITION; HUMAN; HUMAN CELL; MAMMAL CELL; MOLECULAR BIOLOGY; SOLUBILITY;

AMINO ACID SEQUENCE; BENZOQUINONES; CELL LINE, TUMOR; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; MOLECULAR SEQUENCE DATA; QUINONES; RECOMBINANT PROTEINS; SOLUBILITY; WATER;

MAMMALIA;

EID: 4544337503 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2004.07.053 Document Type: Article

Times cited : (156)

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