-
1
-
-
0035814837
-
Thrombus formation on atherosclerotic plaques: Pathogenesis and clinical consequences
-
Rauch U, Osende JI, Fuster V, et al. Thrombus formation on atherosclerotic plaques: pathogenesis and clinical consequences. Ann Intern Med 2001; 134: 224-38.
-
(2001)
Ann. Intern. Med.
, vol.134
, pp. 224-238
-
-
Rauch, U.1
Osende, J.I.2
Fuster, V.3
-
2
-
-
0024794147
-
Simvastatin reduces platelet thromboxane formation and restores normal platelet sensitivity against prostacyclin in type IIa hypercholesterolemia
-
Schror K, Lobel P, Steinhagen-Thiessen E. Simvastatin reduces platelet thromboxane formation and restores normal platelet sensitivity against prostacyclin in type IIa hypercholesterolemia. Eicosanoids 1989; 2: 39-45.
-
(1989)
Eicosanoids
, vol.2
, pp. 39-45
-
-
Schror, K.1
Lobel, P.2
Steinhagen-Thiessen, E.3
-
3
-
-
0033786342
-
Statins and cardiovascular diseases: The multiple effects of lipid-lowering therapy by statins
-
Rauch U, Osende JI, Chesebro JH, et al. Statins and cardiovascular diseases: the multiple effects of lipid-lowering therapy by statins. Atherosclerosis 2000; 153: 181-9.
-
(2000)
Atherosclerosis
, vol.153
, pp. 181-189
-
-
Rauch, U.1
Osende, J.I.2
Chesebro, J.H.3
-
4
-
-
0035843178
-
Identification of the platelet ADP receptor targeted by antithrombotic drugs
-
Hollopeter G, Jantzen HM, Vincent D, et al. Identification of the platelet ADP receptor targeted by antithrombotic drugs. Nature 2001; 409: 202-7.
-
(2001)
Nature
, vol.409
, pp. 202-207
-
-
Hollopeter, G.1
Jantzen, H.M.2
Vincent, D.3
-
5
-
-
0033866132
-
Clopidogrel: A review of its use in the prevention of atherothrombosis
-
Jarvis B, Simpson K. Clopidogrel: a review of its use in the prevention of atherothrombosis. Drugs 2000; 60: 347-77.
-
(2000)
Drugs
, vol.60
, pp. 347-377
-
-
Jarvis, B.1
Simpson, K.2
-
6
-
-
0030590746
-
CAPRIE Steering Committee. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)
-
CAPRIE Steering Committee. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). Lancet 1996; 348: 1329-39.
-
(1996)
Lancet
, vol.348
, pp. 1329-1339
-
-
-
7
-
-
17744374250
-
Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) Study Investigators. The Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) trial programme; rationale, design and baseline characteristics including a meta-analysis of the effects of thienopyridines in vascular disease
-
Mehta SR, Yusuf S; Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) Study Investigators. The Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) trial programme; rationale, design and baseline characteristics including a meta-analysis of the effects of thienopyridines in vascular disease. Eur Heart J 2000; 21: 2033-41.
-
(2000)
Eur. Heart. J.
, vol.21
, pp. 2033-2041
-
-
Mehta, S.R.1
Yusuf, S.2
-
8
-
-
0028083293
-
The anti-aggregating activity of clopidogrel is due to a metabolic activation by the hepatic cytochrome P450-1A
-
Savi P, Combalbert J, Gaich C, et al. The anti-aggregating activity of clopidogrel is due to a metabolic activation by the hepatic cytochrome P450-1A. Thromb Haemost 1994; 72: 313-7.
-
(1994)
Thromb. Haemost.
, vol.72
, pp. 313-317
-
-
Savi, P.1
Combalbert, J.2
Gaich, C.3
-
9
-
-
0346497703
-
Potent mechanism-based inhibition of human CYP2B6 by clopidogrel and ticlopidine
-
Richter T, Murdter TE, Heinkele G, et al. Potent mechanism-based inhibition of human CYP2B6 by clopidogrel and ticlopidine. J Pharmacol Exp Ther 2004; 308: 189-97.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.308
, pp. 189-197
-
-
Richter, T.1
Murdter, T.E.2
Heinkele, G.3
-
10
-
-
0038508970
-
The metabolism of clopidogrel is catalyzed by human cytochrome P450 3A and is inhibited by atorvastatin
-
Clarke TA, Waskell LA. The metabolism of clopidogrel is catalyzed by human cytochrome P450 3A and is inhibited by atorvastatin. Drug Metab Dispos 2003; 31: 53-9.
-
(2003)
Drug Metab. Dispos.
, vol.31
, pp. 53-59
-
-
Clarke, T.A.1
Waskell, L.A.2
-
11
-
-
0037422534
-
Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation. A new drug-drug interaction
-
Lau WC, Waskell LA, Watkins PB, et al. Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation. A new drug-drug interaction. Circulation 2003; 107: 32-7.
-
(2003)
Circulation
, vol.107
, pp. 32-37
-
-
Lau, W.C.1
Waskell, L.A.2
Watkins, P.B.3
-
12
-
-
0042780283
-
Clopidogrel for the Reduction of Events During Observation Investigators. Lack of adverse clopidogrel-atorvastatin clinical interaction from secondary analysis of a randomized, placebo-controlled clopidogrel trial
-
Saw J, Steinhubl SR, Berger PB, et al. Clopidogrel for the Reduction of Events During Observation Investigators. Lack of adverse clopidogrel-atorvastatin clinical interaction from secondary analysis of a randomized, placebo-controlled clopidogrel trial. Circulation 2003; 108: 921-4.
-
(2003)
Circulation
, vol.108
, pp. 921-924
-
-
Saw, J.1
Steinhubl, S.R.2
Berger, P.B.3
-
13
-
-
0035464254
-
Recovery of platelet function after discontinuation of clopidogrel treatment in healthy volunteers
-
Weber AA, Braun M, Hohlfeld T, et al. Recovery of platelet function after discontinuation of clopidogrel treatment in healthy volunteers. Br J Clin Pharmacol 2001; 52: 333-6.
-
(2001)
Br. J. Clin. Pharmacol.
, vol.52
, pp. 333-336
-
-
Weber, A.A.1
Braun, M.2
Hohlfeld, T.3
-
14
-
-
0036890878
-
Increased platelet activation in patients with cardiomyopathy: Myocardial inflammation and platelet reactivity
-
Weikert U, Kuhl U, Schultheiss HP, et al. Increased platelet activation in patients with cardiomyopathy: Myocardial inflammation and platelet reactivity. Platelets 2002; 13: 487-91.
-
(2002)
Platelets
, vol.13
, pp. 487-491
-
-
Weikert, U.1
Kuhl, U.2
Schultheiss, H.P.3
-
15
-
-
0036242793
-
The Ultegra rapid platelet-function assay: Comparison to standard platelet function assays in patients undergoing percutaneous coronary intervention with abciximab therapy
-
Wheeler GL, Braden GA, Steinhubl SR, et al. The Ultegra rapid platelet-function assay: comparison to standard platelet function assays in patients undergoing percutaneous coronary intervention with abciximab therapy. Am Heart J 2002; 143: 602-11.
-
(2002)
Am. Heart. J.
, vol.143
, pp. 602-611
-
-
Wheeler, G.L.1
Braden, G.A.2
Steinhubl, S.R.3
-
16
-
-
0033537494
-
Rapid platelet-function assay: An automated and quantitative cartridge-based method
-
Smith JW, Steinhubl SR, Lincoff AM, et al. Rapid platelet-function assay: an automated and quantitative cartridge-based method. Circulation 1999; 99: 620-5.
-
(1999)
Circulation
, vol.99
, pp. 620-625
-
-
Smith, J.W.1
Steinhubl, S.R.2
Lincoff, A.M.3
-
17
-
-
0035967496
-
Point-of-care measured platelet inhibition correlates with a reduced risk of an adverse cardiac event after percutaneous coronary intervention. Results of the GOLD (AU-assessing Ultegra) multicenter study
-
Steinhubl SR, Talley JD, Braden GA, et al. Point-of-care measured platelet inhibition correlates with a reduced risk of an adverse cardiac event after percutaneous coronary intervention. Results of the GOLD (AU-assessing Ultegra) multicenter study. Circulation 2001; 103: 2572-8.
-
(2001)
Circulation
, vol.103
, pp. 2572-2578
-
-
Steinhubl, S.R.1
Talley, J.D.2
Braden, G.A.3
-
18
-
-
0030832526
-
Reduced platelet aggregation after fluvastatin therapy is associated with altered platelet lipid composition and drug binding to the platelets
-
Hussein O, Rosenblat M, Schlezinger S, et al. Reduced platelet aggregation after fluvastatin therapy is associated with altered platelet lipid composition and drug binding to the platelets. Br J Clin Pharmacol 1997; 44: 77-83.
-
(1997)
Br. J. Clin. Pharmacol.
, vol.44
, pp. 77-83
-
-
Hussein, O.1
Rosenblat, M.2
Schlezinger, S.3
-
19
-
-
0034020163
-
Stimulation of platelets and endothelial cells by mildly oxidized LDL proceeds through activation of lysophosphatidic acid receptors and the Rho/Rho-kinase pathway. Inhibition by lovastatin
-
Essler M, Retzer M, Bauer M, et al. Stimulation of platelets and endothelial cells by mildly oxidized LDL proceeds through activation of lysophosphatidic acid receptors and the Rho/Rho-kinase pathway. Inhibition by lovastatin. Ann N Y Acad Sci 2000; 905: 282-6.
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.905
, pp. 282-286
-
-
Essler, M.1
Retzer, M.2
Bauer, M.3
-
20
-
-
0036118915
-
Pleiotropic effects of HMG-CoA reductase inhibitors
-
Werner N, Nickenig G, Laufs U. Pleiotropic effects of HMG-CoA reductase inhibitors. Basic Res Cardiol 2002; 97: 105-16.
-
(2002)
Basic Res. Cardiol.
, vol.97
, pp. 105-116
-
-
Werner, N.1
Nickenig, G.2
Laufs, U.3
-
21
-
-
10744228675
-
Platelet hyperactivity after statin treatment discontinuation
-
Puccetti L, Pasqui AL, Pastorelli M, et al. Platelet hyperactivity after statin treatment discontinuation. Thromb Haemost 2003; 90: 476-82.
-
(2003)
Thromb. Haemost.
, vol.90
, pp. 476-482
-
-
Puccetti, L.1
Pasqui, A.L.2
Pastorelli, M.3
-
22
-
-
0141986521
-
Lipophilic statins interfere with the inhibitory effects of clopidogrel on platelet function - A flow cytometry study
-
Neubauer H, Gunesdogan B, Hanefeld C, et al. Lipophilic statins interfere with the inhibitory effects of clopidogrel on platelet function - a flow cytometry study. Eur Hear J 2003; 24: 1744-9.
-
(2003)
Eur. Hear. J.
, vol.24
, pp. 1744-1749
-
-
Neubauer, H.1
Gunesdogan, B.2
Hanefeld, C.3
-
23
-
-
1642410985
-
Atorvastatin does not affect the antiplatelet potency of clopidogrel when it is administered concomitantly for 5 weeks in patients with acute coronary syndromes
-
Mitsios JV, Papathanasiou AI, Rodis FI, et al. Atorvastatin does not affect the antiplatelet potency of clopidogrel when it is administered concomitantly for 5 weeks in patients with acute coronary syndromes. Circulation 2004; 109: 1335-8.
-
(2004)
Circulation
, vol.109
, pp. 1335-1338
-
-
Mitsios, J.V.1
Papathanasiou, A.I.2
Rodis, F.I.3
-
24
-
-
0000089239
-
European Working Group on Clinical Cell Analysis: Consensus protocol for the flow cytometric characterisation of platelet function
-
Schmitz G, Rothe G, Ruf A, et al. European Working Group on Clinical Cell Analysis: Consensus protocol for the flow cytometric characterisation of platelet function. Thromb Haemost 1998; 79: 885-96.
-
(1998)
Thromb. Haemost.
, vol.79
, pp. 885-896
-
-
Schmitz, G.1
Rothe, G.2
Ruf, A.3
-
25
-
-
4544368393
-
Atorvastatin does not affect the antiplatelet properties of clopidogrel in patients undergoing coronary stenting in randomized data from the Interaction of Atorvastatin and Clopidogrel (INTERACTION) Trial
-
(abstr)
-
Serebruany VL, Midei MG, Malinin AI, et al. Atorvastatin does not affect the antiplatelet properties of clopidogrel in patients undergoing coronary stenting in randomized data from the Interaction of Atorvastatin and Clopidogrel (INTERACTION) Trial. Eur Hear J Suppl 2003 (abstr).
-
(2003)
Eur. Hear. J. Suppl.
-
-
Serebruany, V.L.1
Midei, M.G.2
Malinin, A.I.3
-
26
-
-
0242298647
-
Effects of statins on platelet inhibition by a high loading dose of clopidogrel
-
Muller I, Besta F, Schulz C, et al. Effects of statins on platelet inhibition by a high loading dose of clopidogrel. Circulation 2003; 108: 2195-7.
-
(2003)
Circulation
, vol.108
, pp. 2195-2197
-
-
Muller, I.1
Besta, F.2
Schulz, C.3
-
27
-
-
0031955060
-
Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease
-
Furman MI, Benoit SE, Barnard MR, et al. Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease. J Am Coll Cardiol 1998; 31: 352-8.
-
(1998)
J. Am. Coll. Cardiol.
, vol.31
, pp. 352-358
-
-
Furman, M.I.1
Benoit, S.E.2
Barnard, M.R.3
-
28
-
-
0348110562
-
Aspirin treatment does not attenuate platelet or leukocyte activation as monitored by whole blood flow cytometry
-
Li N, Hu H, Hjemdahl P. Aspirin treatment does not attenuate platelet or leukocyte activation as monitored by whole blood flow cytometry. Thromb Res 2003; 111: 165-70.
-
(2003)
Thromb. Res.
, vol.111
, pp. 165-170
-
-
Li, N.1
Hu, H.2
Hjemdahl, P.3
-
29
-
-
0036175177
-
Close relationship between the platelet activation marker CD62 and the granular release of platelet-derived growth factor
-
Graff J, Klinkhardt U, Schini-Kerth VB, et al. Close relationship between the platelet activation marker CD62 and the granular release of platelet-derived growth factor. J Pharmacol Exp Ther 2002; 300: 952-7.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.300
, pp. 952-957
-
-
Graff, J.1
Klinkhardt, U.2
Schini-Kerth, V.B.3
-
30
-
-
1042301420
-
Akt activation in platelets depends on Gi signaling pathways
-
Kim S, Jin J, Kunapuli SP. Akt activation in platelets depends on Gi signaling pathways. J Biol Chem 2004; 279: 4186-95.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4186-4195
-
-
Kim, S.1
Jin, J.2
Kunapuli, S.P.3
-
31
-
-
0036198919
-
Effects of combined therapy with clopidogrel and acetyl-salicylic acid on platelet glycoprotein expression and aggregation
-
Dorr G, Schmidt G, Grate M, et al. Effects of combined therapy with clopidogrel and acetyl-salicylic acid on platelet glycoprotein expression and aggregation. J Cardiovasc Pharmacol 2002; 39: 523-32.
-
(2002)
J. Cardiovasc. Pharmacol.
, vol.39
, pp. 523-532
-
-
Dorr, G.1
Schmidt, G.2
Grate, M.3
|