Mitogen-activated protein kinases: Specificity of response to dose of ionizing radiation in liver

Journal of Radiation Research

Volumn 45, Issue 2, 2004, Pages 213-220

  Narang, H ^a   Krishna, M ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Dose response; Irradiation; MAP kinase

Indexed keywords

ENZYME ACTIVITY; IONIZING RADIATION; RADIATION SHIELDING; TRANSCRIPTION; TRANSCRIPTION FACTORS;

CONDITION; CYTOTOXIC; DIVERGENTS; DOSE RESPONSE; IN-VIVO; LOW DOSE; MAP KINASE; MITOGEN-ACTIVATED PROTEIN KINASE; STRESS-ACTIVATED KINASE; TEMPORAL RESPONSE;

CHEMICAL ACTIVATION;

MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 2; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ELK 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOPATHOLOGY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GAMMA RADIATION; HISTOPATHOLOGY; IONIZING RADIATION; LIVER; LIVER INJURY; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; RADIATION DOSE; RADIATION RESPONSE; RAT; UPREGULATION;

ANIMALIA; CERVUS ELAPHUS;

EID: 4544323253     PISSN: 04493060     EISSN: None     Source Type: Journal    
DOI: 10.1269/jrr.45.213     Document Type: Article

References (33)

1. Nishida, E. and Gotoh, Y. (1993) The MAP kinase cascade is essential for diverse signal transduction pathways. Trends. Biochem. Sci. 18: 128-131.
2. Cobb, M. H. and Goldsmith, E. J. (1995) How MAP kinases are regulated. J. Biol. Chem. 270: 14843-14846.
3. Chen, Y. R., Wang, X., Templeton, D., Davis, R. J. and Tan, T. H. (1996) The role of c-Jun N terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation: Duration of jnk activation may determine cell death and proliferation. J. Biol. Chem. 271: 31929-31936.
4. Shafman, T. D., Saleem, A. J., Kyriakis, Weichselbaum, R., Kharbanda, S. and Kufe, D. W. (1995) Defective induction of stress-activated protein kinase activity in ataxia-telangiectasia cells exposed to ionizing radiation. Cancer Res. 55: 3242-3245.
5. Wang, C. Y., Mayo, M. W. and Baldwin, A. S. (1996) TNF and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kB. Science 274: 784-787.
6. Sherman, M. L., Datta, R., Hallahan, D. E., Weichselbaum, R. R. and Kufe, D. W. (1990) Ionizing radiation regulates expression of the c-jun protooncogene. Proc. Natl. Acad. Sci. USA 87: 5663-5666.
7. Hallahan, D. E., Sukhatme, V. P., Sherman, M. L., Virudachalam, S., Kufe, D. and Weichselbaum, R. R. (1991) Protein kinase C mediates X-ray inducibility of nuclear signal transducers EGR1 and JUN. Proc. Natl. Acad. Sci. USA 88: 2156-2160.
8. Datta, R., Rubin, E., Sukhatme, V., Qureshi, S., Hallahan, D., Weichselbaum, R. R. and Kufe, D. (1992) Ionizing radiation activates transcription of the EGR1 gene via CArG elements. Proc. Natl. Acad. Sci. USA 89: 10149-10153.
9. Hallahan, D. E., Gius, D., Kuchibhotla, J., Sukhatme, V., Kufe, D. W. and Weichselbaum, R. R. (1993) Radiation signalling mediated by Jun activation following dissociation from a cell type-specific repressor. J. Biol. Chem. 268: 4903-4907.
10. Hallahan, D. E., Dunphy, E., Virudachalam, S., Sukhatme, V., Kufe, D. W. and Weichselbaum, R. R. (1995) c-jun and Egr-1 participate in DNA synthesis and cell survival in response to ionizing. Radiat. Exposure 270: 30303-30309.
11. Abbott, and Holt, J. T. (1999) Mitogen activated protein kinase 2 activation is essential for progression through the G2/M checkpoint arrest in cells exposed to ionizing radiation. J. Biol. Chem. 5: 2732-2742.
12. Yacoub, A., Park, J. S., Qiao, L., Dent, P. and Hagan, M. P. (2001) MAPK dependence of damage repair: ionizing radiation and the induction of expression of the DNA repair genes XRCC1 and ERCC1 in DU145 human prostate carcinoma cells in a MEK1/2 dependent fashion. Int. J. Radiat. Biol. 77: 1067-1078.
13. Kato, F., Kakihara, H., Kunugita, N., Ootsiyama, A. and Norimura, T. (2002) Role of p53 gene in apoptotic repair of genotoxic tissue damage in mice. J. Radiat. Res. 43, S209-S212.
14. Tombes, R. M., Auer, K. L., Mikkelson, R., Valerie, K., Wymann, M. P., Marshall, C. J., McMahon, M. and Dent, P. (1998) The mitogen activated kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending on whether its activation is acute/phasic or chronic. Biochem. J. 330: 1451-1460.
15. Faris, M., Kokot, N., Latinis, K., Kasibhalta, S., Green, D. R., Koretzky, G. A. and Nel, A. (1998) The c-jun N-terminal kinase cascade plays a role in stress-induced apoptosis in jurkat cells by up-regulating fas ligand expression. J. Immunonol. 160: 134-144.
16. Hama-Inaba, H., Choi, K. H., Wang, B., Haginoya, K., Yamada, T., Hayata, I. and Ohyama, H. (2001) Fas-independent apoptosis induced by UV-C in p53 mutated human epithelial tumor A431 cells through activation of caspases-8 and JNK/SAPK. J. Radiat. Res. 42: 201-215.
17. Deak, M., Clifton, A. D., Lucoco, L. M. and Alessi, D. R. (1998) Mitogen and Stress activated protein kinase-1 (MSK-1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB. EMBO J. 15: 4426-4441.
18. Poon, R. Y. C., Jiang, W., Toyoshima, H. and Hunter, T. (1996) Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Thr-15 phosphorylation after UV-induced DNA damage. J. Biol. Chem. 271: 13283-13291.
19. Daino, K., Ichimura, S. and Nenoi, M. (2002) Early induction of CDKN1A (p21) and GADD45 mRNA by a low dose of ionizing radiation is due to their dose dependent post-transcriptional regulation. Radiat. Res. 157: 478-482.
20. Carter, S., Auer, K. L., Reardon, D. B., Birrer, M., Fisher, P. B., Valerie, K., Schmidt, R. U., Mikkelsen, R. and Dent, P. (1998) Inhibition of Mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose radiation in A431 human squamous carcinoma cells. Oncogene 16: 2787-2796.
21. Mori, K., Tani, M., Kamata, K., Kawamura, H., Urata, Y., Goto, S., Kuwano, M., Shibata, S. and Kondo, T. (2000) Mitogen-activated protein kinase, ERK1/2, is essential for the induction of vascular endothelial growth factor by ionizing radiation mediated by the activator protein-1 in human glioblastoma cells. Free Radic. Res. 33: 157-166.
22. Varadkar, P. A., Krishna, M. and Verma, N. C. (2003) Dose dependent differential expression of protein kinase C (PKC) Isozymes in mice lymphocytes following gamma irradiation in vivo and ex vivo. Radiat. Res. 153: 453-457.
23. Varadkar, P. A. and Krishna, M. (2004) Differential activation of kinases ex vivo and in vivo irradiated mice lymphocytes. J. Radiat. Res., in press
24. Lowry, O. H., Rosebrough, N. S., Farr, A. L. and Randall, R. L. (1951) Protein measurement with pholin phenol reagent. J. Biol. Chem. 193: 265-275.
25. Treisman, R. (1994) Ternary complex factors: growth factors regulated transcriptional activators. Curr. Opin. Genet. Dev. 4: 96-101.
26. Hibi, M., Lin, A., Smeal, T., Minden, A. and Karin, M. (1993) Identification of an oncoprotein-and UV-responsive protein kinase that binds and potentiated the c-Jun activation domain. Genes Dev. 7: 2135-2148.
27. Derijard, B., Hibi, M., Wu, I-H., Barrett, T., Su, B., Deng, T., Karin, M. and Davis, R. J. (1994) JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76: 1025-1037.
28. Kyriakis, J. M., Banerjee, P., Nikolakaki, E., Dai, T., Rubie, E. A., Ahmad, M. F., Avruch, J. and Woodgett, J. R. (1994) The stress activated protein kinase subfamily of c-jun kinases. Nature 369: 156-160.
29. Wada, T., Nakagawa, K., Watanabe, T., Nishita, G., Seo, J., Kishimoto, H., Kitagawa, D., Sasaki, T., Penninger, J. M., Nishina, H. and Katada, T. (2001) Impaired Synergistic activation of Stress-activated protein kinase SAPK/JNK in mouse embryonic stem cells lacking SEK1/MKK4. J. Biol. Chem. 276: 30892-30897.
30. Zinck, R., Hipskind, R. A., Pingoud, V. and Nordheim, A. (1993) c-fos transcriptional activation and repression correlate temporally with the phosphorylation status of TCF. EMBO J. 12: 2377-87.
31. Cavigelli, M., Dolfi, F., Claret, F. and Karin, M. (1995) Induction of c-fos expression through JNK-mediated TCF/Elk-1 Phosphorylation. EMBO J. 14: 5957-5964.
32. Criswell, T., Leskov, K., Miyamoto, S., Luo, G. and Boothman, D. (2003) Transcription factors in mammalian cells after clinically relevant doses of Ionizing radiation. Oncogene 22: 5813-5827.
33. Gille, H., Kortenjann, M., Thomae, O., Moomaw, C., Slaughter, C., Cobb, M. H. and Shaw, P. E. (1995) ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation. EMBO J. 14: 951-962.