Hunting drug targets by systems-level modeling of gene expression profiles

IEEE Transactions on Nanobioscience

Volumn 3, Issue 3, 2004, Pages 180-191

  Dejori, Mathaeus ^a,b   Schuermann, Bernd ^a   Stetter, Martin ^a  

^a SIEMENS AG   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Bayesian network; Gene regulatory networks; Interventional modeling; Oncogenes; Scale free networks

Indexed keywords

CELLS; COMPUTER SIMULATION; DNA; DRUG PRODUCTS; MATHEMATICAL MODELS; PROBLEM SOLVING; PROTEINS; STATISTICAL METHODS; TISSUE; TOPOLOGY;

BAYESIAN NETWORKS; GENE REGULATORY NETWORKS; INTERVENTIONAL MODELING; ONCOGENES; SCALE FREE NETWORKS;

GENETIC ENGINEERING;

PROTEOME; TUMOR MARKER;

ACUTE LYMPHOCYTIC LEUKEMIA; ALGORITHM; ANIMAL; ARTICLE; BAYES THEOREM; BIOLOGICAL MODEL; COMPARATIVE STUDY; COMPUTER SIMULATION; DNA MICROARRAY; DRUG DELIVERY SYSTEM; DRUG DESIGN; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; METHODOLOGY; SIGNAL TRANSDUCTION; STATISTICAL MODEL;

ALGORITHMS; ANIMALS; BAYES THEOREM; COMPUTER SIMULATION; DRUG DELIVERY SYSTEMS; DRUG DESIGN; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE; MODELS, BIOLOGICAL; MODELS, STATISTICAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEOME; SIGNAL TRANSDUCTION; TUMOR MARKERS, BIOLOGICAL;

EID: 4544310280     PISSN: 15361241     EISSN: None     Source Type: Journal    
DOI: 10.1109/TNB.2004.833690     Document Type: Article

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