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Volumn 5, Issue 9, 2004, Pages 1887-1897

Pharmacoeconomics of low-molecular-weight heparins: Limitations of studies comparing them to unfractionated heparin

Author keywords

Heparin; Heparin induced thrombocytopenia; Low molecular weight; Pharmacoeconomics; Unfractionated

Indexed keywords

ANTITHROMBOCYTIC AGENT; ARGATROBAN; DANAPAROID; ENOXAPARIN; FIBRINOGEN RECEPTOR ANTAGONIST; HEPARIN; HIRULOG; LEPIRUDIN; LOW MOLECULAR WEIGHT HEPARIN; PROTAMINE; THROMBIN INHIBITOR; TINZAPARIN; WARFARIN; XIMELAGATRAN;

EID: 4544291027     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.5.9.1887     Document Type: Review
Times cited : (6)

References (37)
  • 1
    • 0036091655 scopus 로고    scopus 로고
    • Review of enoxaparin and its clinical applications in venous and arterial thromboembolism
    • TURPIE AGG, MASON JA: Review of enoxaparin and its clinical applications in venous and arterial thromboembolism. Expert Opin. Pharmacother. (2002) 3(5):575-598.
    • (2002) Expert Opin. Pharmacother. , vol.3 , Issue.5 , pp. 575-598
    • Turpie, A.G.G.1    Mason, J.A.2
  • 2
    • 0035133938 scopus 로고    scopus 로고
    • Prevention of venous thromboembolism
    • GEERTS WH, HEIT JA, CLAGETT GP et al.: Prevention of venous thromboembolism. Chest (2001) 119:132S-175S.
    • (2001) Chest , vol.119
    • Geerts, W.H.1    Heit, J.A.2    Clagett, G.P.3
  • 3
    • 0037383972 scopus 로고    scopus 로고
    • Randomized comparison of enoxaparin with unfractionated heparin for the prevention of venous thromboembolism in medical patients with heart failure or severe respiratory disease
    • KLEBER F-X, WITT C, VOGEL G, KOPPENHAGEN K, SCHOMAKER U, FLOSBACH CW: Randomized comparison of enoxaparin with unfractionated heparin for the prevention of venous thromboembolism in medical patients with heart failure or severe respiratory disease Am. Heart J. (2003) 145:614-621.
    • (2003) Am. Heart J. , vol.145 , pp. 614-621
    • Kleber, F.-X.1    Witt, C.2    Vogel, G.3    Koppenhagen, K.4    Schomaker, U.5    Flosbach, C.W.6
  • 4
    • 0029925784 scopus 로고    scopus 로고
    • Low-molecular-weight heparins and unfractionated heparin in the treatment of patients with acute venous thromboembolism: Results of a meta-analysis
    • SIRAGUSA S, COSMI B, PIOVELLA F, HIRSCH J, GINSBERG JS: Low-molecular-weight heparins and unfractionated heparin in the treatment of patients with acute venous thromboembolism: results of a meta-analysis. Am. J. Med. (1996) 100:269-277.
    • (1996) Am. J. Med. , vol.100 , pp. 269-277
    • Siragusa, S.1    Cosmi, B.2    Piovella, F.3    Hirsch, J.4    Ginsberg, J.S.5
  • 5
    • 0742283969 scopus 로고    scopus 로고
    • Low-molecular-weight heparin compared with intravenous unfractionated heparin for treatment of pulmonary embolism; a meta-analysis of randomised, controlled trials
    • QUINLAN DJ, MCQUILLAN A, EIKELBOOM JW: Low-molecular-weight heparin compared with intravenous unfractionated heparin for treatment of pulmonary embolism; a meta-analysis of randomised, controlled trials. Ann. Intern. Med. (2004) 140:175-183.
    • (2004) Ann. Intern. Med. , vol.140 , pp. 175-183
    • Quinlan, D.J.1    Mcquillan, A.2    Eikelboom, J.W.3
  • 6
    • 8544279582 scopus 로고    scopus 로고
    • A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease
    • COHEN M, DEMERS C, GURFINKEL EP et al.: A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease. N. Engl. J. Med. (1997) 337:447-452.
    • (1997) N. Engl. J. Med. , vol.337 , pp. 447-452
    • Cohen, M.1    Demers, C.2    Gurfinkel, E.P.3
  • 7
    • 0030751133 scopus 로고    scopus 로고
    • Efficacy and safety of enoxaparin versus unfractionated heparin for prevention of deep vein thrombosis in elective cancer surgery: A double-blind, randomized multicentre trial with venographic assessment
    • for the ENOXACAN study group
    • BERGQVIST D, for the ENOXACAN study group: Efficacy and safety of enoxaparin versus unfractionated heparin for prevention of deep vein thrombosis in elective cancer surgery: a double-blind, randomized multicentre trial with venographic assessment Br. J. Surg. (1997) 84:1099-1103.
    • (1997) Br. J. Surg. , vol.84 , pp. 1099-1103
    • Bergqvist, D.1
  • 8
    • 0030448884 scopus 로고    scopus 로고
    • Thromboprophylaxis with low molecular weight heparin after major orthopaedic surgery is cost effective
    • BORRIS LC, RUD LASSEN M: Thromboprophylaxis with low molecular weight heparin after major orthopaedic surgery is cost effective. Drugs (1996) 52(Suppl. 7):42-46.
    • (1996) Drugs , vol.52 , Issue.SUPPL. 7 , pp. 42-46
    • Borris, L.C.1    Rud Lassen, M.2
  • 10
    • 0026567609 scopus 로고
    • Subcutaneous heparin compared with continuous intravenous heparin administration in the initial treatment of deep vein thrombosis
    • HOMMES DW, BURA A, MAZZOLAI L, BULLER HR, TEN CATE JW: Subcutaneous heparin compared with continuous intravenous heparin administration in the initial treatment of deep vein thrombosis. Ann. Intern. Med. (1992) 116:279-284.
    • (1992) Ann. Intern. Med. , vol.116 , pp. 279-284
    • Hommes, D.W.1    Bura, A.2    Mazzolai, L.3    Buller, H.R.4    Ten Cate, J.W.5
  • 11
    • 0022460462 scopus 로고
    • Heparin and the in-hospital management of deep venous thrombosis: Cost considerations
    • ROOKE TW, OSMUNDSON PJ: Heparin and the in-hospital management of deep venous thrombosis: Cost considerations. Mayo Clin. Proc. (1986) 61:198-204.
    • (1986) Mayo Clin. Proc. , vol.61 , pp. 198-204
    • Rooke, T.W.1    Osmundson, P.J.2
  • 12
    • 0032552936 scopus 로고    scopus 로고
    • Cost-effectiveness of low-molecular-weight heparin and unfractionated heparin in treatment of deep vein thrombosis
    • RODGER M, BREDESON C, WELLS PS, BECK J, KEARNS B, HUEBSCH L: Cost-effectiveness of low-molecular-weight heparin and unfractionated heparin in treatment of deep vein thrombosis. Can. Med. Assoc. J. (1998) 159(8):931-938.
    • (1998) Can. Med. Assoc. J. , vol.159 , Issue.8 , pp. 931-938
    • Rodger, M.1    Bredeson, C.2    Wells, P.S.3    Beck, J.4    Kearns, B.5    Huebsch, L.6
  • 13
    • 0032751231 scopus 로고    scopus 로고
    • Economic evaluation of outpatient treatment with low-molecular-weight-heparin for proximal vein thrombosis
    • O'BRIEN B, LEVINE M, WILLAN A et al.: Economic evaluation of outpatient treatment with low-molecular-weight-heparin for proximal vein thrombosis. Arch. Intern. Med. (1999) 159(19):2298-2304.
    • (1999) Arch. Intern. Med. , vol.159 , Issue.19 , pp. 2298-2304
    • O'brien, B.1    Levine, M.2    Willan, A.3
  • 14
    • 0033976126 scopus 로고    scopus 로고
    • Cost-effectiveness of low-molecular-weight heparin in the treatment of proximal deep vein thrombosis
    • ESTRADA CA, MANSFIELD CJ, HEUDEBERT GR: Cost-effectiveness of low-molecular-weight heparin in the treatment of proximal deep vein thrombosis. J. Gen. Intern. Med. (2000) 15(2):108-115.
    • (2000) J. Gen. Intern. Med. , vol.15 , Issue.2 , pp. 108-115
    • Estrada, C.A.1    Mansfield, C.J.2    Heudebert, G.R.3
  • 15
    • 0036965514 scopus 로고    scopus 로고
    • Cost comparison of at-home treatment of deep venous thrombosis with low molecular weight heparin to inpatient treatment with unfractionated heparin. Intern
    • SMITH BJ, WEEKLEY JS, PILOTTO L, HOWE T, BEVEN R: Cost comparison of at-home treatment of deep venous thrombosis with low molecular weight heparin to inpatient treatment with unfractionated heparin. Intern. Med. J. (2002) 32:29-34.
    • (2002) Med. J. , vol.32 , pp. 29-34
    • Smith, B.J.1    Weekley, J.S.2    Pilotto, L.3    Howe, T.4    Beven, R.5
  • 16
    • 0032925807 scopus 로고    scopus 로고
    • Low-molecular-weight heparins compared with unfractionated heparin for treatment of acute deep venous thrombosis: A cost-effectiveness analysis
    • GOULD MK, DEMBITZER AD, SANDERS GD, GARBER AM: Low-molecular-weight heparins compared with unfractionated heparin for treatment of acute deep venous thrombosis: a cost-effectiveness analysis. Ann. Intern. Med. (1999) 130:789-799.
    • (1999) Ann. Intern. Med. , vol.130 , pp. 789-799
    • Gould, M.K.1    Dembitzer, A.D.2    Sanders, G.D.3    Garber, A.M.4
  • 17
    • 0027445078 scopus 로고
    • Efficacy and cost of low-molecular-weight heparin compared with standard heparin for the prevention of deep vein thrombosis after total hip arthroplasty
    • ANDERSON DR, O'BRIEN BJ, LEVINE MN, ROBERTS R, WELLS PS, HIRSCH J: Efficacy and cost of low-molecular-weight heparin compared with standard heparin for the prevention of deep vein thrombosis after total hip arthroplasty. Ann. Intern. Med. (1993) 119(11):1105-1112.
    • (1993) Ann. Intern. Med. , vol.119 , Issue.11 , pp. 1105-1112
    • Anderson, D.R.1    O'brien, B.J.2    Levine, M.N.3    Roberts, R.4    Wells, P.S.5    Hirsch, J.6
  • 18
    • 0027455778 scopus 로고
    • Low molecular weight versus standard heparin for prevention of venous thromboembolism after major abdominal surgery
    • KAKKAR VV, COHEN AT, EDMONSON RA et al.: Low molecular weight versus standard heparin for prevention of venous thromboembolism after major abdominal surgery. Lancet (1993) 341:259-265.
    • (1993) Lancet , vol.341 , pp. 259-265
    • Kakkar, V.V.1    Cohen, A.T.2    Edmonson, R.A.3
  • 19
    • 3042782723 scopus 로고    scopus 로고
    • Enoxaparin versus unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndromes managed with an intended early invasive strategy
    • SYNERGY TRIAL INVESTIGATORS
    • SYNERGY TRIAL INVESTIGATORS: Enoxaparin versus unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndromes managed with an intended early invasive strategy. JAMA (2004) 292:45-54.
    • (2004) JAMA , vol.292 , pp. 45-54
  • 20
    • 0026576068 scopus 로고
    • Subcutaneous low-molecular-weight heparin compared with intravenous heparin in the treatment of proximal vein thrombosis
    • HULL RD RASKOB GE, PINEO GF et al.: Subcutaneous low-molecular-weight heparin compared with intravenous heparin in the treatment of proximal vein thrombosis. N. Engl. J. Med. (1992) 326:975-982.
    • (1992) N. Engl. J. Med. , vol.326 , pp. 975-982
    • Hull, R.D.1    Raskob, G.E.2    Pineo, G.F.3
  • 21
    • 8044255251 scopus 로고    scopus 로고
    • Treatment of proximal vein thrombosis with subcutaneous low-molecular-weight heparin versus intravenous heparin: An economic perspective
    • HULL RD, RASKOB GE, ROSENBLOOM D et al.: Treatment of proximal vein thrombosis with subcutaneous low-molecular-weight heparin versus intravenous heparin: an economic perspective. Arch. Intern. Med. (1997) 157(3):289-294.
    • (1997) Arch. Intern. Med. , vol.157 , Issue.3 , pp. 289-294
    • Hull, R.D.1    Raskob, G.E.2    Rosenbloom, D.3
  • 22
    • 0038347146 scopus 로고    scopus 로고
    • Pharmacotherapy of heparin-induced thrombocytopenia
    • DAGER WE, WHITE RH: Pharmacotherapy of heparin-induced thrombocytopenia. Expert Opin. Pharmacother. (2003) 4(6):919-940.
    • (2003) Expert Opin. Pharmacother. , vol.4 , Issue.6 , pp. 919-940
    • Dager, W.E.1    White, R.H.2
  • 23
    • 0037610515 scopus 로고    scopus 로고
    • An improved definition of immune heparin-induced thrombocytopaenia in postoperative orthopaedic patients
    • WARKENTIN TE, ROBERTS RS, HIRSCH J, KELTON JG: An improved definition of immune heparin-induced thrombocytopaenia in postoperative orthopaedic patients. Arch. Intern. Med. (2003) 163:2518-2524.
    • (2003) Arch. Intern. Med. , vol.163 , pp. 2518-2524
    • Warkentin, T.E.1    Roberts, R.S.2    Hirsch, J.3    Kelton, J.G.4
  • 24
    • 0030281338 scopus 로고    scopus 로고
    • A 14-year study of heparin-induced thrombocycopenia
    • WARKENTIN TE, KELTON JG: A 14-year study of heparin-induced thrombocycopenia. Am. J. Med. (1996) 101:502-507.
    • (1996) Am. J. Med. , vol.101 , pp. 502-507
    • Warkentin, T.E.1    Kelton, J.G.2
  • 25
    • 0036733708 scopus 로고    scopus 로고
    • Venous limb gangrene during overlapping therapy with warfarin and a direct thrombin inhibitor for immune heparin-induced thrombocytopenia
    • SMYTHE MA, WARKENTIN TE, STEPHENS JL, ZAKALIK D, MATTSON JC: Venous limb gangrene during overlapping therapy with warfarin and a direct thrombin inhibitor for immune heparin-induced thrombocytopenia. Am. J. Haematol. (2002) 71:50-52.
    • (2002) Am. J. Haematol. , vol.71 , pp. 50-52
    • Smythe, M.A.1    Warkentin, T.E.2    Stephens, J.L.3    Zakalik, D.4    Mattson, J.C.5
  • 26
    • 0035853125 scopus 로고    scopus 로고
    • Recombinant hirudin in clinical practice. Focus on lepirudin
    • GREINACHER A, LUBENOW N: Recombinant hirudin in clinical practice. Focus on lepirudin. Circulation (2001) 103:1479-1484.
    • (2001) Circulation , vol.103 , pp. 1479-1484
    • Greinacher, A.1    Lubenow, N.2
  • 27
    • 0035953702 scopus 로고    scopus 로고
    • Temporal aspects of heparin-induced thrombocytopenia
    • WARKENTIN TE, KELTON JG: Temporal aspects of heparin-induced thrombocytopenia. N. Engl. J. Med. (2001) 344:1286-1292.
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1286-1292
    • Warkentin, T.E.1    Kelton, J.G.2
  • 28
    • 0036881566 scopus 로고    scopus 로고
    • Platelet count monitoring and laboratory testing for heparin-induced thrombocyropenia: Recommendations for the College of American Pathologists
    • WARKENTIN TE: Platelet count monitoring and laboratory testing for heparin-induced thrombocyropenia: recommendations for the College of American Pathologists. Arch. Pathol. Lab. Med. (2002) 126:1415-1423.
    • (2002) Arch. Pathol. Lab. Med. , vol.126 , pp. 1415-1423
    • Warkentin, T.E.1
  • 29
    • 17544388644 scopus 로고    scopus 로고
    • Subcutaneous low-molecular-weight heparin versus warfarin for prophylaxis of deep vein thrombosis after hip or knee implantation: An economic perspective
    • HULL RD, RASKOB GE, PINEO GF et al.: Subcutaneous low-molecular-weight heparin versus warfarin for prophylaxis of deep vein thrombosis after hip or knee implantation: an economic perspective. Arch. Intern. Med. (1997) 157(3):298-303.
    • (1997) Arch. Intern. Med. , vol.157 , Issue.3 , pp. 298-303
    • Hull, R.D.1    Raskob, G.E.2    Pineo, G.F.3
  • 30
    • 0034015081 scopus 로고    scopus 로고
    • Will the use of low-molecular-weight heparin (enoxaparin) in patients with acute coronary syndrome save costs in Canada?
    • O'BRIEN BJ, WILLAN A, BLACKHOUSE G, GOEREE R, COHEN M, GOODMAN S: Will the use of low-molecular-weight heparin (enoxaparin) in patients with acute coronary syndrome save costs in Canada? Am. Heart. J (2000) 139(3):423-429.
    • (2000) Am. Heart J , vol.139 , Issue.3 , pp. 423-429
    • O'brien, B.J.1    Willan, A.2    Blackhouse, G.3    Goeree, R.4    Cohen, M.5    Goodman, S.6
  • 31
    • 0141498170 scopus 로고    scopus 로고
    • Unresolved issues in anticoagulant therapy
    • SCHULMAN S: Unresolved issues in anticoagulant therapy. J. Thromb. Haemostasis (2003) 1:1464-1470.
    • (2003) J. Thromb. Haemostasis , vol.1 , pp. 1464-1470
    • Schulman, S.1
  • 32
    • 0036738186 scopus 로고    scopus 로고
    • The pharmacokinetics and pharmacodynamics of enoxaparin in obese volunteers
    • SANDERINK G-J, LIBOUX AL, JARIWALA N et al.: The pharmacokinetics and pharmacodynamics of enoxaparin in obese volunteers. Clin. Pharmacol. Ther. (2002) 72:308-318.
    • (2002) Clin. Pharmacol. Ther. , vol.72 , pp. 308-318
    • Sanderink, G.-J.1    Liboux, A.L.2    Jariwala, N.3
  • 33
    • 0037485598 scopus 로고    scopus 로고
    • Safety and efficacy of unfractionated heparin versus enoxaparin in patients who are obese and patients with sever renal impairment: Analysis from the ESSENCE and TIMI 11B studies
    • SPINLER SA, INVERSO SM, COHEN M, GOODMAN SG, STRINGER KA, ANTMAN EM: Safety and efficacy of unfractionated heparin versus enoxaparin in patients who are obese and patients with sever renal impairment: analysis from the ESSENCE and TIMI 11B studies. Am. Heart. J. (2003) 146:33-41.
    • (2003) Am. Heart J. , vol.146 , pp. 33-41
    • Spinler, S.A.1    Inverso, S.M.2    Cohen, M.3    Goodman, S.G.4    Stringer, K.A.5    Antman, E.M.6
  • 34
    • 0036474098 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of the prophylactic dose of enoxaparin once daily over 4 days in patients with renal impairment
    • SANDERINK GJCM, GUIMART CG, OZOUX ML, JARIWALA NU, SHUKLA UA, BOUTOUYRIE BX: Pharmacokinetics and pharmacodynamics of the prophylactic dose of enoxaparin once daily over 4 days in patients with renal impairment. Thromb. Res. (2002) 105:225-231.
    • (2002) Thromb. Res. , vol.105 , pp. 225-231
    • Sanderink, G.J.C.M.1    Guimart, C.G.2    Ozoux, M.L.3    Jariwala, N.U.4    Shukla, U.A.5    Boutouyrie, B.X.6
  • 35
    • 0036272018 scopus 로고    scopus 로고
    • Influence of patient characteristics and renal function on Factor Xa inhibition pharmacokinetics and pharmacodynamics after enoxaparin administration in non-ST-segment elevation acute coronary syndromes
    • BECKER RC, SPENCER FA, GIBSON M et al.: Influence of patient characteristics and renal function on Factor Xa inhibition pharmacokinetics and pharmacodynamics after enoxaparin administration in non-ST-segment elevation acute coronary syndromes. Am. Heart J. (2002) 143:753-759.
    • (2002) Am. Heart J. , vol.143 , pp. 753-759
    • Becker, R.C.1    Spencer, F.A.2    Gibson, M.3
  • 36
    • 1542706468 scopus 로고    scopus 로고
    • Thromboprophylaxis practice patterns in hip fracture surgery patients: Experience in Perth, Western Australia
    • WAN S, TING J, OLSEN A, CROSER J, EIKELBOOM JW: Thromboprophylaxis practice patterns in hip fracture surgery patients: experience in Perth, Western Australia. ANZ J. Surg. (2003) 73:826-829.
    • (2003) ANZ J. Surg. , vol.73 , pp. 826-829
    • Wan, S.1    Ting, J.2    Olsen, A.3    Croser, J.4    Eikelboom, J.W.5
  • 37
    • 1642512328 scopus 로고    scopus 로고
    • Audit of surgeon awareness of readmissions with thrombo-embolism
    • SWAN J, SPIGELMAN AD: Audit of surgeon awareness of readmissions with thrombo-embolism. Intern. Med. J. (2003) 33:578-580.
    • (2003) Intern. Med. J. , vol.33 , pp. 578-580
    • Swan, J.1    Spigelman, A.D.2


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