Biologic, morphologic, and molecular characterisation of Neospora caninum isolates from littermate dogs

International Journal for Parasitology

Volumn 34, Issue 10, 2004, Pages 1157-1167

  Dubey, J P ^a   Sreekumar, C ^a   Knickman, E ^b   Miska, K B ^a   Vianna, M C B ^a   Kwok, O C H ^a   Hill, D E ^a   Jenkins, M C ^a   Lindsay, D S ^c   Greene, C E ^d  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b Madonna Veterinary Clinic   (United States)

^c VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

^d UNIVERSITY OF GEORGIA   (United States)

Author keywords

Bradyzoites; Cell culture; Gerbils; Isolation; Mice; Neospora caninum; Neosporosis; Schizogony; Sequence analysis; Ultrastructure

Indexed keywords

GENETIC ANALYSIS; PARASITOLOGY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CAT; CELL CULTURE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DOG; GERBIL; INOCULATION; MOUSE; NEOSPORA CANINUM; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE DEVELOPMENT; PARASITE IDENTIFICATION; PARASITE ISOLATION; PARASITE VIRULENCE; POLYMERASE CHAIN REACTION; RODENT; SCHIZONT; SEQUENCE ANALYSIS; SKELETAL MUSCLE; SPECIES DIFFERENCE;

ANIMALS; BASE SEQUENCE; BIOLOGICAL ASSAY; BRAIN; CATS; COCCIDIOSIS; DOG DISEASES; DOGS; GENES, PROTOZOAN; GERBILLINAE; LIFE CYCLE STAGES; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR SEQUENCE DATA; NEOSPORA; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SPECIES SPECIFICITY;

CANIS FAMILIARIS; FELIS CATUS; GERBILLINAE; NEOSPORA CANINUM; RODENTIA;

EID: 4544265336     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpara.2004.07.005     Document Type: Article

References (40)

1. B.C. Barr, P.A. Conrad, J.P. Dubey, and M.L. Anderson Neospora-like encephalomyelitis in a calf: pathology, ultrastructure, and immunoreactivity J. Vet. Diagn. Invest. 3 1991 39 46
2. W. Basso, L. Venturini, M.C. Venturini, D.E. Hill, O.C.H. Kwok, S.K. Shen, and J.P. Dubey First isolation of Neospora caninum from the feces of a naturally infected dog J. Parasitol. 87 2001 612 618
3. I. Bjerks, and J.P. Dubey Evidence that Neospora caninum is identical to the Toxoplasma-like parasite of Norwegian dogs Acta Vet. Scand. 32 1991 407 410
4. I. Bjerks, and J. Presthus Immuno-histochemical and ultrastructural characteristics of a cyst-forming sporozoon associated with encephalomyelitis and myositis in dogs Acta Pathol. Microbiol. Immunol. Scand. 96 1988 445 454
5. J.P. Dubey Duration of immunity to shedding of Toxoplasma gondii oocysts by cats J. Parasitol. 81 1995 410 415
6. J.P. Dubey, F.L. Metzger, A.L. Hattel, D.S. Lindsay, and D.L. Fritz Canine cutaneous neosporosis: clinical improvement with clindamycin Vet. Dermatol. 6 1995 37 43
7. J.P. Dubey Refinement of pepsin digestion method for isolation of Toxoplasma gondii from infected tissues Vet. Parasitol. 74 1998 75 77
8. J.P. Dubey Oocyst shedding by cats fed isolated bradyzoites and comparison of infectivity of bradyzoites of the VEG strain Toxoplasma gondii to cats and mice J. Parasitol. 87 2001 215 219
9. J.P. Dubey Review of Neospora caninum and neosporosis in animals Korean J. Parasitol. 41 2003 1 16
10. J.P. Dubey, and G. Desmonts Serological responses of equids fed Toxoplasma gondii oocysts Equine Vet. J. 19 1987 337 339
11. J.P. Dubey, and D.S. Lindsay A review of Neospora caninum and neosporosis Vet. Parasitol. 67 1996 1 59
12. J.P. Dubey, and C. Sreekumar Redescription of Hammondia hammondi and its differentiation from Toxoplasma gondii Int. J. Parasitol. 33 2003 1437 1453
13. J.P. Dubey, A.L. Hattel, D.S. Lindsay, and M.J. Topper Neonatal Neospora caninum infection in dogs: isolation of the causative agent and experimental transmission J. Am. Vet. Med. Assoc. 193 1988 1259 1263
14. J.P. Dubey, D.S. Lindsay, and T.P. Lipscomb Neosporosis in cats Vet. Pathol. 27 1990 335 339
15. J.P. Dubey, K.R. Dorough, M.C. Jenkins, S. Liddell, C.A. Speer, O.C.H. Kwok, and S.K. Shen Canine neosporosis: clinical signs, diagnosis, treatment and isolation of Neospora caninum in mice and cell culture Int. J. Parasitol. 28 1998 1293 1304
16. J.P. Dubey, M.M. Garner, M.D. Stetter, A.E. Marsh, and B.C. Barr Acute Sarcocystis falcatula-like infection in a carmine bee-eater (Merops nubicus) and immunohistochemical cross reactivity between Sarcocystis falcatula and Sarcocystis neurona J. Parasitol. 87 2001 824 831
17. J.P. Dubey, B.C. Barr, J.R. Barta, I. Bjerks, C. Björkman, B.L. Blagburn, D.D. Bowman, D. Buxton, J.T. Ellis, B. Gottstein, A. Hemphill, D.E. Hill, D.K. Howe, M.C. Jenkins, Y. Kobayashi, B. Koudela, A.E. Marsh, J.G. Mattsson, M.M. McAllister, D. Modrý, Y. Omata, L.D. Sibley, C.A. Speer, A.J. Trees, A. Uggla, S.J. Upton, D.J.L. Williams, and D.S. Lindsay Redescription of Neospora caninum and its differentiation from related coccidia Int. J. Parasitol. 32 2002 929 946
18. L.F.P. Gondim, L. Gao, and M.M. McAllister Improved production of Neospora caninum oocysts, cyclical transmission between dogs and cattle, and in vitro isolation from oocysts J. Parasitol. 88 2002 1159 1163
19. L.F.P. Gondim, M.M. McAllister, W.C. Pitt, and D.E. Zemlicka Coyotes (Canis latrans) are definitive hosts of Neospora caninum Int. J. Parasitol. 34 2004 159 161
20. L.F.P. Gondim, P. Laski, L. Gao, and M.M. McAllister Variation of the internal transcribed spacer 1 sequence within individual strains and among different strains of Neospora caninum J. Parasitol. 90 2004 119 122
21. J.E. Jardine The ultrastructure of bradyzoites and tissue cysts of Neospora caninum in dogs: absence of distinguishing morphological features between parasites of canine and bovine origin Vet. Parasitol. 62 1996 231 240
22. D.S. Lindsay, and J.P. Dubey Immunohistochemical diagnosis of Neospora caninum in tissue sections Am. J. Vet. Res. 50 1989 1981 1983
23. D.S. Lindsay, and J.P. Dubey Neospora caninum (Protozoa: Apicomplexa) infections in mice J. Parasitol. 75 1989 772 779
24. D.S. Lindsay, B.L. Blagburn, and J.P. Dubey Factors affecting the survival of Neospora caninum bradyzoites in murine tissues J. Parasitol. 78 1992 70 72
25. D.S. Lindsay, J.P. Dubey, and R.B. Duncun Confirmation that the dog is a definitive host for Neospora caninum Vet. Parasitol. 82 1999 327 333
26. M.M. McAllister, A.M. McGuire, W.R. Jolley, D.S. Lindsay, A.J. Trees, and R.H. Stobart Experimental neosporosis in pregnant ewes and their offspring Vet. Parasitol. 33 1996 647 655
27. M.M. McAllister, S.F. Parmley, L.M. Weiss, V.J. Welch, and A.M. McGuire An immunohistochemical method for detecting bradyzoite antigen (BAG5) in Toxoplasma gondii-infected tissues cross-reacts with a Neospora caninum bradyzoite antigen J. Parasitol. 82 1996 354 355
28. M.M. McAllister, J.P. Dubey, D.S. Lindsay, W.R. Jolley, R.A. Wills, and A.M. McGuire Dogs are definitive hosts of Neospora caninum Int. J. Parasitol. 28 1998 1473 1478
29. M.M. McAllister, W.R. Jolley, R.A. Wills, D.S. Lindsay, A.M. McGuire, and J.D. Tran's Oral inoculation of cats with tissue cysts of Neospora caninum Am. J. Vet. Res. 59 1998 441 444
30. J.W. McGarry, C.M. Stockton, D.J.L. Williams, and A.J. Trees Protracted shedding of oocysts of Neospora caninum by a naturally infected foxhound J. Parasitol. 89 2003 628 630
31. A.M. McGuire, M.M. McAllister, and W.R. Jolley Separation and cryopreservation of Neospora caninum tissue cysts from murine brain J. Parasitol. 83 1997 319 321
32. M. Peters, F. Wagner, and G. Schares Canine neosporosis: clinical and pathological findings and first isolation of Neospora caninum in Germany Parasitol. Res. 86 2000 1 7
33. M. Peters, E. Lütkefels, A.R. Heckeroth, and G. Schares Immunohistochemical and ultrastructural evidence for Neospora caninum tissue cysts in skeletal muscles of naturally infected dogs and cattle Int. J. Parasitol. 31 2001 1144 1148
34. S. Romand, P. Thulliez, and J.P. Dubey Direct agglutination test for serologic diagnosis of Neospora caninum infection Parasitol. Res. 84 1998 50 53
35. L.D. Sibley, and J.C. Boothroyd Virulent strains of Toxoplasma gondii comprise a single clonal lineage Nature 39 1992 82 85
36. A. Schock, E.A. Innes, I. Yamane, S.M. Latham, and J.M. Wastling Genetic and biological diversity among isolates of Neospora caninum Parasitology 123 2001 13 23
37. J.R. lapeta, B. Koudela, J. Votypka, D. Modry, R. Horejs, and J. Lukes Coprodiagnosis of Hammondia heydorni in dogs by PCR based amplification of ITS 1 rRNA: differentiation from morphologically indistinguishable oocysts of Neospora caninum Vet. J. 163 2002 147 154
38. C.A. Speer, J.P. Dubey, M.M. McAllister, and J.A. Blixt Comparative ultrastructure of tachyzoites, bradyzoites, and tissue cysts of Neospora caninum and Toxoplasma gondii Int. J. Parasitol. 29 1999 1509 1519
39. C. Sreekumar, D.E. Hill, V.M. Fournet, B.M. Rosenthal, D.S. Lindsay, and J.P. Dubey Detection of Hammondia heydorni-like organisms and their differentiation from Neospora caninum using random-amplified polymorphic DNA-polymerase chain reaction J. Parasitol. 89 2003 1082 1085
40. M. Yamage, O. Flechtner, and B. Gottstein Neospora caninum: specific oligonucleotide primers for the detection of brain 'cyst' DNA of experimentally-infected nude mice by the polymerase chain reaction (PCR) J. Parasitol. 82 1996 272 279