-
1
-
-
0034062124
-
Trends in the incidence of hip fracture in Japan, 1987-1997: The third nationwide survey
-
Orimo H, Hashimoto T, Sakata K, Yoshimura N, Suzuki T, Hosoi T (2000) Trends in the incidence of hip fracture in Japan, 1987-1997: the third nationwide survey. J Bone Miner Metab 18:126-131
-
(2000)
J Bone Miner Metab
, vol.18
, pp. 126-131
-
-
Orimo, H.1
Hashimoto, T.2
Sakata, K.3
Yoshimura, N.4
Suzuki, T.5
Hosoi, T.6
-
2
-
-
0004895060
-
Life time risk of osteoporosis-related bone fractures in a Japanese cohort
-
Fujiwara S, Kasagi F, Kodama K (1997) Life time risk of osteoporosis-related bone fractures in a Japanese cohort. Osteoporosis Int 7 (suppl 2):16
-
(1997)
Osteoporosis Int
, vol.7
, Issue.SUPPL. 2
, pp. 16
-
-
Fujiwara, S.1
Kasagi, F.2
Kodama, K.3
-
3
-
-
0026320852
-
Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure
-
Sato M, Grasser W, Endo N, Akins R, Simmons H, Thompson DD, Golub E, Rodan GA (1991) Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure. J Clin Invest 88:2095-2105
-
(1991)
J Clin Invest
, vol.88
, pp. 2095-2105
-
-
Sato, M.1
Grasser, W.2
Endo, N.3
Akins, R.4
Simmons, H.5
Thompson, D.D.6
Golub, E.7
Rodan, G.A.8
-
4
-
-
0029164610
-
Alendronate distributed on bone surfaces inhibits osteoclastic bone resorption in vitro and in experimental hypercalcemia models
-
Azuma Y, Sato H, Oue Y, Okabe K, Ohta T, Tsuchimoto M, Kiyoki M (1995) Alendronate distributed on bone surfaces inhibits osteoclastic bone resorption in vitro and in experimental hypercalcemia models. Bone (NY) 16:235-245
-
(1995)
Bone (NY)
, vol.16
, pp. 235-245
-
-
Azuma, Y.1
Sato, H.2
Oue, Y.3
Okabe, K.4
Ohta, T.5
Tsuchimoto, M.6
Kiyoki, M.7
-
5
-
-
0028851590
-
Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis
-
Liberman UA, Weiss SR, Broll J, Minne HW, Quan H, Bell NH, Rodriguez-Portales J, Downs RW Jr, Dequeker J, Favus M, Seeman E, Recker RR, Capizzi T, Santora AC II, Lombardi A, Shah RV, Hirsch LJ, Karpf DB (1995) Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. N Engl J Med 333:1437-1443
-
(1995)
N Engl J Med
, vol.333
, pp. 1437-1443
-
-
Liberman, U.A.1
Weiss, S.R.2
Broll, J.3
Minne, H.W.4
Quan, H.5
Bell, N.H.6
Rodriguez-Portales, J.7
Downs Jr., R.W.8
Dequeker, J.9
Favus, M.10
Seeman, E.11
Recker, R.R.12
Capizzi, T.13
Santora II, A.C.14
Lombardi, A.15
Shah, R.V.16
Hirsch, L.J.17
Karpf, D.B.18
-
6
-
-
0030278360
-
Effect of three years of oral alendronate treatment in postmenopausal women with osteoporosis
-
Tucci JR, Tonino RP, Emkey RD, Peverly CA, Kher U, Santora AC II (1996) Effect of three years of oral alendronate treatment in postmenopausal women with osteoporosis. Am J Med 101:488-501
-
(1996)
Am J Med
, vol.101
, pp. 488-501
-
-
Tucci, J.R.1
Tonino, R.P.2
Emkey, R.D.3
Peverly, C.A.4
Kher, U.5
Santora II, A.C.6
-
7
-
-
9044249713
-
Oral alendronate induces progressive increases in bone mass of the spine, hip, and total body over 3 years in postmenopausal women with osteoporosis
-
Devogelaer JP, Broll H, Correa-Rotter R, Cumming DC, Nagant de Deuxchaisnes C, et al. (1996) Oral alendronate induces progressive increases in bone mass of the spine, hip, and total body over 3 years in postmenopausal women with osteoporosis. Bone (NY) 18:141-150
-
(1996)
Bone (NY)
, vol.18
, pp. 141-150
-
-
Devogelaer, J.P.1
Broll, H.2
Correa-Rotter, R.3
Cumming, D.C.4
Nagant De Deuxchaisnes, C.5
-
8
-
-
0004851872
-
Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures
-
Black DM, Cummings SR, Karpf DB, Cauley JA, Thompson DE, Nevitt MC, Bauer DC, Genant HK, Haskell WL, Marcus R, Ott SM, Torner JC, Quandt SA, Reiss TF, Ensrud KE (1996) Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Lancet 348:1535-1541
-
(1996)
Lancet
, vol.348
, pp. 1535-1541
-
-
Black, D.M.1
Cummings, S.R.2
Karpf, D.B.3
Cauley, J.A.4
Thompson, D.E.5
Nevitt, M.C.6
Bauer, D.C.7
Genant, H.K.8
Haskell, W.L.9
Marcus, R.10
Ott, S.M.11
Torner, J.C.12
Quandt, S.A.13
Reiss, T.F.14
Ensrud, K.E.15
-
9
-
-
0031006598
-
Prevention of nonvertebral fractures by alendronate. A meta-analysis
-
Karpf DB, Shapiro DR, Seeman E, Ensrud KE, Johnston CC Jr, Adami S, Harris ST, Santora AC II, Hirsch LJ, Oppenheimer L, Thompson D (1997) Prevention of nonvertebral fractures by alendronate. A meta-analysis. JAMA 277:1159-1164
-
(1997)
JAMA
, vol.277
, pp. 1159-1164
-
-
Karpf, D.B.1
Shapiro, D.R.2
Seeman, E.3
Ensrud, K.E.4
Johnston Jr., C.C.5
Adami, S.6
Harris, S.T.7
Santora II, A.C.8
Hirsch, L.J.9
Oppenheimer, L.10
Thompson, D.11
-
10
-
-
0032583492
-
Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: Results from the fracture intervention trial
-
Cummings SR, Black DM, Thompson DE, Applegate WB, Barrett-Connor E, Musliner TA, Palermo L, Prineas R, Rubin SM, Scott JC, Vogt T, Wallace R, Yates AJ, LaCroix AZ (1998) Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the fracture intervention trial. JAMA 280:2077-2082
-
(1998)
JAMA
, vol.280
, pp. 2077-2082
-
-
Cummings, S.R.1
Black, D.M.2
Thompson, D.E.3
Applegate, W.B.4
Barrett-Connor, E.5
Musliner, T.A.6
Palermo, L.7
Prineas, R.8
Rubin, S.M.9
Scott, J.C.10
Vogt, T.11
Wallace, R.12
Yates, A.J.13
LaCroix, A.Z.14
-
11
-
-
0034983101
-
Alendronate: An update of its use in osteoporosis
-
Sharpe M, Noble S, Spencer CM (2001) Alendronate: an update of its use in osteoporosis. Drugs 61:999-1039
-
(2001)
Drugs
, vol.61
, pp. 999-1039
-
-
Sharpe, M.1
Noble, S.2
Spencer, C.M.3
-
12
-
-
0036677983
-
Meta-analysis of alendronate for the treatment of postmenopausal women
-
Cranney A, Wells G, Willan A, Griffith L, Zytaruk N, Robinson V, Black D, Adachi J, Shea B, Tugwell P, Guyatt G (2002) II. Meta-analysis of alendronate for the treatment of postmenopausal women. Endocr Rev 23:508-516
-
(2002)
Endocr Rev
, vol.23
, pp. 508-516
-
-
Cranney, A.1
Wells, G.2
Willan, A.3
Griffith, L.4
Zytaruk, N.5
Robinson, V.6
Black, D.7
Adachi, J.8
Shea, B.9
Tugwell, P.10
Guyatt II, G.11
-
13
-
-
0033678399
-
Skeletal benefits of alendronate: 7-Year treatment of postmenopausal osteoporotic women
-
Phase III Osteoporosis Treatment Study Group
-
Tonino RP, Meunier PJ, Emkey R, Rodriguez-Portales JA, Menkes CJ, Wasnich RD, Bone HG, Santora AC, Wu M, Desai R, Ross PD (2000) Skeletal benefits of alendronate: 7-year treatment of postmenopausal osteoporotic women. Phase III Osteoporosis Treatment Study Group. J Clin Endocrinol Metab 85:3109-3115
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 3109-3115
-
-
Tonino, R.P.1
Meunier, P.J.2
Emkey, R.3
Rodriguez-Portales, J.A.4
Menkes, C.J.5
Wasnich, R.D.6
Bone, H.G.7
Santora, A.C.8
Wu, M.9
Desai, R.10
Ross, P.D.11
-
14
-
-
0000594779
-
Ten-year efficacy and safety of alendronate in the treatment of osteoporosis in postmenopausal women
-
Emkey R, Reid I, Mulloy AL, Correa-Rotter R, Favus M, Bone H, Gupta J, LaMotta A, Santora AC (2002) Ten-year efficacy and safety of alendronate in the treatment of osteoporosis in postmenopausal women. J Bone Miner Res 17 (suppl 1): S139
-
(2002)
J Bone Miner Res
, vol.17
, Issue.SUPPL. 1
-
-
Emkey, R.1
Reid, I.2
Mulloy, A.L.3
Correa-Rotter, R.4
Favus, M.5
Bone, H.6
Gupta, J.7
LaMotta, A.8
Santora, A.C.9
-
15
-
-
0036747512
-
The efficacy of alendronate in reducing the risk for vertebral fracture in Japanese patients with osteoporosis: A randomized, double-blind, active-controlled, double-dummy trial
-
Kushida K, Shiraki M, Nakamura T, Kishimoto H, Morii H, Yamamoto K, Kaneda K, Fukunaga M, Inoue T, Nakashima M, Orimo H (2002) The efficacy of alendronate in reducing the risk for vertebral fracture in Japanese patients with osteoporosis: a randomized, double-blind, active-controlled, double-dummy trial. Curr Ther Res 63:606-620
-
(2002)
Curr Ther Res
, vol.63
, pp. 606-620
-
-
Kushida, K.1
Shiraki, M.2
Nakamura, T.3
Kishimoto, H.4
Morii, H.5
Yamamoto, K.6
Kaneda, K.7
Fukunaga, M.8
Inoue, T.9
Nakashima, M.10
Orimo, H.11
-
16
-
-
0033065233
-
Bisphosphonates: From the laboratory to the clinic and back again
-
Russell RGG, Rogers MJ (1999) Bisphosphonates: from the laboratory to the clinic and back again. Bone (NY) 25:97-106
-
(1999)
Bone (NY)
, vol.25
, pp. 97-106
-
-
Russell, R.G.G.1
Rogers, M.J.2
-
17
-
-
0033675269
-
Bisphosphonates: Mechanisms of action in multiple myeloma
-
Shipman CM, Rogers MJ, Vanderkerken K, Camp BV, Graham R, Russell G, Croucher PI (2000) Bisphosphonates: mechanisms of action in multiple myeloma. Acta Oncol 39:829-835
-
(2000)
Acta Oncol
, vol.39
, pp. 829-835
-
-
Shipman, C.M.1
Rogers, M.J.2
Vanderkerken, K.3
Camp, B.V.4
Graham, R.5
Russell, G.6
Croucher, P.I.7
-
18
-
-
0033958778
-
Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase
-
Bergstrom JD, Bostedor RG, Masarachia PJ, Reszka AA, Rodan G (2000) Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase. Arch Biochem Biophys 373:231-241
-
(2000)
Arch Biochem Biophys
, vol.373
, pp. 231-241
-
-
Bergstrom, J.D.1
Bostedor, R.G.2
Masarachia, P.J.3
Reszka, A.A.4
Rodan, G.5
-
19
-
-
0026318521
-
Bisphosphonates: Pharmacology and use in the treatment of tumour-induced hypercalcaemic and metastatic bone disease
-
Fleisch H (1991) Bisphosphonates: pharmacology and use in the treatment of tumour-induced hypercalcaemic and metastatic bone disease. Drugs 42:919-944
-
(1991)
Drugs
, vol.42
, pp. 919-944
-
-
Fleisch, H.1
-
20
-
-
0028586042
-
Comparison of new biochemical markers of bone turnover in late postmenopausal osteoporotic women in response to alendronate treatment
-
Garnero P, Shih WJ, Gineyts E, Karpf DB, Delmas PD (1994) Comparison of new biochemical markers of bone turnover in late postmenopausal osteoporotic women in response to alendronate treatment. J Clin Endocrinol Metab 79:1693-1700
-
(1994)
J Clin Endocrinol Metab
, vol.79
, pp. 1693-1700
-
-
Garnero, P.1
Shih, W.J.2
Gineyts, E.3
Karpf, D.B.4
Delmas, P.D.5
-
21
-
-
0027279616
-
Continuous alendronate treatment throughout growth, maturation, and aging in the rat results in increases in bone mass and mechanical properties
-
Guy JA, Shea M, Peter CP, Morrissey R, Hayes WC (1993) Continuous alendronate treatment throughout growth, maturation, and aging in the rat results in increases in bone mass and mechanical properties. Calcif Tissue Int 53:283-288
-
(1993)
Calcif Tissue Int
, vol.53
, pp. 283-288
-
-
Guy, J.A.1
Shea, M.2
Peter, C.P.3
Morrissey, R.4
Hayes, W.C.5
-
22
-
-
0027139913
-
The effects of 2-year treatment with the aminobisphosphonate alendronate on bone metabolism, bone histomorphometry, and bone strength in ovariectomized nonhuman primates
-
Balena R, Toolan BC, Shea M, Markatos A, Myers ER, Lee SC, Opas EE, Seedor JG, Klein H, Frankenfield D, Quartuccio H, Fioravanti C, Clair J, Brown E, Hayes WC, Rodan GA (1993) The effects of 2-year treatment with the aminobisphosphonate alendronate on bone metabolism, bone histomorphometry, and bone strength in ovariectomized nonhuman primates. J Clin Invest 92:2577-2586
-
(1993)
J Clin Invest
, vol.92
, pp. 2577-2586
-
-
Balena, R.1
Toolan, B.C.2
Shea, M.3
Markatos, A.4
Myers, E.R.5
Lee, S.C.6
Opas, E.E.7
Seedor, J.G.8
Klein, H.9
Frankenfield, D.10
Quartuccio, H.11
Fioravanti, C.12
Clair, J.13
Brown, E.14
Hayes, W.C.15
Rodan, G.A.16
-
23
-
-
0030868816
-
Histomorphometric assessment of the long-term effects of alendronate on bone quality and remodeling in patients with osteoporosis
-
Chavassieux PM, Arlot ME, Reda C, Wei L, Yates AJ, Meunier PJ (1997) Histomorphometric assessment of the long-term effects of alendronate on bone quality and remodeling in patients with osteoporosis. J Clin Invest 100:1475-1480
-
(1997)
J Clin Invest
, vol.100
, pp. 1475-1480
-
-
Chavassieux, P.M.1
Arlot, M.E.2
Reda, C.3
Wei, L.4
Yates, A.J.5
Meunier, P.J.6
-
24
-
-
0033755981
-
Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women
-
Boivin GY, Chavassieux PM, Santora AC, Yates J, Meunier PJ (2000) Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women. Bone (NY) 27:687-694
-
(2000)
Bone (NY)
, vol.27
, pp. 687-694
-
-
Boivin, G.Y.1
Chavassieux, P.M.2
Santora, A.C.3
Yates, J.4
Meunier, P.J.5
-
25
-
-
0035701682
-
Changes in bone remodeling rate influence the degree of mineralization of bone which is a determinant of bone strength: Therapeutic implications
-
Boivin G, Meunier PJ (2001) Changes in bone remodeling rate influence the degree of mineralization of bone which is a determinant of bone strength: therapeutic implications. Adv Exp Med Biol 496:123-127
-
(2001)
Adv Exp Med Biol
, vol.496
, pp. 123-127
-
-
Boivin, G.1
Meunier, P.J.2
-
26
-
-
7144251176
-
A placebo-controlled, single-blind study to determine the appropriate alendronate dosage in postmenopausal Japanese patients with osteoporosis
-
Shiraki M, Kushida K, Fukunaga M, Kishimoto H, Kaneda K, Minaguchi H, Inoue T, Tomita A, Nagata Y, Nakashima M, Orimo H (1998) A placebo-controlled, single-blind study to determine the appropriate alendronate dosage in postmenopausal Japanese patients with osteoporosis. Endocr J 45:191-201
-
(1998)
Endocr J
, vol.45
, pp. 191-201
-
-
Shiraki, M.1
Kushida, K.2
Fukunaga, M.3
Kishimoto, H.4
Kaneda, K.5
Minaguchi, H.6
Inoue, T.7
Tomita, A.8
Nagata, Y.9
Nakashima, M.10
Orimo, H.11
-
27
-
-
20444506156
-
A double-blind, dose-ranging study of alendronate in patients with involutional osteoporosis, osteoporotic osteopenia or artificial menopause
-
Nakamura T, Kushida K, Shiraki M, Fukunaga M, Taga M, Kishimoto H, Tomita A, Inoue T, Minaguchi H, Kaneda K, Nagata Y, Nakashima M, Orimo H (1998) A double-blind, dose-ranging study of alendronate in patients with involutional osteoporosis, osteoporotic osteopenia or artificial menopause (in Japanese). Med Consul New Remedy 35:3-17
-
(1998)
Med Consul New Remedy
, vol.35
, pp. 3-17
-
-
Nakamura, T.1
Kushida, K.2
Shiraki, M.3
Fukunaga, M.4
Taga, M.5
Kishimoto, H.6
Tomita, A.7
Inoue, T.8
Minaguchi, H.9
Kaneda, K.10
Nagata, Y.11
Nakashima, M.12
Orimo, H.13
-
28
-
-
4544388061
-
A long-term study of alendronate in patients with involutional osteoporosis
-
Kishimoto H, Shiraki M, Fukunaga M, Kushida K, Kaneda K, Inoue T, Tomita A, Yamamoto K, Orimo H (1998) A long-term study of alendronate in patients with involutional osteoporosis (in Japanese). Med Consul New Remedy 35:19-41
-
(1998)
Med Consul New Remedy
, vol.35
, pp. 19-41
-
-
Kishimoto, H.1
Shiraki, M.2
Fukunaga, M.3
Kushida, K.4
Kaneda, K.5
Inoue, T.6
Tomita, A.7
Yamamoto, K.8
Orimo, H.9
-
29
-
-
6544276586
-
A double-masked multicenter comparative study between alendronate and alfacalcidol in Japanese patients with osteoporosis
-
Shiraki M, Kushida K, Fukunaga M, Kishimoto H, Taga M, Nakamura T, Kaneda K, Minaguchi H, Inoue T, Morii H, Tomita A, Yamamoto K, Nagata Y, Nakashima M, Orimo H (1999) A double-masked multicenter comparative study between alendronate and alfacalcidol in Japanese patients with osteoporosis. Osteoporos Int 10:183-192
-
(1999)
Osteoporos Int
, vol.10
, pp. 183-192
-
-
Shiraki, M.1
Kushida, K.2
Fukunaga, M.3
Kishimoto, H.4
Taga, M.5
Nakamura, T.6
Kaneda, K.7
Minaguchi, H.8
Inoue, T.9
Morii, H.10
Tomita, A.11
Yamamoto, K.12
Nagata, Y.13
Nakashima, M.14
Orimo, H.15
-
30
-
-
0010496839
-
Esophagitis associated with the use of alendronate
-
de Groen PC, Lubbe DF, Hirsch LJ, Daifotis A, Stephenson W, Freedholm D, Pryor-Tillotson S, Seleznick MJ, Pinkas H, Wang KK (1996) Esophagitis associated with the use of alendronate. N Engl J Med 335:1016-1021
-
(1996)
N Engl J Med
, vol.335
, pp. 1016-1021
-
-
De Groen, P.C.1
Lubbe, D.F.2
Hirsch, L.J.3
Daifotis, A.4
Stephenson, W.5
Freedholm, D.6
Pryor-Tillotson, S.7
Seleznick, M.J.8
Pinkas, H.9
Wang, K.K.10
-
31
-
-
0031671019
-
Esophageal irritation due to alendronate sodium tablets: Possible mechanisms
-
Peter CP, Handt LK, Smith SM (1998) Esophageal irritation due to alendronate sodium tablets: possible mechanisms. Dig Dis Sci 43:1998-2002
-
(1998)
Dig Dis Sci
, vol.43
, pp. 1998-2002
-
-
Peter, C.P.1
Handt, L.K.2
Smith, S.M.3
-
32
-
-
0036789682
-
Oral bisphosphonates and upper gastrointestinal tract problems: What is the evidence?
-
Cryer B, Bauer DC (2002) Oral bisphosphonates and upper gastrointestinal tract problems: what is the evidence? Mayo Clin Proc 77:1031-1043
-
(2002)
Mayo Clin Proc
, vol.77
, pp. 1031-1043
-
-
Cryer, B.1
Bauer, D.C.2
-
33
-
-
0034723772
-
Upper gastrointestinal tract safety profile of alendronate: The fracture intervention trial
-
Bauer DC, Black D, Ensrud K, Thompson D, Hochberg M, Nevitt M, Musliner T, Freedholm D (2000) Upper gastrointestinal tract safety profile of alendronate: the fracture intervention trial. Arch Intern Med 160:517-525
-
(2000)
Arch Intern Med
, vol.160
, pp. 517-525
-
-
Bauer, D.C.1
Black, D.2
Ensrud, K.3
Thompson, D.4
Hochberg, M.5
Nevitt, M.6
Musliner, T.7
Freedholm, D.8
-
34
-
-
0034536509
-
Rechallenge of patients who had discontinued alendronate therapy because of upper gastrointestinal symptoms
-
Miller PD, Woodson G, Licata AA, Ettinger MP, Mako B, Smith ME, Wang L, Yates J, Melton ME, Palmisano JJ (2000) Rechallenge of patients who had discontinued alendronate therapy because of upper gastrointestinal symptoms. Clin Ther 22:1433-1442
-
(2000)
Clin Ther
, vol.22
, pp. 1433-1442
-
-
Miller, P.D.1
Woodson, G.2
Licata, A.A.3
Ettinger, M.P.4
Mako, B.5
Smith, M.E.6
Wang, L.7
Yates, J.8
Melton, M.E.9
Palmisano, J.J.10
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