A Facile Sodium Alkoxide Mediated Ring Opening of Unactivated α-dienyl-βlactams: Synthesis of Unnatural Multicomponent β-aminodienoic Esters

Heterocycles

Volumn 73, Issue C, 2007, Pages 689-698

  Anand, Amit ^a   Bhargava, Gaurav ^a   Hundal, Maninder Singh ^a   Mahajan, Mohinder P ^a  

^a GURU NANAK DEV UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 45349108512     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/COM-07-S(U)48     Document Type: Article

References (23)

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4. In: Juaristi E. (Ed). Enantioselective Synthesis of β -Amino Acids. (1997), Wiley-VCH, New York Chapter 1
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21. The starting materials α-dienyl-β-lactams are trans with N-aryl substituents and cis with N-alkyl substituents.
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23. -l, T = 298(2) K, λ=0.71073 Å, Final R indices [I_ 2.0σ(I)] R1=.0602, wR2 = 0.1548, R indices (all data) [I_ 2.0σ(I)] R1 = 0.1037, wR2 = 0.1904 (3412 collections), GOF = 1.068 (311 parameters). Diffraction data were measured on a Bruker APEX CCD-Detector X-ray diffractometer. Structure solution, refinements were carried out with Shelx-97.