Pregnancy-associated plasma protein A and proform eosinophilic major basic protein in the detection of different types of coronary artery disease

Physiological Research

Volumn 57, Issue 1, 2008, Pages 23-32

  Hájek, Petr ^a,c   Macek, M ^a   Hladikova M ^a   Houbova B ^a   Alan, D ^a   Durdil, V ^a   Fiedler, J ^a   Maly M ^a   Ostadal P ^a   Veselka, J ^a   Krebsova A ^b  

^a CHARLES UNIVERSITY   (Czech Republic)

^b HUMBOLDT UNIVERSITY   (Germany)

^c UNIVERSITY HOSPITAL MOTOL   (Czech Republic)

Author keywords

Atherosclerosis; Cardiac troponin I; Coronary artery disease; PAPP A proMBP

Indexed keywords

BIOLOGICAL MARKER; DIAGNOSTIC AGENT; MAJOR BASIC PROTEIN; PREGNANCY ASSOCIATED PLASMA PROTEIN A; PROTEIN PRECURSOR; TROPONIN I;

ACUTE CORONARY SYNDROME; ADULT; AGE; AGED; ARTICLE; BLOOD; CASE CONTROL STUDY; CLASSIFICATION; COHORT ANALYSIS; CORONARY ARTERY DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IMMUNOASSAY; INSTRUMENTATION; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; NONPARAMETRIC TEST; RECEIVER OPERATING CHARACTERISTIC; REFERENCE VALUE; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SEX DIFFERENCE; VALIDATION STUDY;

ACUTE CORONARY SYNDROME; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; COHORT STUDIES; CORONARY ARTERY DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; EOSINOPHIL MAJOR BASIC PROTEIN; FEMALE; HUMANS; IMMUNOASSAY; MALE; MIDDLE AGED; PREGNANCY-ASSOCIATED PLASMA PROTEIN-A; PROTEIN PRECURSORS; REFERENCE VALUES; RISK ASSESSMENT; ROC CURVE; SENSITIVITY AND SPECIFICITY; SEX FACTORS; STATISTICS, NONPARAMETRIC; TROPONIN I;

EID: 45349087743     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. APPLE FS, WU AHB, MAIR J, RAVKILDE J, PANTEGHINI M, TATE J, PAGANI F, CHRISTENSON RH, MOCKEL M, DANNE O, JAFFE S, on behalf of the Committee of Standardization of Markers of Cardiac Damage of the IFCC: Future biomarkers for detection of ischemia and risk stratification in acute coronary syndrome. Clin Chem 51: 810-824, 2005.
2. ASO Y, OKUMURA K, WAKABAYASHI S, TAKEBAYASHI K, TAKI S, INUKAI T: Elevated pregnancy-associated plasma protein-A in sera from type 2 diabetic patients with hypercholesterolemia: associations with carotid atherosclerosis and toe-brachial index. J Clin Endocrinol Metab 89: 5713-5717, 2004.
3. BAYES-GENIS A, CONOVER CA, SCHWARTZ RS: The insulin-like growth factor axis. A review of atherosclerosis and restenosis. Circ Res 86: 125-130, 2000.
4. BAYES-GENIS A, CONOVER CA, OVERGAARD MT, BAILEY KR, CHRISTIANSEN M, HOLMES DR Jr, VIRMANI R, OXVIG C, SCHWARTZ RS: Pregnancy-associated plasma protein A as a marker of acute coronary syndromes. N Engl J Med 345: 1022-1029, 2001a.
5. BAYES-GENIS A, SCHWARTZ RS, LEWIS DA, OVERGAARD MT, CHRISTIANSEN M, OXVIG C, ASHAI K, HOLMES DR JR, CONOVER CA: Insulin-like growth factor binding protein-4 protease produced by smooth muscle cells increases in the coronary artery after angioplasty. Arterioscler Thromb Vasc Biol 21: 335-341, 2001b.
6. BEAUDEUX JL, BURC L, IMBERT-BISMUT F, GIRAL P, BERNARD M, BRUCKERT E, CHAPMAN MJ: Serum plasma pregnancy-associated protein A: a potential marker of echogenic carotid atherosclerotic plaques in asymptomatic hyperlipidemic subjects at high cardiovascular risk. Arterioscler Thromb Vasc Biol 23: e7-e10, 2003.
7. BONNO M, OXVIG C, KEPHART GM, WAGNER JM, KRISTENSEN T, SOTTRUP-JENSEN L, GLEICH GJ: Localization of pregnancy-associated plasma protein-A and colocalization of pregnancy-associated plasma protein-A messenger ribonucleic acid and eosinophil granule major basic protein messenger ribonucleic acid in placenta. Lab Invest 71: 560-566, 1994.
8. CHE W, LERNER-MARMAROSH N, HUANG Q, OSAWA M, OHTA S, YOSHIZUMI M, GLASSMAN M, LEE JD, YAN C, BERK BC, ABE J: Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: role of Gab1 and MEKK3 in TNF-alpha-induced c-Jun and NF-kappaB activation and adhesion molecule expression. Circ Res 90: 1222-1230, 2002.
9. CHEN BK, LEIFERMAN KM, PITTELKOW MR., OVERGAARD MT, OXVIG C, CONOVER CA: Localization and regulation of pregnancy-associated plasma protein A expression in healing human skin. J Clin Endocrinol Metab 88: 4465-4471, 2003.
10. CHRISTIANSEN M, JALIASHVILI I, OVERGAARD MT, ENSINGER C, OBRIST P, OXVIG C: Quantification and characterization of pregnancy-associated complexes of angiotensinogen and the proform of eosinophil major basic protein in serum and amniotic fluid. Clin Chem 46: 1099-1105, 2000.
11. COSIN-SALES J, CHRISTIANSEN M, KAMINSKI P, OXVIG C, OVERGAARD MT, COLE D, HOLT DW, KASKI JC: Pregnancy-associated plasma protein-A a and its endogenous inhibitor, the proform of eosinophil major basic protein (proMBP), are related to complex stenosis morphology in patients with stable angina pectoris. Circulation 109: 1724-1728, 2004.
12. COSIN-SALES J, KASKI JC, CHRISTIANSEN M, KAMINSKI P, OXVIG C, OVERGAARD MT, COLE D, HOLT DW: Relationship among pregnancy associated plasma protein-A levels, clinical characteristics, and coronary artery disease extent in patients with chronic stable angina pectoris. Eur Heart J 26: 2093-2098, 2005.
13. DOMINGUEZ-RODRIGUEZ A, ABREU-GONZALEZ P, GARCIA-GONZALEZ M, FERRER J, VARGAS M: Circulating pregnancy-associated plasma protein A is not an early marker of acute myocardial infarction. Clin Biochem 38: 180-182, 2005.
14. FARB A, BURKE AP, TANG AL, LIANG TY, MANNAN P, SMIALEK J, VIRMANI R: Coronary plaque erosion without rupture into a lipid core. A frequent cause of coronary thrombosis in sudden coronary death. Circulation 93: 1354-1363, 1996.
15. GLERUP S, BOLDT HB, OVERGAARD MT, SOTTRUP-JENSEN L, GIUDICE LC, OXVIG C: Proteinase inhibition by proform of eosinophil major basic protein (pro-MBP) is a multistep process of intra- and intermuscular disulfide rearrangements. J Biol Chem 280: 9823-9832, 2005.
16. HEESCHEN C, DIMMELER S, HAMM CW, FICHTLSCHERER S, SIMOONS ML, ZEIHER AM, CAPTURE Study Investigators: Pregnancy-associated plasma protein-A levels in patients with acute coronary syndromes: comparison with markers of systemic inflammation, platelet activation, and myocardial necrosis. J Am Coll Cardiol 45: 229-237, 2005.
17. JADLOWIEC J, DONGELL D, SMITH J, CONOVER C, CAMPBELL P: PAPP-A is involved in matrix mineralization of human adult mesenchymal stem cells and angiogenesis in the chick CAM. Endocrinology 146: 3765-3772, 2005.
18. KALOUSOVÁ M, HOŘEJŠÍ M, FIALOVÁ L, SOUKUPOVÁ J, SULKOVÁ S, MALBOHAN I, TESAŘ I, ZIMA T: Increased levels of pregnancy-associated plasma protein A are associated with mortality in hemodialysis patients: preliminary results. Blood Purif 22: 298-300, 2004.
19. KHOSRAVI J, DIAMANDI A, KRISHNA RG, BODANI U, MISTRY J, KHAJA N: Pregnancy associated plasma protein-A: ultrasensitive immunoassay and determination in coronary heart disease. Clin Biochem 35: 531-538, 2002.
20. LATERZA OF, CAMERON SJ, CHAPPELL D, SOKOLL LJ, GREEN GB: Evaluation of pregnancy-associated plasma protein A as a prognostic indicator in acute coronary syndrome patients. Clin Chim Acta 348: 163-169, 2004.
21. LAURSEN LS, OVERGAARD MT, SOE R, BOLDT HB, SOTTRUP-JENSEN L, GIUDICE LC, CONOVER CA, OXVIG C: Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: Implications for the mechanism of IGFBP-4 proteolysis by PAPP-A. FEBS Lett 504: 36-40, 2001.
22. LAWRENCE JB, OXVIG C, OVERGAARD MT, SOTTRUP-JENSEN L, GLEICH GJ, HAYS LG, YATES JR 3rd, CONOVER CA: The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A. Proc Natl Acad Sci USA 96: 3149-3153, 1999.
23. LUND J, QIN Q-P, ILVA T, PETTERSSON K, VOIPIO-PULKKI LM, PORELA P, PULKKI K: Circulating pregnancy-associated plasma protein-A predicts outcome in patients with acute coronary syndrome but no troponin I elevation. Circulation 108: 1924-1926, 2003.
24. OXVIG C, SAND O, KRISTENSEN T, GLEICH GJ, SOTTRUP-JENSEN L: Circulating human pregnancy-associated plasma protein-A is disulfide-bridged to the proform of eosinophil major basic protein. J Biol Chem 268: 12243-12246, 1993.
25. OXVIG C, HAANING J, KRISTENSEN L, WAGNER JM, RUBIN I, STIGBRAND T, GLEICH GJ, SOTTRUPJENSEN L: Identification of angiotensinogen and complement C3dg as novel proteins binding the proform of eosinophil major basic protein in human pregnancy serum and plasma. J Biol Chem 270: 13645-13651, 1995.
26. OVERGAARD MT, OXVIG C, CHRISTIANSEN M, LAWRENCE JB, CONOVER CA, GLEICH GJ, SOTTRUPJENSEN L, HAANING J: Messenger ribonucleic acid levels of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein: expression in human reproductive and nonreproductive tissues. Biol Reprod 61: 1083-1089, 1999.
27. OVERGAARD MT, HAANNING J, BOLDT HB, OLSEN IM, LAURSEN LS, CHRISTIANSEN M, GLEICH GJ, SOTTRUP-JENSEN L, CONOVER CA, OXVIG C: Expression of recombinant human pregnancy-associated plasma protein-A and identification of the proform of eosinophil major basic protein as its physiological inhibitor. J Biol Chem 275: 31128-31133, 2000.
28. QIN Q-P, LAITINEN P, MAJAMAA-VOLTTI K, ERIKSSON S, KUMPULA E-K, PETTERSSON K: Release patterns of pregnancy associated plasma protein A (PAPP-A) in patients with acute coronary syndromes. Scand Cardiovasc J 36: 358-361, 2002.
29. QIN Q-P, KOKKALA S, LUND J, TAMM N, VOIPIO-PULKKI L-M, PETTERSSON K: Molecular distinction of circulating pregnancy-associated plasma protein A in myocardial infarction and pregnancy. Clin Chem 51: 75-83, 2005.
30. QIN Q-P, KOKKALA S, LUND J, TAMM N, QIN X, LEPANTALO M, PETTERSSON K: Immunoassays developed for pregnancy-associated plasma protein-A (PAPP-A) in pregnancy may not recognize PAPP-A in acute coronary syndromes. Clin Chem 52: 398-404, 2006.
31. RAUCH AE, AMYOT KM, DUNN HG, NG B, WILNER G: Hypereosinophilic syndrome and myocardial infarction in a 15-year-old. Pediatr Pathol Lab Med 17: 469-486, 1997.
32. RESCH ZT, CHEN BK, BALE LK, OXVIG C, OVERGAARD MT, CONOVER CA: Pregnancy-associated plasma protein a gene expression as a target of inflammatory cytokines. Endocrinology 145: 1124-1129, 2004.
33. SLUNGAARD A, VERCELLOTTI GM, TRAN T, GLEICH GJ, KEY NS: Eosinophil cationic granule proteins impair thrombomodulin function. A potential mechanism for thromboembolism in hypereosinophilic heart disease. J Clin Invest 91: 1721-1730, 1993.
34. SPENCER K: The influence of different sample collection types on the levels of markers used for Down's syndrome screening as measured by the Kryptor immunoassay system. Ann Clin Biochem 40: 166-168, 2003.
35. ŠTULC T, MALBOHAN I, MALÍK J, FIALOVÁ L, SOUKUPOVÁ J, ČEŠKA R: Increased levels of pregnancy-associated plasma protein-A in patients with hypercholesterolemia: the effect of atorvastatin treatment. Am Heart J 146: 1060-1063, 2003.
36. SWETS JA: Measuring the accuracy of diagnostic systems. Science 240: 1285-1293, 1988.
37. TAI PC, ACKERMAN SJ, SPRY CJ, DUNNETTE S, OLSEN EG, GLEICH GJ: Deposits of eosinophil granule proteins in cardiac tissues of patients with eosinophilic endomyocardial disease. Lancet 1: 643-647, 1987.