Drug delivery to the colon using a novel one-step dry-coated tablets (OSDrC)

Yakugaku Zasshi

Volumn 128, Issue 6, 2008, Pages 951-957

  Sakurai, Masato ^a   Ozeki, Yuichi ^b   Ando, Masaki ^b   Okamoto, Hirokazu ^a   Danjo, Kazumi ^a  

^a MEIJO UNIVERSITY   (Japan)

^b SANWA KAGAKU KENKYUSHO CO LTD   (Japan)

Author keywords

Bile acid; Chitosan; Colon targeting; Colonic fluid; Gastric acid; One step dry coated tablet(OSDrC)

Indexed keywords

CHITOSAN; EUDRAGIT; FLUOROURACIL; GASTROINTESTINAL AGENT; ONE STEP DRY COATED TABLET; PHOSPHATE BUFFERED SALINE;

ACIDITY; ARTICLE; COLON; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG TARGETING; INTESTINE TRANSIT TIME; SIMULATION; SMALL INTESTINE; STOMACH; STOMACH ACID; STOMACH EMPTYING; STOMACH JUICE; TABLET FORMULATION;

BILE ACIDS AND SALTS; CHITOSAN; COLON; DRUG DELIVERY SYSTEMS; GASTRIC ACID; GASTRIC EMPTYING; GASTROINTESTINAL TRACT; HYDROGEN-ION CONCENTRATION; POLYMETHACRYLIC ACIDS; SOLUBILITY; TABLETS, ENTERIC-COATED; TECHNOLOGY, PHARMACEUTICAL; TIME FACTORS;

EID: 45249103325     PISSN: 00316903     EISSN: 13475231     Source Type: Journal    
DOI: 10.1248/yakushi.128.951     Document Type: Article

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