The association of osteoprotegerin gene polymorphisms with periodontitis

Oral Diseases

Volumn 14, Issue 5, 2008, Pages 440-444

  Park, O J ^a   Shin, S Y ^a   Choi, Y ^a   Kim, M H ^a   Chung, C P ^a   Ku, Y ^a   Kim, K K ^a,b  

^a Seoul National University   (South Korea)

^b School of Dentistry   (South Korea)

Author keywords

Osteoprotegerin; Periodontitis; Polymorphism; Risk factor

Indexed keywords

ADULT; ALLELE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE MUTATION; HUMAN; MALE; OSTEOPROTEGERIN GENE; PERIODONTITIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE STRAND CONFORMATION POLYMORPHISM;

ADULT; CASE-CONTROL STUDIES; CHRONIC DISEASE; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; OSTEOPROTEGERIN; PERIODONTITIS; POLYMORPHISM, GENETIC; REFERENCE VALUES; SEVERITY OF ILLNESS INDEX;

EID: 45249098468     PISSN: 1354523X     EISSN: 16010825     Source Type: Journal    
DOI: 10.1111/j.1601-0825.2007.01398.x     Document Type: Article

References (24)

1. Arko B, Prezelj J, Komel R, Kocijancic A, Hudler P, Marc J (2002). Sequence variations in the osteoprotegerin gene promoter in patients with postmenopausal osteoporosis. J Clin Endocrinol Metab 87 : 4080 4084.
2. Brandstrom H, Bjorkman T, Ljunggren O (2001). Regulation of osteoprotegerin secretion from primary cultures of human bone marrow stromal cells. Biochem Biophys Res Commun 280 : 831 835.
3. Brandstrom H, Stiger F, Lind L, Kahan T, Melhus H, Kindmark A (2002). A single nucleotide polymorphism in the promoter region of the human gene for osteoprotegerin is related to vascular morphology and function. Biochem Biophys Res Commun 293 : 13 17.
4. Brandstrom H, Gerdhem P, Stiger F et al (2004). Single nucleotide polymorphisms in the human gene for osteoprotegerin are not related to bone mineral density or fracture in elderly women. Calcif Tissue Int 74 : 18 24.
5. Bucay N, Sarosi I, Dunstan CR. et al (1998). Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification. Genes Dev 12 : 1260 1268.
6. Choi JY, Shin A, Park SK et al (2005). Genetic polymorphisms of OPG, RANK, and ESR1 and bone mineral density in Korean postmenopausal women. Calcif Tissue Int. 77 : 152 159.
7. Daroszewska A, Hocking LJ, McGuigan FE et al (2004). Susceptibility to Paget's disease of bone is influenced by a common polymorphic variant of osteoprotegerin. J Bone Miner Res 19 : 1506 1511.
8. Kinane DF, Shiba H, Hart TC (2005). The genetic basis of periodontitis. Periodontol 2000 39 : 91 117.
9. Langdahl BL, Carstens M, Stenkjaer L, Eriksen EF (2002). Polymorphisms in the osteoprotegerin gene are associated with osteoporotic fractures. J Bone Miner Res 17 : 1245 1255.
10. Michalowicz BS, Diehl SR, Gunsolley JC et al (2000). Evidence of a substantial genetic basis for risk of adult periodontitis. J Periodontol 71 : 1699 1707.
11. Mogi M, Otogoto J, Ota N, Togari A (2004). Differential expression of RANKL and osteoprotegerin in gingival crevicular fluid of patients with periodontitis. J Dent Res 83 : 166 169.
12. Ohmori H, Makita Y, Funamizu M et al (2002). Linkage and association analyses of the osteoprotegerin gene locus with human osteoporosis. J Hum Genet 47 : 400 406.
13. Reddy MS (2002). Oral osteoporosis: is there an association between periodontitis and osteoporosis? Compend Contin Educ Dent 23 : 21 28.
14. Roux S, Orcel P (2000). Bone loss. Factors that regulate osteoclast differentiation: an update. Arthritis Res 2 : 451 456.
15. Soufi M, Schoppet M, Sattler AM et al (2004). Osteoprotegerin gene polymorphisms in men with coronary artery disease. J Clin Endocrinol Metab 89 : 3764 3768.
16. Suda T, Takahashi N, Udagawa N, Jimi E, Gillespie MT, Martin TJ (1999). Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev. 20 : 345 357.
17. Tezal M, Wactawski-Wende J, Grossi SG, Ho AW, Dunford R, Genco RJ (2000). The relationship between bone mineral density and periodontitis in postmenopausal women. J Periodontol 71 : 1492 1498.
18. Vidal C, Brincat M, Xuereb Anastasi A (2006). TNFRSF11B gene variants and bone mineral density in postmenopausal women in Malta. Maturitas 53 : 386 395.
19. Wactawski-Wende J (2001). Periodontal diseases and osteoporosis: association and mechanisms. Ann Periodontol 6 : 197 208.
20. Wada N, Maeda H, Tanabe K et al (2001). Periodontal ligament cells secrete the factor that inhibits osteoclastic differentiation and function: the factor is osteoprotegerin/osteoclastogenesis inhibitory factor. J Periodontal Res 36 : 56 63.
21. Wohlfahrt JC, Wu T, Hodges JS, Hinrichs JE, Michalowicz BS (2006). No association between selected candidate gene polymorphisms and severe chronic periodontitis. J Periodontol 77 : 426 436.
22. Wynne F, Drummond F, O'Sullivan K et al (2002). Investigation of the genetic influence of the OPG, VDR (Fok1), and COLIA1 Sp1 polymorphisms on BMD in the Irish population. Calcif Tissue Int 71 : 26 35.
23. Yamada Y, Ando F, Niino N, Shimokata H (2003). Association of polymorphisms of the osteoprotegerin gene with bone mineral density in Japanese women but not men. Mol Genet Metab 80 : 344 349.
24. Zhao HY, Liu JM, Ning G et al (2005). The influence of Lys3Asn polymorphism in the osteoprotegerin gene on bone mineral density in Chinese postmenopausal women. Osteoporos Int 16 : 1519 1524.