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Volumn 371, Issue 9630, 2008, Pages 2059-2060

Laquinimod, a new oral drug for multiple sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; BETA1A INTERFERON; GADOLINIUM; GLATIRAMER; INTERFERON BETA SERINE; LAQUINIMOD; MITOXANTRONE; NATALIZUMAB; PLACEBO; ROQUINIMEX;

EID: 45249089662     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(08)60894-6     Document Type: Note
Times cited : (6)

References (17)
  • 2
    • 45249107267 scopus 로고    scopus 로고
    • Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study
    • for the LAQ/5062 Study Group
    • Comi G., Pulizzi A., Rovaris M., et al., for the LAQ/5062 Study Group. Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study. Lancet 371 (2008) 2085-2092
    • (2008) Lancet , vol.371 , pp. 2085-2092
    • Comi, G.1    Pulizzi, A.2    Rovaris, M.3
  • 3
    • 15244353263 scopus 로고    scopus 로고
    • Treatment with laquinimod reduces development of active MRI lesions in relapsing MS
    • Polman C., Barkhof F., Sandberg-Wollheim M., et al. Treatment with laquinimod reduces development of active MRI lesions in relapsing MS. Neurology 64 (2005) 987-991
    • (2005) Neurology , vol.64 , pp. 987-991
    • Polman, C.1    Barkhof, F.2    Sandberg-Wollheim, M.3
  • 4
    • 0031545950 scopus 로고    scopus 로고
    • Single-dose gadolinium with magnetization transfer versus triple-dose gadolinium in the MR detection of multiple sclerosis lesions
    • van Waesberghe J., Castelijns J., Roser W., et al. Single-dose gadolinium with magnetization transfer versus triple-dose gadolinium in the MR detection of multiple sclerosis lesions. AJNR Am J Neuroradiol 18 (1997) 1279-1285
    • (1997) AJNR Am J Neuroradiol , vol.18 , pp. 1279-1285
    • van Waesberghe, J.1    Castelijns, J.2    Roser, W.3
  • 5
    • 0021035886 scopus 로고
    • Rating neurological impairment in multiple sclerosis: an expanded disability status scale (EDSS)
    • Kurtzke J. Rating neurological impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 33 (1983) 1444-1452
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.1
  • 6
    • 0032919071 scopus 로고    scopus 로고
    • Development of a multiple sclerosis functional composite as a clinical trial outcome measure
    • Cutter G., Baier M., Rudick R., et al. Development of a multiple sclerosis functional composite as a clinical trial outcome measure. Brain 122 (1999) 871-882
    • (1999) Brain , vol.122 , pp. 871-882
    • Cutter, G.1    Baier, M.2    Rudick, R.3
  • 7
    • 0036070623 scopus 로고    scopus 로고
    • MRI monitoring of MS in clinical trials
    • Miller D. MRI monitoring of MS in clinical trials. Clin Neurol Neurosurg 104 (2002) 236-243
    • (2002) Clin Neurol Neurosurg , vol.104 , pp. 236-243
    • Miller, D.1
  • 8
    • 0031844371 scopus 로고    scopus 로고
    • Histopathologic correlate of hypointense lesions on T1-weighted spin-echo MRI in multiple sclerosis
    • van Walderveen M., Kamphorst W., Scheltens P., et al. Histopathologic correlate of hypointense lesions on T1-weighted spin-echo MRI in multiple sclerosis. Neurology 50 (1998) 1282-1288
    • (1998) Neurology , vol.50 , pp. 1282-1288
    • van Walderveen, M.1    Kamphorst, W.2    Scheltens, P.3
  • 9
    • 0033586376 scopus 로고    scopus 로고
    • Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and changes in disability or impairment in multiple sclerosis: a meta-analysis
    • for the Gadolinium MRI Meta-analysis Group
    • Kappos L., Moeri D., Radue E., et al., for the Gadolinium MRI Meta-analysis Group. Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and changes in disability or impairment in multiple sclerosis: a meta-analysis. Lancet 353 (1999) 964-969
    • (1999) Lancet , vol.353 , pp. 964-969
    • Kappos, L.1    Moeri, D.2    Radue, E.3
  • 10
    • 33646710676 scopus 로고    scopus 로고
    • MRI T2 lesion burden in multiple sclerosis: a plateauing relationship with clinical disability
    • Li D., Held U., Petkau J., et al. MRI T2 lesion burden in multiple sclerosis: a plateauing relationship with clinical disability. Neurology 66 (2006) 1384-1389
    • (2006) Neurology , vol.66 , pp. 1384-1389
    • Li, D.1    Held, U.2    Petkau, J.3
  • 11
    • 39749200152 scopus 로고    scopus 로고
    • Disability and T2 MRI lesions: a 20-year follow-up of patients with relapse onset of multiple sclerosis
    • Fisniku L., Brex P., Altmann D., et al. Disability and T2 MRI lesions: a 20-year follow-up of patients with relapse onset of multiple sclerosis. Brain 131 (2008) 808-817
    • (2008) Brain , vol.131 , pp. 808-817
    • Fisniku, L.1    Brex, P.2    Altmann, D.3
  • 12
    • 0029730733 scopus 로고    scopus 로고
    • Accumulation of hypointense lesions ("black holes") on T1 spin-echo MRI correlates with disease progression in multiple sclerosis
    • Truyen L., van Waesberghe J., van Walderveen M., et al. Accumulation of hypointense lesions ("black holes") on T1 spin-echo MRI correlates with disease progression in multiple sclerosis. Neurology 47 (1996) 1469-1476
    • (1996) Neurology , vol.47 , pp. 1469-1476
    • Truyen, L.1    van Waesberghe, J.2    van Walderveen, M.3
  • 13
    • 0035091667 scopus 로고    scopus 로고
    • European/Canadian multicenter, double-blind, randomized, placebo-controlled study of the effects of glatiramer acetate on magnetic resonance imaging-measured disease activity and burden in patients with relapsing multiple sclerosis
    • for the Group ECGAS
    • Comi G., Filippi M., Wolinsky J., and for the Group ECGAS. European/Canadian multicenter, double-blind, randomized, placebo-controlled study of the effects of glatiramer acetate on magnetic resonance imaging-measured disease activity and burden in patients with relapsing multiple sclerosis. Ann Neurol 49 (2001) 290-297
    • (2001) Ann Neurol , vol.49 , pp. 290-297
    • Comi, G.1    Filippi, M.2    Wolinsky, J.3
  • 14
    • 0032864616 scopus 로고    scopus 로고
    • Magnetic resonance imaging results of the PRISMS trial: a randomized, double-blind, placebo-controlled study of interferon-beta 1a in relapsing-remitting multiple sclerosis: prevention of relapses and disability by interferon-beta 1a subcutaneously in multiple sclerosis
    • Li D., and Paty D. Magnetic resonance imaging results of the PRISMS trial: a randomized, double-blind, placebo-controlled study of interferon-beta 1a in relapsing-remitting multiple sclerosis: prevention of relapses and disability by interferon-beta 1a subcutaneously in multiple sclerosis. Ann Neurol 46 (1999) 197-206
    • (1999) Ann Neurol , vol.46 , pp. 197-206
    • Li, D.1    Paty, D.2
  • 15
    • 34247513840 scopus 로고    scopus 로고
    • MRI outcomes in a placebo-controlled trial of natalizumab in relapsing MS
    • Miller D., Soon D., Fernando K., et al. MRI outcomes in a placebo-controlled trial of natalizumab in relapsing MS. Neurology 68 (2007) 1390-1401
    • (2007) Neurology , vol.68 , pp. 1390-1401
    • Miller, D.1    Soon, D.2    Fernando, K.3
  • 16
    • 0034624942 scopus 로고    scopus 로고
    • Linomide in relapsing and secondary progressive MS: part I: trial design and clinical results
    • for the North American Linomide Investigators
    • Noseworthy J., Wolinsky J., Lublin F., et al., for the North American Linomide Investigators. Linomide in relapsing and secondary progressive MS: part I: trial design and clinical results. Neurology 54 (2000) 1726-1733
    • (2000) Neurology , vol.54 , pp. 1726-1733
    • Noseworthy, J.1    Wolinsky, J.2    Lublin, F.3
  • 17
    • 22844438117 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy and natalizumab-unforeseen consequences
    • Berger J., and Koralnik I. Progressive multifocal leukoencephalopathy and natalizumab-unforeseen consequences. N Engl J Med 353 (2005) 414-416
    • (2005) N Engl J Med , vol.353 , pp. 414-416
    • Berger, J.1    Koralnik, I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.