Ovarian Sertoli-Leydig cell tumor with heterologous gastrointestinal epithelium as a source of alpha-fetoprotein: A case report

Journal of Obstetrics and Gynaecology Research

Volumn 34, Issue 3, 2008, Pages 418-421

  Watanabe, Takafumi ^a   Yamada, Hidekazu ^a   Morimura, Yutaka ^b   Abe, Masafumi ^a   Motoyama, Teiichi ^c   Sato, Akira ^a  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^b Tsuboi Hospital   (Japan)

^c YAMAGATA UNIVERSITY   (Japan)

Author keywords

Alpha fetoprotein; Heterologous gastrointestinal epithelium; Ovary; Sertoli Leydig cell tumor

Indexed keywords

ALPHA FETOPROTEIN;

ADULT; ANDROBLASTOMA; ARTICLE; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; INTESTINE EPITHELIUM; LAPAROTOMY; MENSTRUAL IRREGULARITY; OMENTUM; PROTEIN BLOOD LEVEL; SALPINGOOOPHORECTOMY; TUMOR RECURRENCE;

ADULT; ALPHA-FETOPROTEINS; CHEMOTHERAPY, ADJUVANT; EPITHELIAL CELLS; FALLOPIAN TUBES; FEMALE; GASTROINTESTINAL TRACT; HUMANS; OMENTUM; OVARIAN NEOPLASMS; OVARIECTOMY; PERITONEAL NEOPLASMS; REMISSION INDUCTION; SERTOLI-LEYDIG CELL TUMOR;

EID: 45149103487     PISSN: 13418076     EISSN: 14470756     Source Type: Journal    
DOI: 10.1111/j.1447-0756.2008.00730.x     Document Type: Article

References (17)

1. Young RH, Scully RE. Ovarian Sertoli-Leydig cell tumors: a clinicopathological analysis of 207 cases. Am J Surg Pathol 1985 9 : 543 569.
2. Mooney E, Nogales FF, Tavassoli FA. Hepatocytic differentiation in retiform Sertoli-Leydig cell tumors: distinguishing a heterologous element from Leydig cells. Hum Pathol 1999 30 : 611 617.
3. Young RH, Perez-Atayde AR, Scully RE. Ovarian Sertoli-Leydig cell tumor with retiform and heterologous components: Report of a case with hepatocytic differentiation and elevated serum alpha-fetoprotein. Am J Surg Pathol 1984 8 : 709 718.
4. Talerman A. Ovarian Sertoli-Leydig cell tumor (androblastoma) with retiform pattern: a clinicopathologic study. Cancer 1987 60 : 3056 3064.
5. Motoyama I, Watanabe H, Gotoh A, Takeuchi S, Tanabe N, Nashimoto I. Ovarian Sertoli-Leydig cell tumor with elevated serum alpha-fetoprotein. Cancer 1989 63 : 2047 2053.
6. Gagnon S, Tetu B, Silva EG et al. Frequency of alpha-fetoprotein production by Sertoli-Leydig cell tumors of the ovary: an immunohistochemical study of eight cases. Mod Pathol 1989 2 : 63 67.
7. Singh ZN, Singh MK, Chopra P. Sertoli Leydig cell tumor with malignant heterologous elements and raised alpha-fetoprotein: a case report. J Obstet Gynaecol Res 1996 22 : 595 598.
8. Young RH, Prat J, Scully RE. Ovarian Sertoli-Leydig cell tumors with heterologous elements. I. Gastrointestinal epithelium and carcinoid: a clinicopathologic analysis of thirty-six cases. Cancer 1982 50 : 2448 2456.
9. Allen A, Hutton DA, Person JP. The MUC2 gene product: a human intestinal mucin. Int J Biochem Cell Biol 1998 30 : 797 801.
10. Ho SB, Roberton AM, Shekels LL et al. Expression cloning of gastric mucin complementary DNA and localization if mucin gene expression. Gastroenterology 1995 109 : 735 747.
11. Bartman AE, Buisine MP, Aubert JP et al. The MUC6 secretory mucin gene is expressed in a wide variety of epithelial tissues. J Pathol 1998 186 : 398 405.
12. Yasunami R, Hashimoto Z, Ogura T, Hirao F, Yamamura Y. Primary lung cancer producing alpha-fetoprotein: a case report. Cancer 1981 47 : 926 929.
13. Wahren B, Harmenberg J, Edsmyr F, Jakobsson P, Ingimarsson S. Possible tumour markers in patients with oesophagus cancer. Scand J Gastroenterol 1979 14 : 361 365.
14. Kodama T, Kameya T, Hirota T et al. Production of alpha-fetoprotein, normal serum proteins, and human chorionic gonadotropin in stomach cancer: histologic and immunohistochemical analyses of 35 cases. Cancer 1981 48 : 1647 1655.
15. Klavins JV. Tumor markers of pancreatic carcinoma. Cancer 1981 47 : 1597 1601.
16. Belanger L, Baril P, Guertin M et al. Oncodevelopmental and hormonal regulation of alpha 1-fetoprotein gene expression. Adv Enzyme Regul 1983 21 : 73 99.
17. Cohen MB, Mulchahey KM, Molnar JJ. Ovarian endodermal sinus tumor with intestinal differentiation. Cancer 1986 57 : 1580 1583.