Microsomal epoxide hydrolase (EPHX1), slow (exon 3, 113His) and fast (exon 4, 139Arg) alleles confer susceptibility to squamous cell esophageal cancer

Toxicology and Applied Pharmacology

Volumn 230, Issue 2, 2008, Pages 247-251

  Jain, Meenu ^a   Tilak, Anup Raj ^b   Upadhyay, Rohit ^a   Kumar, Ashwani ^b   Mittal, Balraj ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

^b CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

EPHX1; Esophageal cancer; Polymorphism

Indexed keywords

ALCOHOL; ARGININE; HISTIDINE; TYROSINE;

ADULT; AGED; ALCOHOL CONSUMPTION; ALLELE; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CASE CONTROL STUDY; CHEMICAL STRUCTURE; CIGARETTE SMOKING; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; EPHX1 GENE; ESOPHAGUS CANCER; EXON; FEMALE; GENE INTERACTION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; INDIAN; MAJOR CLINICAL STUDY; MALE; MUTATOR GENE; OCCUPATIONAL EXPOSURE; PATHOGENESIS; PHENOTYPE; POLYMERASE CHAIN REACTION; PROGNOSIS; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SQUAMOUS CELL CARCINOMA; TUMOR LOCALIZATION;

ADULT; AGED; ALCOHOL DRINKING; ALLELES; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; ENVIRONMENTAL EXPOSURE; EPOXIDE HYDROLASES; ESOPHAGEAL NEOPLASMS; EXONS; FEMALE; GENOTYPE; HUMANS; INDIA; MALE; MICROSOMES; MIDDLE AGED; OCCUPATIONAL EXPOSURE; PHENOTYPE; POLYMORPHISM, GENETIC; RISK; SMOKING;

NICOTIANA TABACUM;

EID: 45049086522     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.02.023     Document Type: Article

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